Bromohexane MSDS (Material Safety Data Sheet)

Identification

Product Name: Bromohexane
Chemical Name: 1-Bromohexane
Synonyms: n-Hexyl bromide
CAS Number: 111-25-1
Molecular Formula: C6H13Br
Recommended Use: Laboratory reagent, chemical synthesis intermediate
Supplier Information: Refer to actual supplier’s contact details on packaging
Emergency Contact: Poison Control Center or designated campus chemical spill response

Hazard Identification

Classification: Flammable liquid, acute toxicity (inhalation, oral, dermal), skin and eye irritant, suspected reproductive hazard
Label Elements: Skull and crossbones (toxic), flame (flammable), exclamation mark (irritant)
Signal Word: Danger
Hazard Statements: Causes skin irritation, causes serious eye irritation, harmful if swallowed or inhaled, may be fatal in large quantities, causes respiratory tract irritation, suspected of damaging fertility or the unborn child
Precautionary Statements: Keep away from heat or open flames, avoid breathing vapors, wash hands thoroughly after handling, use protective gear, seek immediate medical attention if exposure occurs

Composition / Information on Ingredients

Chemical Name: 1-Bromohexane
Common Name/Synonyms: n-Hexyl bromide
Chemical Formula: C6H13Br
Concentration: 98-100%
Impurities: Trace related alkyl bromides at <1% levels
CAS Number: 111-25-1

First Aid Measures

Eye Contact: Flush with plenty of running water for at least 15 minutes, keep eyelids apart, remove contact lenses if present, get medical attention without delay
Skin Contact: Remove contaminated clothing, rinse skin with copious water and soap, seek medical care for irritation or burns
Inhalation: Move victim to fresh air, keep at rest and warm, get medical help if symptoms (dizziness, coughing, shortness of breath) persist
Ingestion: Rinse mouth thoroughly, never induce vomiting, do not give anything by mouth unless directed by a healthcare provider, call Poison Control or medical provider immediately
Most Important Symptoms: Burning sensations, redness, pain, coughing, headache, nausea, difficulty breathing in severe cases

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, foam, CO2, water spray for cooling exposed containers—avoid using direct water jets
Hazards from Combustion: Produces bromine-containing fumes, hydrogen bromide, carbon monoxide, carbon dioxide
Protective Equipment: Wear full turnout gear and self-contained breathing apparatus
Precautions: Remove containers from fire area if safe, fight fire from sheltered location or maximum distance possible, keep away from drains or waterways to limit runoff contamination

Accidental Release Measures

Emergency Procedures: Evacuate non-essential personnel, ventilate area, shut off sources of ignition
Personal Protection: Wear chemical splash goggles, respirator (organic vapor type), chemical-resistant gloves, lab coat or overall
Containment Methods: Confine spill using inert absorbent (sand, vermiculite), avoid liquid entry into drains or water sources
Cleanup Procedure: Scoop up absorbent material, transfer waste to sealable chemical waste containers, clean thoroughly with detergent and water, ventilate area before re-entering
Environmental Caution: Prevent escape to soil, sewers, watercourses—notify authorities if contamination occurs

Handling and Storage

Safe Handling Advice: Avoid contact with skin, eyes, and clothing, avoid breathing vapors or mists, open and use containers within fume hoods or well-ventilated laboratories, ground and bond transfer containers to prevent static discharge
Storage Conditions: Keep tightly closed in original, labeled container, store away from incompatible materials (strong oxidizers, acids, bases), protect from physical damage, keep in a dry, cool, well-ventilated space, minimize direct sunlight exposure
Specific advice: Restrict access to trained personnel, store under lock in dedicated chemical flammable store

Exposure Controls and Personal Protection

Exposure Limits: No ACGIH or OSHA standards—exposure should be minimized as for other alkyl halides
Engineering Controls: Use with local exhaust ventilation, keep fume hood operational, monitor air quality in storage and workplace
Personal Protective Equipment: Safety goggles, chemical splash-resistant gloves (nitrile, neoprene), flame-retardant lab coat, organic vapor respirator if ventilation inadequate
Hygiene Measures: Wash hands, face, forearms immediately after handling, launder clothing before reuse, do not eat, drink, or smoke while using product

Physical and Chemical Properties

Appearance: Colorless to pale straw yellow liquid
Odor: Mild, sweet characteristic odor similar to other alkyl halides
Melting Point: -62°C
Boiling Point: ~155°C
Flash Point: 51°C (closed-cup)
Vapor Density (air = 1): >1 (heavier than air)
Specific Gravity: 1.165
Solubility in Water: Practically insoluble
Vapor Pressure: 2 mm Hg at 25°C
Partition Coefficient (n-octanol/water): log Pow ~3.8
Viscosity: Low viscosity, flows easily at room temperature
Auto-Ignition Temperature: 210°C
Decomposition Temperature: Not well defined; harmful gases released above 200°C

Stability and Reactivity

Chemical Stability: Stable under standard laboratory and storage conditions
Reactivity: Not self-reactive, may undergo dehydrohalogenation in basic environments
Incompatible Materials: Strong oxidizers, acids, bases, alkali metals, powdered metals
Hazardous Decomposition: Hydrogen bromide, bromine, carbon monoxide, carbon dioxide generated on strong heating or burning
Hazardous Polymerization: Not known to occur under normal use
Conditions to Avoid: Heat, sparks, open flames, static electricity, direct sunlight, contact with incompatible materials

Toxicological Information

Routes of Exposure: Eyes, skin, inhalation, ingestion
Acute Toxicity: LD50 oral (rat): 2900 mg/kg; LD50 dermal (rabbit): ~2,500 mg/kg
Effects from Exposure: Causes skin and eye irritancy, may cause respiratory tract burns, headache, dizziness, nausea, central nervous system depression possible
Chronic Exposure: Prolonged exposure may sensitize skin or respiratory tract, potential liver or kidney damage, suspected reproductive hazard based on related compounds
Carcinogenicity: Not classified by IARC, ACGIH, NTP or OSHA—no definitive human data, treat as a chemical of unknown chronic effects
Mutagenicity and Reproductive Toxicity: No large-scale studies in humans, handled as potentially hazardous

Ecological Information

Aquatic Toxicity: Toxic to aquatic organisms, possible bioaccumulation in aquatic environments
Persistence: Degrades slowly in soil and water, persistence expected because of low water solubility, significant vapor-phase movement may occur
Mobility: Sinks in water, likely to adsorb to sediment or organic matter
Bioaccumulation Potential: High; log Pow above 3 indicates potential to accumulate in aquatic food chains
Other Environmental Hazards: May contribute to ozone layer depletion if released to atmosphere, not biodegradable, long-term hazards to wildlife and waterfowl

Disposal Considerations

Waste Disposal Methods: Collect and store waste in sealed, labeled chemical containers, provide disposal via licensed hazardous waste contractor
Precautions: Do not dispose via municipal sewers or landfill, avoid spills to soil or waterways, rinse empty containers three times with compatible solvent before discarding
Special Handling Notes: Incineration in chemical incinerator with afterburner and scrubber strongly recommended, follow local, regional, federal disposal regulations

Transport Information

UN Number: UN 2286
Proper Shipping Name: 1-Bromohexane
Transport (Hazard Class): 3 (Flammable liquid)
Packing Group: III
Label: Flammable liquid
Marine Pollutant: Yes
Special Transport Precautions: Secure all containers upright and prevent movement, keep away from sources of ignition, ship according to IATA, IMDG, and DOT requirements for chemical freight

Regulatory Information

OSHA: Covered under Hazard Communication Standard
TSCA: Listed on Toxic Substances Control Act inventory
SARA Title III: Section 311/312 (Acute Health Hazard, Fire Hazard); not listed under Section 313 or CERCLA
RCRA: Waste code U000 for halogenated organic materials
California Proposition 65: Not specified as a listed chemical, but caution warranted due to similarity with other alkyl bromides
EU Regulations: Classed as hazardous under CLP Regulation (EC) No 1272/2008
WHMIS (Canada): B2, D1B, D2B (Flammable, Toxic, Irritant)
Other National/Regional: Employers must provide training and access to full MSDS content; use as industrial chemical subject to region-specific restrictions