2-Cyanophenol MSDS

Identification

Name: 2-Cyanophenol
Chemical Formula: C7H5NO
CAS Number: 611-20-1
Synonyms: o-Cyanophenol, 2-Hydroxybenzonitrile
Molecular Weight: 119.12 g/mol
Recommended Use: Intermediate for organic synthesis, research, laboratory chemical
Manufacturer/Supplier Details: Chemical supplier’s address, emergency contact number
Product Code: As per supplier’s internal coding

Hazard Identification

GHS Classification: Acute toxicity (oral, dermal, inhalation), skin irritation, serious eye damage
Signal Word: Danger
Hazard Statements: Harmful if swallowed, causes skin irritation, causes serious eye damage
Pictograms: Exclamation mark, Corrosion
Precautionary Statements: Avoid breathing dust, wear protective equipment, wash hands thoroughly after handling
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Possible Health Effects: Headache, dizziness, eye burns, gastrointestinal discomfort

Composition / Information on Ingredients

Substance: 2-Cyanophenol
Purity: ≥98%
Common Impurities: Trace moisture, residual solvents from manufacturing
Other Names: o-Hydroxybenzonitrile
EC Number: 210-256-8
Relevant Identified Uses: Organic synthesis, chemical research

First Aid Measures

Inhalation: Move person to fresh air, monitor for respiratory distress, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash affected skin with plenty of soap and water for at least 15 minutes, seek medical advice if irritation develops
Eye Contact: Rinse eyes with clean water for at least 20 minutes, remove contact lenses if present and easy, keep eyelids apart, seek immediate medical attention
Ingestion: Rinse mouth, do not induce vomiting, give small amount of water, seek immediate medical attention
Delayed Symptoms: Nausea, dizziness, persistent irritation
Advice for Doctors: Treat symptomatically, monitor vital signs, consider observation for delayed pulmonary edema and neurological effects

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, alcohol-resistant foam, water spray
Unsuitable Media: Direct water jet
Hazards from Combustion: Emits toxic gases (carbon oxides, nitrogen oxides, cyanide compounds)
Protective Equipment: Firefighters must wear self-contained breathing apparatus, full chemical protective clothing
Special Procedures: Move containers away from fire if safe, avoid inhaling combustion fumes, cool containers with water fog
Explosion Hazards: Dust can form explosive mixtures with air

Accidental Release Measures

Personal Precautions: Evacuate unnecessary personnel, provide adequate ventilation, use personal protective equipment including gloves and respirator
Environmental Precautions: Do not release into drains, prevent further leakage or spillage if safe to do so, notify relevant authorities in event of significant spill
Methods for Clean-Up: Contain and collect material with non-combustible absorbent (sand, earth), transfer to suitable, labeled disposal containers, wash spill area with water
Decontamination: Ventilate area, avoid raising dust, thoroughly clean equipment used in handling
Advice for Emergency Responders: Wear positive pressure self-contained breathing apparatus and protective suit

Handling and Storage

Handling: Use in a well-ventilated area, avoid contact with skin and eyes, avoid inhalation of dust or fumes, do not eat, drink, or smoke while handling, wear appropriate PPE
Storage: Keep container tightly closed, store in dry, cool, well-ventilated location away from incompatible substances (strong oxidizing agents, strong acids and bases), protect from moisture and direct sunlight
Special Storage Conditions: Separate from food and drink, use anti-static measures, avoid sources of ignition
Incompatible Materials: Strong oxidizers, acids, alkalis

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established limit for 2-cyanophenol, control exposure to minimize risks
Engineering Controls: Local exhaust ventilation, chemical fume hood, emergency eyewash and shower facilities
Respiratory Protection: Dust mask or NIOSH-approved respirator for particulates
Skin Protection: Chemical-resistant gloves (nitrile, neoprene), lab coat
Eye Protection: Chemical safety goggles, face shield
Work Hygiene: Remove contaminated clothing before entering eating areas, wash hands before breaks and after work
Environmental Exposure Controls: Avoid release into the environment, monitor effluent

Physical and Chemical Properties

Appearance: Off-white to pale yellow solid (crystals or powder)
Odor: Faint, characteristic
Odor Threshold: Not established
pH: Not available (insoluble in water)
Melting Point/Freezing Point: 112–115°C
Boiling Point/Range: 221–224°C (decomposes)
Flash Point: 121°C (closed cup)
Evaporation Rate: Not determined
Flammability (solid, gas): May be combustible at high temperature
Vapor Pressure: Very low at 20°C
Relative Density: 1.16 (water = 1)
Solubility: Slightly soluble in water, soluble in ethanol and ether
Partition Coefficient (n-octanol/water): Log Kow ~1.25
Auto-ignition Temperature: Not determined
Decomposition Temperature: >230°C
Viscosity: Not applicable (solid)
Particle Characteristics: Powder or crystalline

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling
Hazardous Reactions: May react with strong oxidizers, acids, and bases
Conditions to Avoid: Excessive heat, open flame, direct sunlight, moisture
Incompatible Materials: Strong oxidizing agents, strong acids, strong bases
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, hydrogen cyanide, nitrogen oxides
Polymerization: Will not occur under normal conditions

Toxicological Information

Acute Toxicity (Oral): Harmful if swallowed, LD₅₀ (rat): ~100-250 mg/kg
Acute Toxicity (Inhalation): Data not available, expect harmful effects similar to ingestion
Acute Toxicity (Dermal): May be harmful, skin penetration possible
Skin Corrosion/Irritation: Causes skin irritation, redness, and discomfort on contact
Eye Damage/Irritation: Causes serious eye damage, risk of chemical burns
Respiratory Sensitization: No specific data, possible irritation
Germ Cell Mutagenicity: No evidence available
Carcinogenicity: Not classified as carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: No data available
STOT-single exposure: May cause drowsiness, headaches, nausea
STOT-repeated exposure: Not established
Aspiration Hazard: Not a risk under normal use

Ecological Information

Aquatic Toxicity: Expected to be harmful to aquatic life
Persistence and Degradability: Not readily biodegradable, remains stable in the environment for extended periods
Bioaccumulative Potential: Low potential based on Log Kow value
Mobility in Soil: Low to moderate mobility, may leach to groundwater in certain conditions
Other Adverse Effects: Toxic to some aquatic organisms, avoid uncontrolled release
Ecotoxicological Data: No detailed LC₅₀ values published for 2-cyanophenol; treat as chemical of concern

Disposal Considerations

Waste Disposal Methods: Dispose of in accordance with local, regional, national, and international regulations; incineration recommended for small amounts
Contaminated Packaging: Thoroughly clean containers before disposal or send for proper recycling, offer cleaned packaging to approved waste collectors
Disposal Precautions: Do not dispose of into surface water, ground water, or sewers
Other Information: Do not mix with other waste streams, keep detailed records of disposal

Transport Information

UN Number: Not classified under UN dangerous goods list
Proper Shipping Name: 2-Cyanophenol
Transport Hazard Class: Not regulated for ground, air, or sea
Packing Group: No packing group assigned
Labeling Requirements: None mandated, but chemical name should appear on package
Special Precautions: Ensure package integrity, avoid physical shocks

Regulatory Information

TSCA (USA): Listed
DSL/NDSL (Canada): Listed
REACH (EU): Pre-registered, check registration status for tonnage bands
Other National Inventories: Included in most regional databases
OSHA (USA): Not specifically regulated, general chemical safety applies
Risk Phrases: R22 (harmful if swallowed), R36/38 (irritating to eyes and skin)
Safety Phrases: S22 (do not breathe dust), S24/25 (avoid contact with skin and eyes)
Other Regulations: Subject to workplace chemical control rules, hazardous communication standards