MSDS for 4-Bromochlorobenzene

Identification

Product Name: 4-Bromochlorobenzene
Chemical Formula: C6H4BrCl
CAS Number: 106-39-8
Synonyms: p-Bromochlorobenzene, 1-Bromo-4-chlorobenzene
Recommended Uses: Laboratory chemicals, organic synthesis intermediates
Supplier Information: Manufacturers and distributors specializing in fine chemicals, contact information provided upon purchase, emergency contact listed directly on product bottle and technical sheet.
Emergency Telephone: National poisons information service or local emergency response center.

Hazard Identification

Classification: Acute toxicity (oral, dermal), Eye irritation, Possible skin irritant
Label Elements: Pictograms of exclamation mark for warning
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes moderate eye irritation, may cause skin irritation and respiratory tract discomfort.
Precautionary Statements: Wash hands thoroughly after handling, avoid eating, drinking, or smoking during use, wear protective gear to lessen risk, use only outdoors or in well-ventilated area, avoid breathing dust or vapor.
Other Hazards: Chemical may create hazardous decomposition products if heated or exposed to incompatible substances; dust possibility in handling may irritate upper respiratory passages.

Composition / Information on Ingredients

Chemical Name: 4-Bromochlorobenzene
Concentration: ≥99% (as supplied for laboratory or industrial use)
Impurities: Trace halogenated organic compounds exceptionally low as per analytical certificate
Other Constituents: None listed outside standard purification process residues
EC Number: 203-391-0

First Aid Measures

Inhalation: Move affected person to fresh air immediately, keep comfortable for breathing, consult medical advice if symptoms persist, support respiratory function if needed.
Skin Contact: Remove any contaminated clothing, wash exposed skin thoroughly with plenty of water and mild soap, seek medical attention for irritation that does not improve quickly.
Eye Contact: Rinse cautiously under a gentle stream of clean water for several minutes, remove contact lenses if used and safe to do so, continue rinsing, refer for medical examination if irritation persists.
Ingestion: Rinse mouth, never induce vomiting, offer water if victim is conscious, get prompt medical assistance or contact poison control service.
Symptoms: Respiratory discomfort, mild to moderate eye and skin irritation, gastrointestinal upset if swallowed.

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical powder, CO2, alcohol-resistant foam, water spray for larger fires
Unsuitable Media: Direct water jet may spread contaminated material
Special Exposure Hazards: Hydrogen chloride, bromide, and phosgene formation by product combustion in fire
Protective Equipment: Self-contained breathing apparatus and full protective fire gear strongly recommended
Specific Fire-Fighting Procedures: Isolate hazard area, remove containers from fire zone if safe, cool with water mist to prevent pressure build-up
Fire/Explosive Properties: Product is not highly flammable but may sustain combustion with strong heat, vapors heavier than air, collect in low areas.

Accidental Release Measures

Personal Precautions: Ventilate area, avoid dust formation, minimize inhalation, wear gloves, protective suit, and suitable eye/face protection
Environmental Precautions: Prevent infiltration to drains, surface water, or soil, notify environmental authorities for spills above reportable quantities
Methods for Containment and Cleaning: Sweep up without generating dust, shovel into properly labeled chemical waste container; rinse area with copious water after removal, ventilate closed spaces thoroughly
Decontamination: Scrub contaminated surfaces with soapy water, secure debris for chemical disposal, avoid direct contact
Emergency Procedures: Restrict area, restrict unnecessary personnel, consult safety officer or supervisor.

Handling and Storage

Handling: Avoid breathing dust, vapor, or mist; use only in a chemical fume hood, wear chemical resistant gloves and lab coat; avoid contact with skin and eyes; practice good hygiene and cleanliness; use dedicated tools to prevent cross-contamination
Safe Storage: Keep containers tightly closed and stored at room temperature in a cool, dry, well-ventilated area, away from incompatible substances such as oxidizers and strong bases
Special Considerations: Store away from heat sources and out of direct sunlight, label all containers clearly, keep away from foodstuffs or animal feed
Technical Precautions: Use antistatic systems where stored in bulk to prevent dust-related ignition

Exposure Controls and Personal Protection

Engineering Controls: Handle with local exhaust ventilation or in a fume hood, provide eyewash facilities and emergency shower where significant exposure potential exists
Personal Protective Equipment: Chemical splash goggles, nitrile gloves, lab coat or chemical-resistant apron, particulate respirator (P3 or NIOSH-approved equivalent) for dust-generating activities
Occupational Exposure Limits: No specific exposure limit set by OSHA, ACGIH, or NIOSH due to limited widespread commercial use, general nuisance dust limits apply
Hygiene Measures: Wash hands, forearms, and face after handling, separate from clean areas, remove contaminated clothing after use

Physical and Chemical Properties

Appearance: White to faintly off-white crystalline powder
Odor: Mild aromatic
Odor Threshold: Not established
pH: Not applicable (insoluble in water)
Melting Point: 63-67°C (145-153°F)
Boiling Point: 220-223°C (428-433°F)
Flash Point: >113°C (235°F) (closed cup)
Evaporation Rate: Not established
Flammability: Not considered highly flammable under normal use
Vapor Pressure: Low under ambient conditions
Solubility: Insoluble in water, soluble in organic solvents (ethanol, ether, chloroform)
Vapor Density: Heavier than air
Relative Density: 1.6-1.7 (water=1)
Partition Coefficient (log Kow): 3.93 (predicted)
Decomposition Temperature: >250°C (482°F)
Viscosity: Not applicable as solid

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling conditions
Potential Hazardous Reactions: May react with strong oxidizing agents or bases
Conditions to Avoid: Excessive heat, sparks, open flames, moisture
Incompatible Materials: Strong oxidizers such as peroxides, nitric acid, alkali metals, strong bases
Hazardous Decomposition Products: Hydrogen chloride, bromide gases, phosgene (thermal decomposition, fire scenarios)
Polymerization: Does not undergo hazardous polymerization

Toxicological Information

Likely Routes of Exposure: Inhalation, skin and eye contact, accidental ingestion
Acute Toxicity: Oral LD50 (rat) >300 mg/kg reported, low to moderate hazard, not acutely lethal in expected workplace concentrations
Skin Corrosion/Irritation: May cause slight to moderate irritation
Serious Eye Damage/Irritation: Causes mild irritation
Respiratory Sensitization: Sensitization reactions uncommon, but avoid repeated inhalation
Mutagenicity: No evidence reported in standard in-vivo or in-vitro assays
Carcinogenicity: Not listed by IARC, NTP, OSHA as a known carcinogen
Specific Target Organ Toxicity (Single Exposure): Respiratory tract irritation possible
Specific Target Organ Toxicity (Repeated Exposure): Not well defined due to limited use
Other Data: Prolonged skin exposure may result in redness, dryness, or mild dermatitis

Ecological Information

Ecotoxicity: Harmful to aquatic life in concentrated spills, toxic to fish and aquatic invertebrates at higher levels, risk of long-term adverse effects in the aquatic environment
Persistence and Degradability: Slow degradation in soil and water, halogenated aromatic structure resists rapid breakdown
Bioaccumulative Potential: May bioaccumulate in organisms due to moderate log Kow, persistence in sediment likely
Mobility in Soil: Low solubility and strong binding to organic matter mean low overall mobility
Other Adverse Effects: Microbial degradation in natural waters limited, volatilization unlikely due to physical properties, always avoid uncontrolled releases.

Disposal Considerations

Waste Disposal: Collect and store securely in labeled, compatible chemical waste containers; do not pour down drains or mix with municipal waste
Contaminated Packaging: Triple-rinse and manage as hazardous waste after use, observe local and national disposal regulations
Methods of Disposal: Incinerate through licensed chemical hazardous waste contractor, consult local authority for approved incineration facility
Special Precautions: Never attempt informal burning or landfill disposal; spill residues, wipes, gloves, and other contaminated items handled as hazardous

Transport Information

UN Number: 3077
UN Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (4-Bromochlorobenzene)
Transport Hazard Class(es): 9 (Miscellaneous dangerous substances)
Packing Group: III (substances presenting low danger)
Environmental Hazards: Marine pollutant as designated by IMDG, not permitted for air transport without special packaging
Transport Labels Required: Class 9 label, marine pollutant mark for international shipments
Special Transport Precautions: Secure packaging to prevent spillage, avoid excessive stacking or mechanical stress, consult logistic provider for mode-specific requirements.

Regulatory Information

TSCA (United States): Listed
DSL/NDSL (Canada): Listed
REACH (EU): Registered or pre-registered, subject to applicable restrictions
SARA Title III: Not specifically listed as extremely hazardous but significant quantities may be subject to reporting
California Proposition 65: Not listed
WHMIS Classification (Canada): Not classified under specific hazard categories but treated as general laboratory chemical hazard
Additional Regulations: Subject to chemical inventory management, handling reporting in several jurisdictions. Always check workplace regulatory updates for product-specific advisories.