Material Safety Data Sheet: 2-Chloropropane

Identification

Product Name: 2-Chloropropane
Synonyms: Isopropyl chloride, 1-methylethyl chloride
Chemical Formula: C3H7Cl
Molecular Weight: 78.54 g/mol
CAS Number: 75-29-6
Recommended Use: Industrial solvent, chemical intermediate
Supplier Information: Manufacturer contact details and emergency telephone contact available on request

Hazard Identification

Classification: Flammable liquid, acute toxicity (inhalation and oral), skin and eye irritant, specific target organ toxicity
GHS Label Elements: Flame symbol, exclamation mark
Signal Word: Danger
Hazard Statements: Highly flammable liquid and vapor; harmful if inhaled or swallowed; causes eye and skin irritation; may cause respiratory tract irritation
Precautionary Statements: Avoid heat, sparks, open flame; avoid breathing vapors; use only outdoors or in a well-ventilated area; wear protective gloves, clothing, and eye/face protection; wash hands thoroughly after handling; keep container tightly closed

Composition / Information on Ingredients

Chemical Name: 2-Chloropropane
Concentration: ≥ 98%
Impurities: Traces of water, possible unreacted hydrocarbons
Identifiers: CAS 75-29-6
Other Components: None identified as hazardous below reporting thresholds

First Aid Measures

Inhalation: Remove person to fresh air immediately; seek medical attention if respiratory symptoms develop or persist; provide oxygen if breathing is difficult
Skin Contact: Wash thoroughly with soap and water for at least 15 minutes; remove contaminated clothing and shoes; obtain medical attention for persistent irritation
Eye Contact: Flush eyes with gentle stream of water for at least 15 minutes lifting eyelids occasionally; seek immediate medical help
Ingestion: Do not induce vomiting; rinse mouth with water; give water to drink if person is fully conscious and alert; do not administer anything by mouth to an unconscious person; obtain immediate medical attention
Notes to Physician: Treat symptomatically and supportively; monitor respiratory and cardiovascular function; risk of chemical pneumonitis from aspiration

Fire-Fighting Measures

Suitable Extinguishing Media: Use carbon dioxide, dry chemical, or alcohol-resistant foam to extinguish fires; water spray can be used to cool fire-exposed containers
Unsuitable Extinguishing Media: Do not use a direct water jet as it may spread the fire
Special Hazards: Forms hazardous combustion products including hydrogen chloride, carbon monoxide, phosgene at high temperatures; vapors are heavier than air and may travel to ignition sources
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear; approach fire from upwind; use water spray to keep fire-exposed containers cool
Advice: Eliminate all ignition sources and evacuate area; prevent runoff to sewers or water sources

Accidental Release Measures

Personal Precautions: Evacuate unnecessary personnel from area; ensure adequate ventilation; avoid breathing vapors; don chemical resistant gloves, goggles, and clothing
Environmental Precautions: Prevent further leakage or spillage if safe; avoid release to soil, drains, surface and groundwater
Containment Methods: Dike spillage using inert materials like sand or earth; do not use combustible material such as sawdust
Clean-Up Methods: Absorb with inert material, place in chemical waste container for disposal; decontaminate area with detergent and water; ventilate area and wash spill site after material pickup is complete

Handling and Storage

Handling: Use non-sparking tools; ground and bond containers; keep away from heat, sparks, flames, and other ignition sources; avoid inhalation and contact with skin and eyes; use in a chemical fume hood or well-ventilated space
Storage: Store in tightly closed containers in a cool, dry, well-ventilated area designated for flammable chemicals; keep away from incompatible substances such as strong oxidizers, acids, and alkalis; protect from sunlight and static discharge
Specific Measures: Ensure containers are labeled and inspected regularly for leaks or deterioration; segregate from non-compatible materials and foodstuffs

Exposure Controls and Personal Protection

Exposure Limits: OSHA PEL and ACGIH TLV not specifically established; use lowest feasible exposure
Engineering Controls: Local exhaust ventilation, general ventilation, use of explosion-proof electrical equipment
Personal Protective Equipment (PPE): Chemical splash goggles, face shield, flame-resistant gloves (nitrile or neoprene), lab coat or flame-resistant clothing, chemical-resistant apron, closed footwear
Respiratory Protection: Full facepiece air-purifying respirator with organic vapor cartridge or supplied air respirator for high exposure or insufficient ventilation
Hygiene Measures: Wash hands before breaks and after handling; no eating, drinking, or smoking in work areas; remove contaminated clothing after use

Physical and Chemical Properties

Appearance: Clear, colorless liquid
Odor: Sweet, ether-like
Odor Threshold: Not established
pH: Not applicable
Melting Point/Freezing Point: -120°C
Boiling Point/Range: 35.7°C (96.3°F)
Flash Point: -28°C (-18°F) (closed cup)
Evaporation Rate: High
Flammability: Highly flammable liquid and vapor
Explosion Limits: Lower: 2.4%; Upper: 13.2% (by volume in air)
Vapor Pressure: 463 mmHg @ 20°C
Vapor Density: 2.7 (air = 1)
Relative Density: 0.87 (water = 1)
Solubility: Slightly soluble in water; miscible with organic solvents
Partition Coefficient (n-octanol/water): log Kow 2.1
Auto-ignition Temperature: 510°C (950°F)
Decomposition Temperature: Data not available
Viscosity: Not applicable

Stability and Reactivity

Stability: Chemically stable under standard temperature and pressure; instability possible at elevated temperatures or in contact with incompatible materials
Conditions to Avoid: Heat, open flame, sparks, static electricity, sunlight
Incompatible Materials: Strong oxidizing agents, amines, alkali metals, strong bases, acids, aluminum
Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, carbon dioxide, phosgene
Hazardous Polymerization: Not expected to occur under recommended handling conditions

Toxicological Information

Acute Toxicity: LD50 (oral, rat): 900 mg/kg; LC50 (inhalation, rat, 4h): 12,500 ppm
Skin and Eye Irritation: Causes moderate irritation on contact; may cause redness, pain, temporary vision changes
Inhalation Risks: Inhalation can cause headache, dizziness, drowsiness, nausea, narcosis; high concentrations may result in CNS depression, unconsciousness
Chronic Effects: Prolonged or repeated exposure may cause liver, kidney, or central nervous system damage
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, OSHA, or ACGIH
Mutagenicity: Some animal test data suggest possible mutagenic effects
Sensitization: Not considered a skin or respiratory sensitizer
Other Effects: Repeated exposure may increase sensitivity to cardiac arrhythmias in the presence of adrenaline-like agents

Ecological Information

Ecotoxicity: Toxic to aquatic life; LC50 (fish, 96h): 28 mg/L; EC50 (daphnia, 48h): 10 mg/L
Persistence and Degradability: Not readily biodegradable; persists in environment, primarily by volatilization and slow hydrolysis
Bioaccumulation Potential: Moderate; log Kow indicates moderate potential for bioaccumulation
Mobility in Soil: May leach to groundwater due to volatility and low water solubility; mobility enhanced under certain conditions
Other Adverse Effects: Ozone layer depletion potential considered negligible; not classified as a greenhouse gas

Disposal Considerations

Waste Disposal Methods: Incinerate in a chemical incinerator equipped with afterburner and scrubber; follow all local, regional, and national regulations
Contaminated Packaging: Triple rinse containers; puncture or crush to prevent reuse; dispose as hazardous chemical waste
Precautions: Keep out of sewers, surface water, and soil; inform local environmental authorities of large spillages
Additional Guidance: Consult licensed professional waste disposal firm to ensure compliance

Transport Information

UN Number: 2358
UN Proper Shipping Name: Isopropyl chloride
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: II
Label: Flammable Liquid
Environmental Hazards: Marine pollutant (consult vessel's manifest or IMDG code)
Transport in Bulk: Governed by MARPOL Annex II procedures
Special Precautions: Avoid heat and ignition sources in transit; containers must be secured and properly labeled

Regulatory Information

TSCA: Listed on the U.S. Toxic Substances Control Act inventory
REACH: Registered under European REACH regulations
OSHA: Regulated as a hazardous chemical
SARA Title III: Subject to reporting under Section 311/312; not listed under Section 313
California Proposition 65: Not listed
Canadian DSL/NDSL: Listed
Other Country Inventories: Listed or notified as required by individual national regulations