Material Safety Data Sheet: N-Octyl Bromide

1. Identification

Product Name: N-Octyl Bromide
Synonyms: 1-Bromooctane, Octyl bromide
Chemical Formula: C8H17Br
CAS Number: 111-83-1
Recommended Use: Laboratory chemicals, chemical synthesis
Supplier Details: Contact information for manufacturer or distributor, emergency contact phone number, address for correspondence and further information

2. Hazard Identification

GHS Classification: Skin irritation (Category 2), Eye irritation (Category 2A), Specific target organ toxicity-single exposure (Category 3)
Label Elements: Exclamation mark symbol, signal word "Warning"
Hazard Statements: Causes skin irritation, causes serious eye irritation, may cause respiratory irritation
Precautionary Statements: Avoid breathing vapors, wash hands thoroughly after handling, use only outdoors or in a well-ventilated area, wear protective gloves and eye protection, if on skin wash with plenty of water, if in eyes rinse cautiously with water for several minutes
Potential Health Effects: Inhalation may cause throat irritation, coughing, or shortness of breath, contact with skin may result in redness and discomfort, eye contact can lead to pain and blurred vision, ingestion may cause nausea or irritation to digestive tract

3. Composition / Information on Ingredients

Chemical Name: N-Octyl Bromide
Concentration: 98-100%
Impurities: Small amounts of homologues or isomers possible from manufacture
Molecular Weight: 193.13 g/mol
Hazardous Components: No significant additives or stabilizers reported

4. First Aid Measures

Inhalation: Move individual to fresh air, keep victim at rest, seek medical advice if symptoms persist
Skin Contact: Remove contaminated clothing immediately, flush exposed skin with plenty of water for at least 15 minutes, seek attention if irritation remains
Eye Contact: Rinse carefully with water for at least 15 minutes, holding eyelids open, remove contact lenses if present, obtain medical help if discomfort or vision changes continue
Ingestion: Rinse mouth with water, do not induce vomiting, offer water to drink, get prompt medical attention, never administer anything by mouth to an unconscious person
General Notes: Provide physician with details of the substance, monitor vital signs during acute exposure

5. Fire-Fighting Measures

Suitable Extinguishing Media: Use dry chemical, foam, or carbon dioxide, water spray can cool exposed containers but may spread liquid
Special Hazards: Combustion may release toxic gases such as hydrogen bromide, carbon oxides, flammable vapors can form mixtures with air
Protective Equipment: Firefighters need self-contained breathing apparatus and full protective gear, prevent runoff from entering drains
Advice for Firefighters: Approach from upwind, remove containers from danger area if safe, use water fog to reduce vapors

6. Accidental Release Measures

Personal Precautions: Wear splash goggles, chemical resistant gloves, suitable protective clothing, avoid breathing vapors or contact with material
Environmental Precautions: Prevent spills from entering waterways or soil, contain leak with sand or inert absorbent, block discharge to drains
Cleanup Methods: Absorb with non-combustible material, collect and place in suitable containers for disposal, ventilate area thoroughly

7. Handling and Storage

Handling: Handle in a well-ventilated area away from ignition sources, avoid skin or eye contact, do not breathe in vapors, wash hands after handling, only use with appropriate PPE
Storage: Store in cool, dry, well-ventilated space in tightly closed original container, keep away from incompatible substances like strong oxidizers, acids and bases, avoid direct sunlight, store away from food and drink

8. Exposure Controls and Personal Protection

Occupational Exposure Limits: No established ACGIH or OSHA limits for N-Octyl Bromide, minimize exposure using available engineering controls, monitor air concentrations in work area
Engineering Controls: Use fume hood, ensure local exhaust and adequate ventilation
Personal Protective Equipment: Safety goggles, laboratory coat or chemical apron, nitrile or neoprene gloves, appropriate respirator if vapor concentrations become high
General Hygiene: Do not smoke, eat, or drink in area where material is handled, launder contaminated clothing before reuse, wash skin thoroughly after contact

9. Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Mild characteristic odor
Melting Point: -66°C
Boiling Point: 201-202°C
Flash Point: >100°C (closed cup)
Flammability: Not easily ignited, but combustible with strong flame
Vapor Pressure: Low at room temperature
Solubility: Insoluble in water, miscible with organic solvents like ether or ethanol
Density: 1.118 g/cm³ at 25°C
Viscosity: Not highly viscous
Auto-ignition Temperature: >200°C
Molecular Structure: Linear eight-carbon chain with terminal bromine atom

10. Stability and Reactivity

Chemical Stability: Stable at ordinary ambient conditions, slowly decomposes at elevated temperatures
Incompatible Materials: Strong oxidizing agents (risk of violent reaction), strong alkalis, strong acids
Decomposition Products: Hydrogen bromide, carbon monoxide, carbon dioxide in fire
Hazardous Polymerization: Not expected under normal storage and use conditions

11. Toxicological Information

Acute Toxicity: LD50 (oral, rat): estimated above 2000 mg/kg, inhalation hazard low due to low volatility
Skin Corrosion/Irritation: Moderate skin irritant in animals, reddening and discomfort observed in exposed area
Serious Eye Damage/Irritation: Can cause redness, pain, watery eyes
Respiratory Sensitization: May trigger irritation, no clear evidence of sensitization
Carcinogenicity: Not classified by IARC, NTP, or OSHA
Other Effects: May cause headache, nausea, dizziness if inhaled at high concentrations, no chronic effects documented in standard toxicological studies

12. Ecological Information

Ecotoxicity: Harmful to aquatic organisms, may cause long-lasting effects in the environment
Persistence and Degradability: Not readily biodegradable, tends to persist in soil and sediments
Bioaccumulative Potential: Moderate potential for bioaccumulation due to fat-solubility
Mobility in Soil: Low mobility, adheres to organic matter
Other Adverse Effects: Release in large quantities could harm aquatic and terrestrial ecosystems, avoid discharge to waterways under all circumstances

13. Disposal Considerations

Disposal Methods: Dispose in accordance with local, state, and federal regulations, incinerate at a licensed facility suitable for halogenated organic chemicals
Container Disposal: Triple rinse empty container, send to certified drum reconditioner or take to approved waste facility
Precautions: Do not pour into sewer, surface water, or soil, ensure waste handler is informed about the hazards present

14. Transport Information

UN Number: UN 1993
Proper Shipping Name: Flammable Liquid, n.o.s. (contains N-Octyl Bromide)
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: III
Marine Pollutant: Yes
Special Precautions: Ensure containers remain tightly sealed, transport upright, avoid extreme temperatures during shipment, comply with all relevant regulations for hazardous chemicals

15. Regulatory Information

TSCA: Listed on United States Toxic Substances Control Act Inventory
REACH (EU): Registered or pre-registered, subject to restrictions for specific uses
SARA Title III: Not identified as an extremely hazardous substance
OSHA Hazard Communication: Meets criteria for hazardous substances
Other Regulations: Subject to workplace right-to-know requirements, follows international transport and labeling rules for dangerous goods