Material Safety Data Sheet: 2-Ethylhexyl Bromide

Identification

Product Name: 2-Ethylhexyl Bromide
Chemical Formula: C8H17Br
Synonyms: 1-Bromo-2-ethylhexane
CAS Number: 18908-66-2
Intended Use: Commonly used as an alkylating reagent and intermediate in organic synthesis
Manufacturer Contact: Manufacturer’s name, 24-hour emergency phone number, mailing address
Recommended Use: Industrial, laboratory
Restrictions: Not for food or pharmaceutical use, not suitable for consumer products

Hazard Identification

Classification: Flammable liquid, irritant, health hazard
Label Symbols: Flame, exclamation mark, health hazard pictograms
Signal Word: Danger
Hazard Statements: Causes eye, skin, and respiratory irritation. Harmful if swallowed or inhaled. May damage organs through prolonged or repeated exposure.
Precautionary Statements: Avoid skin contact, avoid breathing vapors or mist, use only outdoors or in well-ventilated area, keep away from heat and open flames
Possible Symptoms: Coughing, skin redness, headache, dizziness, eye irritation
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Emergency Overview: Clear, colorless, volatile liquid with strong odor. Vapor may cause drowsiness.

Composition / Information on Ingredients

Chemical Name: 2-Ethylhexyl Bromide
Common Name: 1-Bromo-2-ethylhexane
CAS Number: 18908-66-2
Synonyms: 2-Ethylhexane bromide
Impurities: Possible traces of related alkyl bromides
Purity: >98%
Other Components: No significant stabilizers or additives reported

First Aid Measures

General Measures: Move individual away from exposure, ensure airway and breathing
Inhalation: Remove to fresh air, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, flush exposed skin with soap and water for 15 minutes, seek medical advice for ongoing irritation
Eye Contact: Rinse eyes immediately with plenty of water for at least 15 minutes, seek immediate ophthalmologic assessment
Ingestion: Rinse mouth with water, do not induce vomiting, get immediate medical attention
Indications for Immediate Medical Attention: Severe respiratory distress, persistent irritation, or loss of consciousness
Self-Protection for First Aiders: Gloves, eye protection, avoid contact with contaminated clothes and area

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam
Inappropriate Media: Direct water stream may spread burning liquid
Specific Hazards: Produces carbon oxides, hydrogen bromide, and toxic vapors under fire
Protective Equipment: Self-contained breathing apparatus, full protective gear
Special Instructions: Remove containers from fire area if safe, cool with water spray, prevent runoff into drains
Fire Hazards: Vapors heavier than air, may travel and ignite from distant ignition sources
Explosion Potential: Vapors may form explosive mixtures with air

Accidental Release Measures

Personal Precautions: Avoid contact with skin and eyes, wear chemical-resistant gloves, goggles and protective clothing
Protective Equipment: Respirators for poor ventilation, chemical splash suit for large spills
Environmental Precautions: Do not allow into drains, water courses, or soil. Prevent further leakage.
Cleanup Methods: Ventilate area, use inert absorbent material such as vermiculite to collect spill, transfer to labeled disposal containers
Additional Guidance: Wash area with plenty of water after material pick-up, collect contaminated cleaning material for disposal

Handling and Storage

Handling Precautions: Use only in well-ventilated areas, avoid inhalation and contact with skin and eyes, avoid sources of ignition
Technical Measures: Electrically ground and bond containers and equipment
Hygiene Measures: Wash hands thoroughly before meals and after handling
Storage Requirements: Keep in tightly closed, compatible container, store in a cool, dry, well-ventilated area away from incompatible substances (strong oxidizers, acids, bases)
Incompatible Materials: Alkali metals, strong oxidizing agents, sources of ignition
Storage Conditions: Protect from moisture, sunlight, temperature extremes, store separately from food and feed

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established limits for 2-Ethylhexyl Bromide; apply general nuisance vapor limits
Control Measures: Use local exhaust ventilation, fume hood, or process enclosure
Personal Protective Equipment: Chemical-resistant gloves (nitrile, neoprene), splash-proof goggles, lab coat or apron
Respiratory Protection: Approved respirator for organic vapors, if engineering controls are inadequate
Eye / Face Protection: Tight-fitting goggles or face shield
Hand Protection: Avoid absorption through latex, use thicker barrier gloves
General Safety Practices: No eating, drinking, or smoking in area of use, change contaminated clothing

Physical and Chemical Properties

Appearance: Clear, colorless liquid
Odor: Strong, characteristic
Melting Point / Freezing Point: Estimated -60°C
Boiling Point: About 198–200°C
Relative Density: Roughly 1.18–1.20 g/cm³ at 20°C
Solubility: Insoluble in water, soluble in ethanol and most organic solvents
Vapor Pressure: Moderate at room temperature
Flash Point: 77°C (closed cup)
Auto-ignition Temperature: 420°C
Explosive Properties: Vapors may cause explosive air-vapor mixtures
Partition Coefficient (log Pow): Predicted 4.5–5.5 (lipophilic)
Evaporation Rate: Not fast, but forms significant vapor at room temperature

Stability and Reactivity

Chemical Stability: Stable under normal use conditions
Conditions to Avoid: Exposure to heat, open flame, strong sunlight, static discharge
Materials to Avoid: Strong oxidizers, nitric acid, alkali metals
Reactivity: Reacts with strong bases and nucleophiles, releases hydrogen bromide on decomposition
Hazardous Decomposition Products: Carbon oxides, hydrogen bromide gas, unidentified organic fumes
Polymerization: Not known to polymerize under standard conditions

Toxicological Information

Likely Routes of Exposure: Inhalation, skin, eye, ingestion
Acute Toxicity: Harmful if inhaled or ingested; LD50 (oral/rat): Data limited, estimated moderate toxicity
Skin Corrosion / Irritation: Causes skin redness and irritation on contact
Eye Damage / Irritation: Causes moderate to severe irritation; prolonged contact can result in injury
Respiratory Sensitization: May cause coughing, shortness of breath
Chronic Effects: Prolonged exposure may affect liver and nervous system
Other Effects: Headache, dizziness, drowsiness at higher vapor concentrations
Carcinogenicity / Mutagenicity / Reproductive Toxicity: Data on long-term risks limited, no evidence of carcinogenicity found to date

Ecological Information

Ecotoxicity: Harmful to aquatic life, may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Not readily biodegradable, may persist in soil and water
Bioaccumulative Potential: Potential to bioaccumulate due to high log Kow
Mobility in Soil: Low water solubility, likely to adsorb to organic material
Other Adverse Effects: Discharge to environment may have immediate or delayed harmful effects on aquatic organisms
Avoid Release: Avoid contamination of ground and surface waters at all costs

Disposal Considerations

Disposal Methods: Dispose of as hazardous organic waste, incinerate in licensed chemical incinerator with afterburner and scrubber
Container Disposal: Rinse empty containers, puncture and send to hazardous waste facility
Additional Recommendations: Do not dispose of in household garbage, do not flush into sewer, comply with federal, provincial, or local regulations
Contaminated Packaging: Treat as hazardous waste, reuse or recycle whenever safe and permitted

Transport Information

UN Number: 1993 (Flammable liquid, n.o.s., containing 2-Ethylhexyl Bromide)
UN Proper Shipping Name: Flammable liquid, n.o.s.
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: III
Marine Pollutant: Yes, based on ecotoxicity
Special Transport Precautions: Secure and separate from incompatible goods, shipping containers must be leak-proof, emergency response guide available during transport
Label Requirements: Flammable liquid, Marine pollutant

Regulatory Information

International Inventories: Listed on TSCA, REACH, or equivalent regulatory inventories in major jurisdictions
US Regulations: Subject to SARA Title III Sec 313 reporting as an organic bromide. Not classified under Proposition 65, but check state requirements
EU Classification: Hazard statements per CLP: H315, H319, H335
Label Requirements: Hazard pictograms, GHS-compliant labels
Workplace Exposure Regulations: Follow OSHA, ACGIH guidelines for hazardous chemicals
Other Regulatory Listings: Chemical may appear on local environmental hazard or water pollution lists
References: Consult latest national chemical safety legislation and local regulatory agency publications