Material Safety Data Sheet: 2-Chloroethyl-Benzene

Identification

Product Name: 2-Chloroethyl-Benzene
Synonyms: (2-Chloroethyl)benzene, Benzene, (2-chloroethyl)-, Phenyl Ethyl Chloride
CAS Number: 622-29-7
Recommended Use: Synthesis of organic chemicals, laboratory reagent
Supplier: Chemical distributor or manufacturer’s details on label
Emergency Contact: Refer to supplier’s emergency number
Manufacturer Address: Check Safety Data Sheet for current address

Hazard Identification

Classification: Flammable liquid, Acute toxicity (oral, dermal), Skin and eye irritation, Specific target organ toxicity
Signal Word: Danger
Hazard Statements: Causes skin irritation and serious eye irritation; May be harmful if swallowed or inhaled; May cause respiratory irritation; Flammable liquid and vapor
Pictograms: Flame, Exclamation Mark, Health Hazard
Precautionary Statements: Wear protective gloves, avoid breathing fumes and vapors, keep away from ignition sources, use only with adequate ventilation
Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Symptoms: Burning sensation, coughing, dizziness, nausea, headache

Composition / Information on Ingredients

Chemical Name: 2-Chloroethyl-Benzene
CAS Number: 622-29-7
Concentration: ≥98% (commercial grades), minor impurities as per batch specifications
Molecular Formula: C8H9Cl
Molecular Weight: 140.61 g/mol
Impurities: Trace amounts of benzene derivatives, chlorinated fragments as per manufacturing process

First Aid Measures

General Advice: Remove individual from exposure, seek medical attention
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, get medical help
Skin Contact: Take off contaminated clothing immediately, wash skin with plenty of soap and water, medical attention for persistent symptoms
Inhalation: Move to fresh air, keep at rest, support breathing as needed, consult a doctor
Ingestion: Rinse mouth, do not induce vomiting without medical advice, seek immediate medical attention
Important Symptoms: Redness, irritation, drowsiness, respiratory discomfort

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam, water spray (avoid direct jet of water)
Unsuitable Media: High pressure water jet
Specific Hazards: Vapors may form explosive mixture with air; releases toxic fumes under fire (hydrogen chloride, carbon monoxide)
Protective Equipment: Self-contained breathing apparatus, full protective suit
Special Precautions: Cool fire-exposed containers with water spray, avoid spreading material

Accidental Release Measures

Personal Precautions: Use personal protective equipment, ventilate area, eliminate ignition sources
Environmental Precautions: Prevent entry into sewers, watercourses, or soil
Spill Clean-up: Absorb with inert material (sand, earth), collect in appropriate containers for disposal, clean area with detergent and water, ventilate zone
Methods for Disposal: Dispose in accordance with regulatory requirements

Handling and Storage

Handling: Use in well-ventilated space, avoid contact with eyes, skin, and clothing, no eating or drinking while handling, ground containers to prevent static discharge
Storage: Store in tightly sealed container, cool, dry, and well-ventilated area, away from incompatibles (oxidizers, acids, bases), safe from heat, sparks, and open flame
Hygiene: Wash hands thoroughly after use, keep work clothes separate from other garments

Exposure Controls and Personal Protection

Occupational Exposure Limits: Not established for 2-chloroethyl-benzene; follow general chemical exposure limits
Engineering Controls: Local exhaust ventilation, fume hood, eye wash stations, safety showers
Respiratory Protection: NIOSH-approved respirator if exposure limits may be exceeded
Skin Protection: Impervious gloves (nitrile, neoprene), lab coat
Eye Protection: Chemical safety goggles, face shield as necessary
Environmental Exposure Control: Prevent emission to the environment, contain and collect spills quickly

Physical and Chemical Properties

Appearance: Colorless to pale yellow clear liquid
Odor: Aromatic, sharp odor
Boiling Point: 193–197°C
Melting Point: -42°C
Flash Point: 78°C (closed cup)
Autoignition Temperature: 435°C
Vapor Pressure: 0.5 mmHg at 25°C
Density: 1.04 g/cm³ at 20°C
Solubility: Insoluble in water, soluble in common organic solvents (ether, alcohol, benzene)
Viscosity: Not widely available, typically low
pH: Not applicable (neutral organic compound)

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling
Reactivity: May react with strong oxidizing agents, alkali metals, strong acids
Hazardous Reactions: May produce toxic gases (hydrogen chloride, carbon monoxide) on combustion or reaction with incompatible materials
Conditions to Avoid: Heat, flames, ignition sources, moisture
Incompatible Materials: Strong oxidizers, strong bases, acids
Polymerization: Will not occur under recommended storage conditions

Toxicological Information

Acute Toxicity: Oral LD₅₀ (rat): 740 mg/kg (literature variable); higher toxicity by inhalation and skin contact possible
Skin Corrosion/Irritation: Causes moderate to severe irritation
Eye Damage/Irritation: Causes irritation and potential damage
Respiratory Sensitization: May cause irritation of the airways, coughing, sore throat
Chronic Effects: Prolonged or repeated exposures can lead to liver and kidney impairment, similar to other chlorinated organics
Mutagenicity/Carcinogenicity: Not classified, limited data, handle with caution
Symptoms of Exposure: Drowsiness, dizziness, headaches, skin and eye burns

Ecological Information

Ecotoxicity: Harmful to aquatic life with long lasting effects (estimated due to structure similarity with related compounds)
Persistence and Degradability: Not easily biodegradable, may persist in environment
Bioaccumulative Potential: Moderate, log K_ow estimated at 2.7–3.4
Mobility in Soil: Low to moderate, likely binds with soil organic matter
Other Adverse Effects: Can impact microorganisms in soil and water; runoff can reach water sources
Avoid Release: Must not discharge into environment, hazardous for aquatic systems

Disposal Considerations

Waste Disposal Methods: Incinerate in approved chemical incinerator with afterburner and scrubber, dispose via licensed hazardous waste contractor in accordance with local, regional, and national laws
Packaging Disposal: Decontaminate empty containers, do not reuse, recycle if possible, destroy hazardous residue
Environmental Precautions During Disposal: Prevent leakages, avoid contamination of groundwater and waterways

Transport Information

UN Number: UN 1993
Proper Shipping Name: Flammable liquid, n.o.s. (contains 2-chloroethyl-benzene)
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: III
Marine Pollutant: Yes
Label Requirements: Flammable liquid symbol, environmental hazard where required
Special Precautions: Avoid transport with food and feed, ensure containers are upright and securely sealed

Regulatory Information

TSCA Status: Listed on TSCA Inventory
REACH Registration: Not registered, uses must be justified in compliance with local requirements
SARA Title III Section 313: Subject to reporting for certain usages
OSHA: Hazardous Chemical as defined by OSHA Hazard Communication Standard
WHMIS (Canada): Classified as hazardous
GHS: Meets requirements for flammable, irritant, environmental hazard
Other National Inventories: Confirm with local regulatory agencies
Labeling: Must meet national and international standards with clear warning and emergency details