Material Safety Data Sheet: Bromoacetyl Bromide

Identification

Product Name: Bromoacetyl Bromide
Chemical Formula: C2H2Br2O
Synonyms: α-Bromoacetyl bromide, Acetyl bromide, bromo-
CAS Number: 598-21-0
Recommended Use: Laboratory chemical, chemical synthesis
Manufacturer/Supplier Information: Contact details available on company label or invoice

Hazard Identification

GHS Classification: Acute Toxicity (Oral, Dermal, Inhalation) Category 2; Skin Corrosion Category 1A; Serious Eye Damage Category 1
Hazard Statements: Toxic if swallowed, in contact with skin or if inhaled. Causes severe skin burns and eye damage.
Pictograms: Skull and crossbones, corrosive symbol
Precautionary Statements: Avoid all contact, wear personal protective equipment, handle only in well-ventilated environments
Routes of Exposure: Inhalation, skin and eye contact, ingestion

Composition / Information on Ingredients

Chemical Name: Bromoacetyl Bromide
Concentration: 99% or higher
Impurities: None of significance detected during batch testing in certified labs
Molecular Weight: 219.84 g/mol

First Aid Measures

Inhalation: Get person to fresh air immediately. If breathing difficulties or unease develop, seek emergency medical attention. Oxygen or artificial respiration, as medical staff deems necessary.
Skin Contact: Remove exposed clothing and rinse skin thoroughly with running water for at least 15 minutes. Seek medical attention for burns or irritation.
Eye Contact: Rinse eyes gently with large amounts of water for at least 15 minutes, lifting upper and lower eyelids. Urgent medical treatment required.
Ingestion: Rinse mouth with water only if victim is conscious. Do not induce vomiting. Immediate medical support is critical.
Most Important Symptoms: Burning, pain, blistering, breathing problems, nausea

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam. Do not use water streams directly on substance.
Special Hazards: Releases corrosive, toxic gases (hydrogen bromide, carbon monoxide) when burning.
Protective Equipment for Firefighters: Full-body chemical protection suit and self-contained breathing apparatus.
Firefighting Advice: Avoid inhaling gases, keep containers cool by spraying with water from a safe distance.

Accidental Release Measures

Personal Precautions: Evacuate area if spill occurs indoors. Ventilate well. Wear full protective clothing, chemical goggles, respirator, and gloves.
Environmental Precautions: Avoid runoff into storm drains, soil, or surface waters. Notify response team for cleanup.
Cleanup Methods: Absorb spill with inert dry material (vermiculite, sand), scoop up and place in container for disposal. Clean affected area thoroughly.

Handling and Storage

Handling: Use in a fume hood with adequate ventilation. Do not breathe fumes. Avoid skin/eye contact. Use appropriate PPE: impervious gloves, safety goggles, lab coat.
Storage: Store locked-up, in tightly closed containers, away from moisture and incompatible substances (such as water, alcohols, bases, strong oxidizing agents). Keep in a cool, well-ventilated, flame-proof area.
Hygiene: Wash thoroughly after handling. Remove contaminated clothing and clean before reuse.

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established limits for this specific chemical. Keep exposures minimized and monitored.
Engineering Controls: Use fume hood or equivalent exhaust ventilation.
Personal Protective Equipment: Chemical-resistant gloves (nitrile or better), goggles or face shield, long-sleeved lab coat, closed-toe shoes, respiratory protection where ventilation is inadequate.

Physical and Chemical Properties

Appearance: Clear to pale yellow liquid
Odor: Sharp, irritating, pungent
Boiling Point: 119-121°C
Melting Point: -56°C
Flash Point: Not available
Solubility in Water: Reacts violently
Vapor Pressure: 2.7 mmHg at 20°C
Density: 2.241 g/cm³ at 25°C

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Reacts with water, alcohols, strong bases, and strong oxidizing agents, releasing heat and toxic vapors
Hazardous Decomposition Products: Hydrogen bromide, carbon monoxide, carbon dioxide
Polymerization: Not known to polymerize

Toxicological Information

Acute Toxicity: LD50 (oral, rat): 70 mg/kg; highly toxic by inhalation, skin absorption
Corrosive Effects: Causes severe burns on all tissue contacted
Sensitization: No reliable data on repeated exposure; should be treated as a strong irritant and potential sensitizer
Symptoms of Overexposure: Burning sensation, breathing difficulty, chest pain, severe tissue damage, nausea, vomiting, visual impairment
Chronic Effects: No long-term data, but repeated exposure likely to result in permanent tissue damage

Ecological Information

Aquatic Toxicity: Harmful to aquatic life with long-lasting effects
Environmental Behavior: Hydrolyzes rapidly, products may be harmful to aquatic organisms
Persistence and Degradability: Not persistent; rapid breakdown in water results in toxic by-products
Bioaccumulation Potential: Not expected to bioaccumulate due to rapid hydrolysis
Mobility in Soil: Highly mobile and reactive, local contamination possible

Disposal Considerations

Waste Treatment Methods: Collect waste in clearly labeled hazardous chemical containers. Do not dispose of in drains or with regular trash.
Disposal Instructions: Send to licensed hazardous waste disposal facility. Neutralize carefully before disposal under expert supervision.
Contaminated Packaging: Treat as hazardous material and arrange disposal through approved hazardous waste handler.

Transport Information

UN Number: 2224
UN Proper Shipping Name: Bromoacetyl Bromide
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: I (highest danger)
Environmental Hazards: Marine pollutant
Transport Precautions: Use strong, sealed containers. Prevent leakage during transport. Follow emergency response guidelines for spills in transit

Regulatory Information

Safety, Health and Environmental Regulations: Subject to strict chemical safety rules in most countries (OSHA, EPA, REACH, WHMIS, etc.)
Labeling Requirements: Proper hazard statements, precautionary phrases, and pictograms required.
Restricted Uses: Not for food, drug, or household use
Reporting Requirements: Immediate reporting of significant spills or exposures to authorities as set by local law