Material Safety Data Sheet (MSDS): 2-Chloroethyl-Benzene

Identification

Product Name: 2-Chloroethyl-Benzene
Synonyms: 2-Phenylethyl chloride, β-Chloroethylbenzene
Chemical Formula: C8H9Cl
Molecular Weight: 140.61 g/mol
CAS Number: 100-44-7
Recommended Use: Intermediate in organic synthesis, solvent in laboratories, chemical manufacturing
Supplier Information: Manufacturer contact details should appear on the label or packaging
Emergency Number: Local emergency services or national poison center

Hazard Identification

Classification: Flammable liquid, irritant, possible carcinogen by various routes of exposure
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, may cause respiratory irritation, harmful if swallowed or inhaled, may cause cancer after long-term exposure, flammable liquid and vapor
Pictograms: Flame, exclamation mark, health hazard
Precautionary Statements: Avoid breathing vapors, use only outdoors or in well-ventilated area, keep away from open flames, sparks and direct heat sources, wash hands thoroughly after handling, wear protective gloves and eye protection
Potential Health Effects: Inhalation affects respiratory tract, skin contact leads to irritation, ingestion harms gastrointestinal tract, long-term exposure linked with potential organ damage

Composition / Information on Ingredients

Chemical Name: 2-Chloroethyl-Benzene
CAS Number: 100-44-7
Concentration: ≥ 98%
Impurities: Trace levels of benzene derivatives or unreacted starting materials
Additives: None typically added to technical grade material

First Aid Measures

Eye Contact: Rinse with plenty of water for at least 15 minutes, remove contact lenses if present and easy, seek medical attention for persistent irritation or pain
Skin Contact: Remove contaminated clothing, wash the affected area gently with soap and water, seek medical attention if irritation develops or persists
Inhalation: Move the person to fresh air immediately, keep at rest in a position comfortable for breathing, consult a physician if breathing difficulty continues
Ingestion: Rinse mouth with water, do not induce vomiting, seek immediate medical help, never give anything by mouth to an unconscious individual
Most Important Symptoms: Irritation, burning sensation in affected areas, coughing, difficulty breathing, nausea, dizziness

Fire-Fighting Measures

Suitable Extinguishing Media: Use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray
Unsuitable Extinguishing Media: Do not use a direct water jet which can spread flames
Specific Hazards: Vapors may form explosive mixtures with air, containers may explode when heated, combustion creates toxic gases such as hydrogen chloride, carbon monoxide, and carbon dioxide
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective clothing, avoid inhaling fumes
Special Procedures: Approach from upwind, evacuate area, keep run-off from entering drains or water sources

Accidental Release Measures

Personal Precautions: Wear appropriate respirator, chemical resistant gloves, goggles, and protective clothing
Environmental Precautions: Prevent further leakage or spillage, keep material out of sewers, surface water, and soil
Methods for Cleanup: Eliminate all sources of ignition, ventilate area, use inert absorbent (sand or vermiculite), collect spill in suitable non-sparking container, wash spill area with water and detergent
Disposal of Contaminated Material: Follow federal, state, and local environmental regulations

Handling and Storage

Handling: Use only in areas with proper ventilation, minimize contact with skin, eyes, and clothing, keep containers tightly closed, ground all transfer equipment, avoid the buildup of static electricity
Storage: Store in a tightly sealed container away from heat, sparks, open flames, oxidizing agents, acids, and bases, keep in a cool, dry, well-ventilated place
Incompatibilities: Strong oxidizing agents, acids, bases, peroxides
Safety Practices: Only trained personnel should handle, use explosion-proof equipment, keep emergency eyewash and showers accessible

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific occupational exposure limits set by OSHA or ACGIH; minimize exposure as much as possible
Engineering Controls: Install fume hoods or local exhaust systems for laboratory work, ensure good ventilation in all workspaces
Personal Protective Equipment (PPE): Gloves made of nitrile or neoprene, chemical safety goggles, flame-resistant lab coat, approved respirator for airborne concentrations above recommended levels
General Hygiene Measures: Wash hands before eating, drinking, or smoking after using this material, remove contaminated clothes and shower after work

Physical and Chemical Properties

Appearance: Colorless to pale yellow oily liquid
Odor: Aromatic, resembles benzene derivatives
Odor Threshold: Not readily available, likely low
pH: Neutral
Melting Point: -52°C
Boiling Point: 177-180°C
Flash Point: 54°C (closed cup)
Evaporation Rate: Not established
Flammability: Flammable liquid
Upper/Lower Flammability Limits: Data not fully established
Vapor Pressure: Approximately 0.5 mmHg at 25°C
Vapor Density: Heavier than air
Relative Density: 1.06 g/cm³ at 20°C
Solubility: Insoluble in water, mixes with organic solvents (ether, alcohol, chloroform)
Partition Coefficient (n-octanol/water): Estimated log Pow > 3
Auto-Ignition Temperature: Above 400°C
Decomposition Temperature: Not clearly determined
Viscosity: Not measured, typical of other similar aromatic solvents

Stability and Reactivity

Chemical Stability: Stable in original packaging under recommended storage conditions
Reactive Conditions: Exposure to heat, flame, and incompatible substances increases risk of decomposition
Incompatible Materials: Strong acids and bases, strong oxidizers, concentrated nitric acid, peroxides
Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, carbon dioxide, other hazardous gases
Polymerization Risk: Product does not polymerize under normal conditions

Toxicological Information

Possible Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: Harmful if swallowed; estimated oral LD50 for rats between 400–800 mg/kg; inhalation may irritate and damage respiratory tract
Skin Corrosion/Irritation: Expected to cause moderate irritation after prolonged exposure
Serious Eye Damage/Irritation: Causes burning, redness, and watering
Chronic Toxicity: Prolonged exposure may damage liver, kidneys, nervous system; possibly carcinogenic due to ethylene group
Sensitization: Not expected to cause allergies, but may irritate sensitive individuals
Mutagenicity & Carcinogenicity: Limited data, but structurally related chemicals have shown mutagenic and carcinogenic activity in rodents and humans
Specific Target Organ Toxicity: Prolonged or repeated exposures affect central nervous system and organs mentioned above

Ecological Information

Ecotoxicity: Toxic to aquatic life in high concentrations, fish and invertebrates vulnerable to spillage, causes short-term water contamination
Persistence and Degradability: Expected to degrade slowly in water and soil, risk of persistence with chronic releases
Bioaccumulation Potential: Potential to accumulate in aquatic organisms, high log Pow suggests increased risk
Mobility in Soil: Likely to move moderately due to low water solubility
Other Effects: Avoid release to environment, spills in waterways may pose threat to local wildlife

Disposal Considerations

Waste Generation: Collect as hazardous chemical waste at all times
Disposal Methods: Handle by incineration at a licensed facility, consult national, regional, and local waste regulations for approved disposal
Container Disposal: Empty containers should not be reused, triple rinse before discarding, dispose under hazardous waste guidelines
Precautions: Never pour down the drain, avoid release to environment

Transport Information

UN Number: UN 1993
UN Proper Shipping Name: Flammable liquid, n.o.s. (contains 2-Chloroethyl-Benzene)
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Environmental Hazards: Marine pollutant under IMDG code
Special Precautions for User: Ensure shipments comply with regulations, use proper labeling and packaging, segregate from incompatible substances, restrict movement with foodstuffs or feed

Regulatory Information

Safety, Health, and Environmental Regulations for Product: Subject to reporting under SARA Title III/EPCRA for certain thresholds, requires hazardous chemical inventory under OSHA Hazard Communication Standard, included in TSCA Inventory for the US, compliance with REACH obligations in the EU where applicable
Label Information: Product requires GHS-compliant labeling in workplaces
Further Legal Requirements: Follow all relevant environmental, health, safety, transportation, and waste disposal regulations in your jurisdiction, proper permits for storage and use, updated safety procedures for employees in regular contact