4-Bromotoluene: A Detailed Commentary
Historical Development
Chemists have relied on derivatives of toluene since the 19th century, and 4-bromotoluene emerged as a valued compound once halogenation of aromatic hydrocarbons gained traction. Before modern industrial synthesis, researchers found functionalized toluenes enticed possibilities both in exploration and production of colorants and pharmaceuticals. In academic labs, the drive to improve selectivity in bromination led to this regioisomer as a favored intermediate. As demand for more versatile intermediates increased, the large-scale synthesis of 4-bromotoluene started shaping segments of specialty chemicals production. Not every early experiment produced pure para isomer, so advances like selective catalytic methods and controlled temperature processes made a difference for consistent quality in today’s chemical manufacturing.
Product Overview
4-Bromotoluene, an aromatic compound, includes a toluene core with a bromine atom at the para position. This simple change opens up a roster of uses in pharmaceutical synthesis, agrochemical intermediates, and specialty material production. Manufacturers package it mainly as a clear to pale yellow liquid, ensuring purity benchmarks necessary for further modifications and coupling reactions. Chemical suppliers often pitch 4-bromotoluene for its role in Suzuki couplings and Grignard syntheses, both crucial steps in building up more complex structures. Reliable sources make all the difference here, as even minor impurities lead to snagged downstream processes or unwanted byproducts in sensitive transformations. The compound's directness—toluene backbone and an easy halogen handle—sets it up for broad adoption across diverse research and industrial applications.
Physical & Chemical Properties
This compound has a molecular formula of C7H7Br. With a melting point sitting around −39°C and boiling in the neighborhood of 184°C, 4-bromotoluene stays a liquid at typical room temperatures. Chemists appreciate its density, roughly 1.39 g/cm3, which helps when separating layers in practical benchwork. It gives off a faint aromatic odor, a reminder of its toluene heritage. As for solubility, it barely mixes with water but dissolves well in most organic solvents, including ether, acetone, and alcohols. Its refractive index clocks in near 1.54. Flash point measures roughly 67°C, so anyone handling this substance needs to deal with it like most volatile aromatics—use ventilation, avoid ignition sources, and wear protective gear.
Technical Specifications & Labeling
Producers focus on guaranteeing assay values higher than 98% for synthetic applications. Labels commonly cite CAS number 106-38-7. The UN Transport Code classifies it as a flammable liquid, prompting storage in properly ventilated, temperature-controlled environments. Typical barrels or bottles host batch-specific data, including purity by gas chromatography, water content by Karl Fischer titration, and residual halogen contaminants. Responsible vendors include signal words and hazard pictograms from GHS guidelines. For research or regulated manufacturing, trace impurity levels—iron, heavy metals, or other halides—often dictate whether a batch lives up to the selectivity required for downstream synthesis. Documentation includes safety data sheets, certificates of analysis, and transport instructions to avoid any regulatory snags.
Preparation Method
Laboratories usually get 4-bromotoluene by selective bromination of toluene. Success depends on directing the reaction to form the para isomer, since toluene naturally gives three possible products: ortho, meta, and para. Modern syntheses tend to leverage light or Lewis acids to control the addition. For instance, mixing toluene with bromine under controlled, cool conditions, along with ferric bromide or aluminum chloride as a catalyst, raises the fraction of para compound. Older methods—straightforward but wasteful—often led to a mixture that needed extensive fractionation by distillation. Continuous flow techniques and green chemistry tweaks, such as using environmentally safer bromine sources, are starting to catch more attention. Keeping byproduct levels in check stays critical, given safety and waste disposal standards. All properly run syntheses finish with purification, like fractional distillation or recrystallization, to deliver a product up to spec for every subsequent reaction.
Chemical Reactions & Modifications
What makes 4-bromotoluene so useful—building block potential for cross-coupling chemistry. In Suzuki-Miyaura reactions, this compound joins with boronic acids in the hands of a skilled chemist wielding palladium catalysts to generate biaryl structures. In Grignard formation, magnesium reacts with the bromo group to yield a reactive organomagnesium intermediate, which then attacks a wide range of carbonyl compounds. Nucleophilic aromatic substitution becomes viable with stronger electron-withdrawing groups; still, for most transformations, the methyl and bromo combination unlocks options not available to simple toluene itself. Oxidizing the methyl group gives 4-bromobenzaldehyde or 4-bromobenzoic acid, depending on strength and conditions. Reductive debromination or metal-catalyzed transfers keep this compound present in any full-spectrum synthesis toolkit.
Synonyms & Product Names
Chemists know this molecule as para-bromotoluene or p-bromotoluene. Some catalogues list it as 1-bromo-4-methylbenzene or 4-methylbromobenzene. Several languages have their own translations, yet the "4-" prefix clearly points to the bromine position on the ring. Standard chemical supply houses keep all these names listed for clarity, but regulatory filings—the sorts submitted for REACH or TSCA—rely on the precise nomenclature laid out by IUPAC. In many commercial databases, entries match synonyms to the unique CAS identifier, which helps procurement teams steer clear of mistakes during ordering or inventory work.
Safety & Operational Standards
Just because 4-bromotoluene doesn’t carry notorious toxicity doesn’t mean chemists treat it with indifference. Its vapors, like those from other aromatic bromides, can irritate the eyes, skin, and upper respiratory tract. Solid operational standards require containment—fume hoods, gloves, goggles, and flame-proof lab coats, especially given its flammability. Storage demands closed, labeled containers in cool, fire-resistant spaces. Inhalation or skin exposure gets prompt first aid attention. Spill procedures call for absorbent materials and careful waste segregating, avoiding the pour-down-the-drain mistakes of the past. Facilities holding significant quantities must keep fire extinguishers handy and regularly train staff on emergency handling. Documented risk assessments back up every batch in academic or industrial labs, with attention to local rules and global labeling.
Application Area
4-Bromotoluene features strongly in pharmaceutical research, as its structure makes it tailor-made for Suzuki coupling or other arylation strategies in drug lead development. Some herbicides and pesticides come together through intermediates built from this compound, too. In electronics, synthesizing certain advanced polymers starts with aromatic halides like this. Dye and pigment industries see value in the para-bromo arrangement, since specific color profiles require fine-tuned functional groups. Research labs, both academic and private, view 4-bromotoluene as a reliable “handle” for extending aromatic systems without fuss, thanks to the predictable reactivity. Its chemical profile supports scale-up from grams to multi-ton production, letting it bridge the gap between discovery and manufacturing.
Research & Development
Chemists keep refining greener bromination routes and more selective catalysts for production. Some recent patents describe methods using ionic liquids or polymer-supported reagents to minimize hazardous waste. Teams in pharmaceutical R&D use 4-bromotoluene to build out libraries of potential drugs by stitching different groups onto the aromatic platform. Automation and machine learning now help pick reaction conditions for modifications, especially in high-throughput settings. Materials scientists probe new uses for this compound in the synthesis of organic semiconductors and specialty plastics. Biochemists look at biotransformations—engineered microbes or enzymes—to effect toluene functionalization steps, offering alternatives that might one day outcompete classic chemical routes.
Toxicity Research
There’s still a need for more long-term toxicity data on aromatic halides like 4-bromotoluene. Animal studies point to mild acute toxicity; high concentrations cause lethargy, respiratory issues, or organ irritation, but documentation stays sparse for chronic exposure. Dermatological reports advise against skin and eye contact, and safety data sheets recommend avoiding ingestion or inhalation. Environmental scientists know that brominated aromatics resist rapid microbial breakdown, raising concerns about persistence if spilled or released. Regulators look at analogues like bromobenzene for risk assessments, but every new study underscores the need to handle material safely and minimize unnecessary release. Non-target aquatic life could see effects, prompting waste managers to safeguard effluent disposal rigorously. In my experience, robust PPE and clear disposal protocols form the backbone of safe handling, far outpacing reliance on material safety data sheets alone.
Future Prospects
The search for even cleaner methods to make and use 4-bromotoluene benefits from pressure to reduce environmental impact. Biocatalysis and electrochemical bromination hold promise, especially if energy use and hazardous byproducts drop. In downstream chemistry, chemists look for coupling reactions demanding fewer precious metal catalysts or milder conditions. With growing demand for tailored pharmaceuticals and smart materials, 4-bromotoluene sits in a sweet spot as an adaptable building block. Industry partnerships between process developers and green chemistry startups could yield waste-reducing innovations. Real-time reaction monitoring—machine vision, in-line spectroscopy—will likely play a bigger role, cutting batch failures and boosting reproducibility. Students and professionals alike recognize the value in maintaining rigorous safety and environmental standards, ensuring that this classic aromatic keeps showing up in new applications without marking a bigger eco-footprint.
The Basics of 4-Bromotoluene
4-Bromotoluene comes up pretty often in the world of organic chemistry labs, both in school and inside research facilities. If you split the name apart, you get two clues about what makes up this molecule: “Bromo” points to a bromine atom, and “toluene” means a methylbenzene foundation. Put together, 4-Bromotoluene carries the chemical formula C7H7Br.
Why Formulas Matter Beyond the Classroom
Walk into a chemistry stockroom and try grabbing reagents without knowing their formulas; confusion quickly follows, and mistakes can have real consequences. The formula C7H7Br tells you that this molecule is a benzene ring (six carbon atoms in a ring, with alternating double bonds), a methyl group attached to it (CH3), and a bromine atom taking up the “4” slot across the ring from the methyl group. Folks rely on these formulas to plan reactions, evaluate purity, or estimate yields for larger projects or manufacturing runs.
Experience Talks: Handling Chemicals Safely
Years in the lab have shown that mixing up molecules, even simple ones, leads to wasted batches, safety hazards, or skewed experimental data. 4-Bromotoluene looks similar to other toluene derivatives, but swapping a bromine at the wrong position changes how it reacts and how safe it is to handle. The C7H7Br formula ensures there’s no mistake — you’ve got a molecule with a molecular weight of about 171 g/mol, and you’re not dealing with its cousins like 2-bromotoluene or 3-bromotoluene, each reacting differently in substitution and coupling reactions. Mislabeling could shut down an entire production line or halt a semester’s research.
Broader Value: From Synthesis to Applications
People working in pharmaceutical labs lean heavily on 4-Bromotoluene’s properties. Adding a bromine doesn’t just alter the molecule’s identity, it enables very specific reactions to build new medicines or materials. The para- (4-) position supports precision in Suzuki-Miyaura or Heck couplings, both of which help assemble larger, more complex molecules safely and efficiently. If a process uses the wrong isomer, reaction outcomes change, and costly ingredients might go to waste.
Quality Checks and Sourcing
In commercial realms, the C7H7Br formula helps with inventory tracking, regulatory checks, and ensuring the authenticity of the product. Many organizations classify and transport chemicals based on their unique formulas to stay in line with safety codes and environmental regulations. If you’ve ordered 4-Bromotoluene but get a bottle with an inconsistent formula or labeling, it’s worth flagging it for thorough QC testing. Counterfeiting and accidental swaps happen more than people think — formulas act as the industry’s primary defense.
Paving the Way Forward
Familiarity with formulas like C7H7Br turns guesswork into confidence when designing experiments or building new technology. There’s a story behind every chemical label in the lab, and it starts with something as seemingly basic as the right formula. Double-checking, verifying suppliers, training staff, and using well-maintained databases all help to avoid costly mix-ups. At the end of the day, the humble chemical formula stands as more than a string of letters and numbers — it’s a vital tool for anyone serious about science, innovation, or safety.
What 4-Bromotoluene Brings to the Table
4-Bromotoluene shows up as a chemical building block that a lot of people never hear about, but it plays a crucial role behind the scenes, especially in research labs and manufacturing lines. If you’ve spent any time working with organic synthesis—particularly pharmaceuticals or specialty compounds—you’ll probably recognize its sharp, sweet odor and almost transparent look.
Crafting New Molecules in the Lab
Pharmaceutical companies keep 4-Bromotoluene on hand for one reason: its bromine atom can get switched out for all sorts of other groups. This swap lies at the heart of what chemists call cross-coupling reactions. Chemists like using the Suzuki, Heck, or Sonogashira methods, which need that bromine piece because it breaks off easily. In my experience, the science might sound technical, but in practice, it means more efficient access to breakthrough medications—antivirals, pain relievers, cancer drugs, you name it. These days, a lot of the hope for better treatments starts at this exact stage.
Getting to Dyes and Pigments
Dyes and pigments often owe their color to compounds built from benzene rings like 4-Bromotoluene. Chemical manufacturers can add new pieces to the toluene ring, shifting colors or boosting their fastness against sunlight or water. People who work with specialty inks and plastics see better end products because of tweaks made using this simple compound. Every time I see the exact shade of blue in a well-printed label or a brightly colored toy, I think about the lab work that made it possible.
Making Pesticides and Agricultural Chemicals
Agriculture doesn’t always come to mind when chemistry is the topic, but crop protection relies heavily on careful molecular engineering. Scientists handle 4-Bromotoluene to stitch together more complicated molecules that ward off pests or diseases. Farmers can't afford to take chances with crop failure, so these tools often mean the difference between a good harvest and wasted effort. Tracing it back, so much of the lab work started with bromotoluenes just like this.
Synfuels and Plastics Industry
4-Bromotoluene serves as a stepping stone for polymers and specialty plastics. Certain types of engineering resins need aromatic units where a methyl group sits next to a functional handle like the bromine atom here. The electronics market, for instance, relies on plastics that don’t deform or lose their insulating features under heat. Materials science teams can swap, shape, and test materials at the molecular level because this starting molecule lets them make tailored monomers.
Challenges and Room for Improvement
Working with 4-Bromotoluene isn’t risk-free. Like many chemicals in the halogenated toluene family, it calls for solid ventilation and personal protective gear. From my own days at the lab bench, I learned the hard way to respect rules about fume hoods and proper labeling. Industry could improve on waste management by recycling leftover brominated byproducts, which would help cut down on the chemical load heading for waste treatment. Green chemistry pushes for new routes to make, use, and recover these molecules. As regulations grow tighter, companies and scientists now work closer to find safer ways of handling, synthesizing, and reusing 4-Bromotoluene.
Understanding the Risks
4-Bromotoluene doesn’t show up in headlines much, but anyone who has handled chemicals for research or manufacturing knows it deserves respect. It gives off a faint odor and looks like a clear liquid, which tricks some folks into thinking it’s no big deal. This compound can irritate the skin, eyes, and lungs, and packs more hazards when heated or stored carelessly. If vapors gather, they become both a health risk and a fire danger that’s tough to spot until something has gone wrong.
Personal Experience With Careful Handling
From years working in a college chemistry lab, I remember early lessons about safety gear with chemicals like this one. Even if you’ve gone through these motions a thousand times, having goggles, gloves, and a proper coat makes the difference between a normal workday and an accident you never forget. Splashing this stuff on your hands doesn’t burn at first, but within minutes, the skin feels raw. If you get it in your eyes, you’ll be rushing to the eyewash station and hoping for no lasting damage. Most folks forget about inhalation, though—vapors sneak up while you’re focused on pouring or weighing, so investing in a decent fume hood always made sense.
Smart Storage and Ventilation
A surprising number of incidents start with bad storage choices. Keeping 4-Bromotoluene backed up against acids or oxidizers is an accident writing itself. Findings from the Chemical Safety Board show most chemical fires and exposures happen after-hours, long after everyone’s gone home. Stashing this chemical in a well-labeled, tightly-sealed bottle away from sunlight and anything reactive takes a minute, but saves hours of cleanup or paperwork. Ventilation goes hand-in-hand with storage. A room packed with chemicals and no working fume hood ends up spreading vapors everywhere. Inspecting that ventilation stays clear and runs properly works almost better than any written protocol.
Health Risks: Not Just a Lab Problem
Working with 4-Bromotoluene outside a research setting brings a different kind of risk. Sometimes students or new hires treat it like standard lab solvents. Inhaling even a little can start headaches, dizziness, or nausea. Studies published by NIOSH point out that people exposed over months develop long-term problems with breathing and skin sensitivity. Getting chemicals on gloves and then touching your phone or face messes with your health in ways that pile up. I’ve seen friends who used to skip gloves now dealing with eczema and chemical burns.
Cleaning Up Minor and Major Spills
Minor spills seem easy to wipe up, but 4-Bromotoluene leaves an oily residue and a smell that clings to clothes. Using paper towels or rags just spreads it around. Granular absorbents and sealed disposal bags beat shortcuts every time. After any spill bigger than a few drops, reporting it and clearing people out gives everyone a shot at staying healthy. No one likes dragging the safety officer in, but nothing ruins a week faster than a chemical mishap ignored until it’s too late.
Building a Culture of Preparedness
Well-established labs and workplaces build habits through training, drills, and clear communication. Walking through a new workspace together, checking labels, and reviewing emergency plans turns strangers into teammates. Safety data sheets shouldn’t just sit in a drawer. Reviewing them regularly means you’re not digging for answers during a real emergency. As more workplaces follow OSHA and ACS best practices, they’ve seen injuries drop and productivity improve—because trust and safety aren’t add-ons, they run straight through daily routines.
Better Habits, Safer Outcomes
Chemical safety doesn’t rest on lucky days or tough attitudes. Every lab partner or technician cutting corners puts someone else’s health on the line. Using protective gear, labeling bottles clearly, locking up incompatible substances, and practicing honest cleanup after any spill creates a safer environment for everyone. Hard lessons shape strong habits. The real professionals don’t bluff or joke when it comes to handling 4-Bromotoluene—they prepare before problems ever show up.
Describing Its Physical Appearance
Ask a chemist to show you 4-Bromotoluene in its raw state, and you’ll likely be staring at a clear, colorless liquid in a small glass vial. This compound, known for its straightforward structure — a bromine atom hugging a methyl-substituted benzene ring — doesn’t bother putting on any dramatic colors or unique textures. Even with years spent in university labs, you don’t spot much difference between this liquid and the water used to rinse glassware, except for the faint, sweet, almost medicinal odor drifting from the open vial. Synthetic chemists recognize this smell, sharp on the nose and sticking to lab coats long after leaving the fume hood.
Recognizing 4-Bromotoluene in the Lab
To an untrained eye, 4-Bromotoluene doesn’t grab attention. No hint of yellow or brown taints its appearance. Under ambient temperatures, it's a liquid, not a powder or a crystalline solid. The moment you dip a clean glass rod or watch glass into it, greasy slick beads form and evaporate slowly, reminding you more of organic solvents than anything water-based. Safety data sheets repeat the same observations: clear, colorless, and flammable — not the sort of chemical that gives away any secrets visually.
Why Accuracy About Appearance Matters
Anyone working with chemicals knows assumptions cause trouble. I remember a time during my graduate research when a simple mix-up between similar-looking liquids slowed a synthesis project by several days. Documenting each chemical’s appearance — right down to its clarity and viscosity — cuts confusion, especially if shelf labels peel off or you inherit unmarked bottles. In the industrial sector, where 4-Bromotoluene takes on a role as a building block for dyes and pharmaceuticals, misidentification can lead to wasted raw materials and regulatory red tape. Due diligence in describing what you pour from a bottle stops problems before they start.
Supporting Evidence From Industry and Research
Published material from chemical suppliers and technical handbooks backs up what you see firsthand. Sigma-Aldrich, Alfa Aesar, and similar catalogs all describe 4-Bromotoluene as a colorless liquid at room temperature, with a boiling point hovering around 184°C. These details line up with direct lab experience and the collective memory of generations of chemists. No one has reported finding colored crystals or cloudy mixtures from a fresh bottle of this compound — clear, colorless liquid remains the standard, as confirmed through quality control checks and precise spectroscopic analysis.
Potential Issues and Thoughts on Reducing Risks
Chemical purity can’t be guessed by looks alone. Even the slightest bit of contamination could spoil a batch headed for sensitive pharmaceutical synthesis. Using reliable sources, storing bottles tightly closed away from light, and inspecting for any cloudiness or strange tint before use all reduce risk. In education and research, regular training keeps lab members alert for subtle signs of degradation. Combining clear, practical documentation with formal identification methods, like thin-layer chromatography or NMR, removes any lingering shadow of doubt about what sits in that bottle.
Why Proper Handling Really Matters
4-Bromotoluene shows up as a clear liquid most often used in labs, especially for making pharmaceuticals and specialty chemicals. Sometimes it looks pretty harmless, but trust me, it can give you more trouble than you bargained for. As someone who’s worked in chemical storage facilities, I’ve seen what happens when folks underestimate a material that seems like “just another aromatic compound.”
This chemical catches fire more easily than water boils and releases vapors that can mess with your lungs or skin. In fact, inhaling those fumes over time has a way of making headaches, dizziness, and even respiratory irritation a regular feature of your workday.
Choosing the Right Storage Setup
You want to put 4-Bromotoluene in tightly sealed containers, preferably glass, stainless steel, or high-density polyethylene. Ordinary plastic never cuts it because this stuff can eat its way right through. Containers should never sit under direct sunlight or near heat sources.
From my own time in a chemical storeroom, one simple misstep always stood out: storing volatile solvents next to oxidizers. That move gives you a front-row seat to dangerous reactions that could have been avoided by putting good margin between incompatible classes. For 4-Bromotoluene, keep it far from oxidizing agents or anything acidic. Store it only on shelves designed for flammable materials, with spill containment in place.
Taking Control of the Environment
The air in a storage room should hang around room temperature, and humidity must stay low. Even a little warmth can make those vapors ramp up fast. Well-ventilated spaces are non-negotiable; never stash containers in a closet or other cramped zone. The smell of strong solvents in a closed space tells you all you need to know about the risks.
Every workplace I know with a spotless safety record runs regular inspections for leaks, corrosion, or damaged seals. If anything looks off, they replace the container or move the chemical right away. Emergency showers and eyewash stations need to sit within a few paces, not at the far end of the building.
Getting Transportation Right
Moving this liquid from one place to another means double-checking every step. The DOT labels it as a hazardous material. Regulations call for special labeling, accident-proof packaging, and paperwork describing what’s inside the truck or shipping container. Forgetting even one step leads to serious legal headaches and, more importantly, endangers everyone on the road.
The best-run companies use trained drivers who don’t treat hazardous cargo like a regular parcel. Hazmat placards go on all four sides of the truck. Shipments should be kept away from other cargo, especially oxidizers or acids, just like in the storeroom.
What Works for Long-Term Safety
Start by training every worker on what 4-Bromotoluene can do if spilled or inhaled. Keep the safety data sheet in plain sight. Personal protective gear, like chemical splash goggles and gloves rated for organic solvents, never goes ignored on my watch.
From my end, I found that regular safety drills keep people prepared for spills or fires, which happen less often when everyone respects the risks and follows the rules. Real-world experience tells us: shortcuts and “good enough” measures bring trouble. Invest time in better training, keep up with maintenance on storage spaces, and you’ll minimize accidents.
Safe storage and transport of 4-Bromotoluene require vigilance, not just a checklist. Human attention, responsible systems, and the willingness to go beyond the bare minimum make safety more than just a buzzword.
| Names | |
| Preferred IUPAC name | 1-Bromo-4-methylbenzene |
| Other names |
p-Bromotoluene
1-Bromo-4-methylbenzene 4-Methylbromobenzene |
| Pronunciation | /ˈfɔːrˈbroʊ.moʊ.tɒl.juːiːn/ |
| Identifiers | |
| CAS Number | 106-38-7 |
| Beilstein Reference | 1209227 |
| ChEBI | CHEBI:14209 |
| ChEMBL | CHEMBL14242 |
| ChemSpider | 10875 |
| DrugBank | DB03841 |
| ECHA InfoCard | 03b75b24-9ccc-4753-bd74-2d8a319e7d52 |
| EC Number | 202-851-5 |
| Gmelin Reference | 82122 |
| KEGG | C14420 |
| MeSH | D000384 |
| PubChem CID | 7227 |
| RTECS number | XS9625000 |
| UNII | M6K24MS7EE |
| UN number | UN2517 |
| CompTox Dashboard (EPA) | 4-Bromotoluene: "DTXSID4020103 |
| Properties | |
| Chemical formula | C7H7Br |
| Molar mass | 185.04 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Odor | Aromatic |
| Density | 1.397 g/mL at 25 °C |
| Solubility in water | Insoluble |
| log P | 3.9 |
| Vapor pressure | 0.4 mmHg (at 25°C) |
| Acidity (pKa) | 42.5 |
| Magnetic susceptibility (χ) | -60.0·10⁻⁶ cm³/mol |
| Refractive index (nD) | 1.546 |
| Viscosity | 0.889 cP (20°C) |
| Dipole moment | 1.72 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 336.6 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | -4.2 kJ/mol |
| Std enthalpy of combustion (ΔcH⦵298) | -4817.2 kJ/mol |
| Hazards | |
| GHS labelling | GHS02, GHS07 |
| Pictograms | GHS07 |
| Signal word | Warning |
| Hazard statements | H315, H319, H335 |
| Precautionary statements | P210, P261, P280, P305+P351+P338, P337+P313 |
| NFPA 704 (fire diamond) | The NFPA 704 (fire diamond) for 4-Bromotoluene is: **"2-2-0"** |
| Flash point | 64 °C |
| Autoignition temperature | 457°C |
| Lethal dose or concentration | LD50 Oral Rat 3270 mg/kg |
| LD50 (median dose) | LD50 (median dose) Oral Rat: 6800 mg/kg |
| NIOSH | CN9475000 |
| PEL (Permissible) | Not established |
| REL (Recommended) | Room Temperature |
| Related compounds | |
| Related compounds |
Bromobenzene
4-Iodotoluene 4-Chlorotoluene Benzyl bromide p-Xylene |
