MSDS (Material Safety Data Sheet) – 2-Bromopropionyl Bromide

Identification

Product Name: 2-Bromopropionyl Bromide
Synonyms: Alpha-bromopropionyl bromide, 2-Bromopropanoyl bromide
Chemical Formula: C3H4Br2O
Molecular Weight: 215.87 g/mol
CAS Number: 585-70-8
Recommended Use: Chemical intermediate, organic synthesis
Manufacturer: [Company Information Supplied by Distributor]
Contact Information: [Supplier Contact Information Available on Label]
Emergency Telephone: [As Provided by Supplier]

Hazard Identification

GHS Classification: Acute Toxicity (Oral): Category 3; Skin Corrosion/Irritation: Category 1B; Serious Eye Damage: Category 1; Specific Target Organ Toxicity – Single Exposure: Category 3
Signal Word: Danger
Hazard Statements: Causes severe skin burns and serious eye damage; Toxic if swallowed or inhaled; May cause respiratory irritation
Pictograms: Corrosion, Skull and Crossbones, Exclamation Mark
Precautionary Statements: Avoid breathing vapors; Wear protective gloves, clothing, eye protection, and face protection; Wash thoroughly after handling; Do not eat, drink, or smoke during use

Composition / Information on Ingredients

Chemical Name: 2-Bromopropionyl Bromide
Concentration: 98–100%
CAS Number: 585-70-8
Impurities: Trace organic by-products below reporting threshold, non-hazardous

First Aid Measures

General Advice: Remove contaminated clothing, avoid contact with skin and eyes, seek immediate medical attention
Inhalation: Move person to fresh air, support breathing as needed, get emergency help
Skin Contact: Rinse skin gently with plenty of water for at least 15 minutes, remove contaminated clothing and shoes, consult medical services
Eye Contact: Flush eyes cautiously with water for several minutes, remove contact lenses if present and easy, get medical attention immediately
Ingestion: Rinse mouth cautiously, never give anything by mouth to an unconscious person, do not induce vomiting, get medical assistance

Fire-Fighting Measures

Suitable Extinguishing Media: Use dry chemical, carbon dioxide, or alcohol-resistant foam, water spray only for cooling containers
Specific Hazards Arising from the Chemical: Emits hydrogen bromide and carbon oxides on decomposition, corrosive and toxic vapors
Protective Equipment and Precautions: Firefighters wear self-contained breathing apparatus, fully protective suit resistant to chemicals, avoid exposure to combustion products
Special Procedures: Avoid runoff into drains, cool exposed containers with water spray from a safe distance

Accidental Release Measures

Personal Precautions: Evacuate area, ventilate, restrict access until cleanup complete, avoid inhalation/contact
Protective Equipment: Chemical-resistant gloves, appropriate goggles, full suit, NIOSH-approved respirator for vapor and gas
Environmental Precautions: Prevent from entering soil, sewers, surface water, notify authorities if contact with environment occurs
Cleanup Procedures: Absorb with inert material like dry sand or earth, do not use water directly, collect leaked material in secure, labeled container for disposal, ventilate area thoroughly

Handling and Storage

Safe Handling Practices: Work under well-ventilated conditions, avoid inhalation and direct contact, use fume hood, keep away from heat and incompatible materials
Hygiene Practices: Wash hands before breaks and at end of work, do not smoke, eat, or drink near chemical
Storage Requirements: Store in tightly closed original container, in cool, dry, well-ventilated area, protect from direct sunlight and moisture, segregate from acids, bases, oxidizers, and amines
Incompatible Materials: Strong oxidizing agents, reducing agents, water, alcohols, amines, metals

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific regulatory limits established for 2-Bromopropionyl Bromide but handle as highly hazardous
Engineering Controls: Use chemical fume hood, ensure eyewash stations and safety showers available
Personal Protective Equipment: Chemical splash goggles, face shield, acid/chemical resistant gloves (like nitrile or neoprene), lab coat or acid-resistant apron, rubber boots, NIOSH-approved respirator for vapors/mists
Environmental Controls: Use process enclosures, local exhaust ventilation, prevent spills or releases outside work area

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Pungent, irritating
Odor Threshold: Not established
pH: Not applicable
Melting Point/Freezing Point: -20°C (-4°F)
Boiling Point: 144°C (291°F) at 760 mmHg
Flash Point: Not available
Evaporation Rate: Not established
Flammability: Not classified as flammable
Vapor Pressure: 1 mmHg at 33°C
Vapor Density: Heavier than air
Relative Density: 2.103 g/cm³ at 20°C
Solubility: Reacts with water
Partition Coefficient (n-octanol/water): Not determined
Auto-ignition Temperature: Not applicable
Decomposition Temperature: Not determined
Viscosity: Not determined

Stability and Reactivity

Chemical Stability: Stable under specified storage conditions, sensitive to moisture
Hazardous Reactions: Reacts violently with water, alcohols, and amines, generates toxic gases
Conditions to Avoid: Heat, flame, humidity, incompatible materials, sources of ignition
Incompatible Materials: Water, alcohols, strong bases, acids, amines, oxidizing and reducing agents
Decomposition Products: Hydrogen bromide, carbon monoxide, carbon dioxide, toxic fumes formed on combustion or decomposition

Toxicological Information

Acute Toxicity: Highly toxic by inhalation, ingestion, and skin absorption
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Symptoms of Exposure: Severe respiratory tract irritation, coughing, difficulty breathing, burns to skin and eyes, abdominal pain, vomiting, and potentially fatal pulmonary edema
Chronic Effects: Prolonged or repeated exposure may cause dermatitis, chemical burns, prolonged respiratory irritation
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Mutagenicity: Data lacking
Reproductive Toxicity: Data lacking

Ecological Information

Aquatic Toxicity: Very toxic to aquatic organisms based on structural class similar chemicals
Mobility: Reacts with water, binds with soil
Degradability: Rapid hydrolysis in water, forms bromide ions and organic acids
Bioaccumulation: Not expected as main degradation products are highly soluble in water, but local toxicity is still significant
Other Adverse Effects: Can acidify water bodies, disrupt aquatic life

Disposal Considerations

Waste Disposal: Dispose of as hazardous waste per local and national regulations, incineration under controlled conditions preferred, avoid direct discharge to environment
Contaminated Packaging: Rinse containers with appropriate neutralizing solution under fume hood, dispose of according to hazardous chemical waste guidelines
Precautions: Do not reuse empty containers, label and transport for proper chemical disposal

Transport Information

UN Number: UN 3265
Proper Shipping Name: Corrosive liquid, acidic, organic, n.o.s. (contains 2-Bromopropionyl bromide)
Transport Hazard Class: 8 (Corrosive substances)
Packing Group: II
Labels: Corrosive
Special Provisions: Keep away from foodstuffs, perishable goods, incompatible materials; use leak-proof, corrosion-resistant containers
Marine Pollutant: Yes

Regulatory Information

OSHA Status: Considered highly hazardous according to OSHA’s hazardous chemicals rule
EPA TSCA Inventory: Listed
SARA Title III: Not specified as an extremely hazardous substance, but subject to reporting for releases
CERCLA Reportable Quantity: Not assigned, but spills should be reported according to local regulatory guidance
REACH: Subject to registration, usage and restrictions in the EU
Other: Use of personal protective equipment and adherence to organizational safety protocols required by most jurisdictions
Local Regulations: Additional rules may apply under state, provincial, or national legislation