2-Bromopropionyl Bromide: Insight and Impact in Modern Chemistry
Historical Development
Chemistry often builds on incremental advances from labs in universities and industries alike. 2-Bromopropionyl bromide traces its roots back to the surge in organohalide research during the mid-20th century. As chemists sought effective methods for acylation and bromination, this acyl bromide cropped up in patents and journals throughout the 1950s and 1960s. Organic synthesis demanded ever more reactive intermediates, and researchers discovered that brominated acyl halides offered superior selectivity and mild conditions compared to earlier chlorinated analogues. Makers of specialty chemicals and pharmaceutical ingredients steadily adopted 2-bromopropionyl bromide, driven by a need for reliable, predictable performance in multi-step syntheses. This history shapes the robust role the compound plays in current processes.
Product Overview
2-Bromopropionyl bromide sits squarely among the trusted cornerstones of acylation chemistry. Chemists appreciate its dual bromine atoms: one attached to the acyl group and one as the alpha-branched halide. This gives the molecule both reactivity and tailored selectivity in complex syntheses. Manufactured at scales ranging from multi-gram batches for R&D to drum quantities for industry, this compound offers pragmatic versatility in research and manufacturing pipelines. The product commonly shows up in synthesis of pharmaceuticals, agrochemicals, specialty polymers, and as a key intermediate in many complex molecular arrangements.
Physical and Chemical Properties
Experience in the lab highlights certain quirks about the physical nature of 2-bromopropionyl bromide. The liquid usually presents as a colorless to pale yellow, strongly fuming in open air due to its reactivity with moisture. The pungent, acrid odor makes handling impossible without proper fume extraction. Boiling point hovers around 149-151°C under atmospheric pressure. The density sits near 1.9 g/cm³—significantly heavier than water—owing to the two bromine atoms packed into a small carbon backbone. Solubility remains limited in water due to immediate hydrolysis, but organic solvents such as dichloromethane or toluene easily dissolve it. From a chemical standpoint, the molecule reacts aggressively with nucleophiles: water, alcohols, and amines trigger rapid acylation or bromide substitution, often yielding corrosive byproducts like hydrogen bromide.
Technical Specifications and Labeling
Chemical supply houses typically use rigorous quality checks prior to packaging. High-purity material demands precise distillation or recrystallization. Typical labeling reflects purity in the range of 95-99% by GC or NMR. The container materials matter as 2-bromopropionyl bromide can attack plastics not formulated for halide resistance, so glass or certain fluoropolymers are preferred. Safety labeling carries hazard designations for corrosivity, acute toxicity, and environmental risk, consistent with GHS and REACH standards. Transport regulations—such as UN number 3265—apply due to the compound’s potential for serious harm upon leakage or improper storage.
Preparation Method
In practical settings, chemists typically make 2-bromopropionyl bromide from 2-bromopropionic acid. The acid gets treated with phosphorus tribromide or thionyl bromide, usually under controlled conditions to prevent side reactions or over-bromination. This transformation converts the carboxylic acid group into the more reactive acyl bromide, with simultaneous evolution of gaseous byproducts that need careful scrubbing. The lab or production setup often involves inert gas sweep, low temperature, and staged addition to contain heat and fume release. Purification typically involves distillation under reduced pressure, yielding a clear, potent liquid ready for further transformations.
Chemical Reactions & Modifications
The power of 2-bromopropionyl bromide comes through in its acylation chemistry. It reacts rapidly with amines to create amides, with alcohols to create esters, and engages in alpha-bromination strategies in the assembly of heterocyclic rings. The compound’s reactivity makes it valuable in peptide synthesis, where the introduction of an acyl group and an alpha-bromine moiety can build in molecular handles for later transformations or improve pharmacological profiles. In organic electronics, researchers build custom polymers using acyl bromides for coupling reactions. As an electrophile, 2-bromopropionyl bromide can participate in Friedel–Crafts acylation when coupled with strong Lewis acids, constructing frameworks in aromatic chemistry that would be difficult or inefficient with milder reagents.
Synonyms & Product Names
Different sources may catalog 2-bromopropionyl bromide under various names. Commonly, chemical suppliers refer to it as α-bromopropionyl bromide or 2-bromo-1-bromopropan-1-one. CAS registry number 585-71-7 consistently provides traceability for scientists and procurement departments alike. Additionally, trade catalogs in some regions might simply title it “Bromopropionyl Bromide” or use abbreviations like 2-BPB for process documentation.
Safety & Operational Standards
Personal protective equipment forms the frontline defense in handling. Face shields, durable gloves made of neoprene or nitrile, and splash-proof lab coats are non-negotiable. Operators learn quickly from experience—skin contact or inhalation leads to immediate pain, irritation, and lasting injury. In enclosed processing, fume hoods or gloveboxes are standard. Storage demands sealed containers in cool, ventilated areas with rigorous access control. Leak detection and emergency neutralization stations, using soda or sodium thiosulfate solutions, are permanently staged in work areas. Regulatory agencies pay close attention: documentation of training, risk assessment, and emergency procedures undergo frequent audits, particularly where scale-up or manufacturing occurs.
Application Area
Pharmaceutical chemists value 2-bromopropionyl bromide for its use in fine-tuning drug molecules. It plays a big part in introducing bromo-functionalized side chains, often as key intermediates in pain medications, antimicrobials, and central nervous system drugs. Agrochemical researchers apply its acylating power to prepare herbicide and fungicide precursors. The electronics field explores its use in modifications of complex polymers, chasing after new conductivity or structural features for next-generation display materials. Academic labs world over continue to adapt this building block for the total synthesis of natural products, or as a tool to attach radiolabels in advanced imaging probes. This constant push for new functionality keeps 2-bromopropionyl bromide relevant in the toolbox of builders working at the atomic level.
Research & Development
Forward-thinking R&D teams often rely on 2-bromopropionyl bromide when seeking new reactions that break old bottlenecks. In recent years, efforts have targeted greener processes that reduce byproduct formation—employing novel reagents or catalysts to tame the reactivity without sacrificing yield. Epigenetic drug research, for example, tests analogues that modify small molecule interactions at key molecular sites, using the flexibility of acyl bromides to swap components with precision. Process scale-up groups look for ways to recycle byproducts or avoid costly neutralization steps, tracking environmental impact as closely as speed or efficiency. This spirit of measured innovation keeps the compound visible both in the literature and in filed patents, as new application areas demand tailored chemical transformations that older reagents can’t match.
Toxicity Research
Lab exposure data and animal studies highlight the serious hazards associated with 2-bromopropionyl bromide. Acute toxicity stems from rapid hydrolysis on contact with moist skin, producing both the parent acid and hydrobromic acid. These cause pain, blistering, and deep tissue damage. Inhalation of fumes irritates the respiratory tract, with documented cases leading to bronchospasm and pulmonary edema in insufficiently ventilated spaces. Chronic animal studies suggest possible organ targeting—especially to respiratory tissues—though long-term human data remains sparse due to strict regulatory handling requirements. Regulators urge a precautionary approach for environmental release, as bromo-organic compounds can linger in waterways and soil, impacting aquatic ecosystems. Risk management depends on well-maintained containment and immediate first-response procedures for any exposure.
Future Prospects
The search for safer, more efficient chemical building blocks keeps 2-bromopropionyl bromide in sight for formulators and innovators. Trends toward greener chemistry may drive development of less hazardous analogues, but the unique reactivity of acyl bromides ensures a continuing niche in precision synthesis. Technologies like flow chemistry may further reduce risks by minimizing the quantity handled at any given time, and digital automation opens lines for remote and high-throughput experimentation. The ongoing call for custom-tailored molecules in medicine, agriculture, and materials science means approaches using this compound remain a mainstay, even as environmental and workplace safety regulations push suppliers and users to improve stewardship and transparency.
Behind the Formula: C3H4Br2O
Stepping into any chemistry lab, you see shelves full of bottles labeled with cryptic formulas. One jar catches the eye: 2-Bromopropionyl bromide, with the formula C3H4Br2O. What seems like a jumble of atoms spells out a lot about how labs, industry, and even science education work day to day.
Why Getting the Formula Right Matters
It’s easy to overlook details in a chemical name, but experience has taught me a missed atom or a switched functional group brings problems fast. C3H4Br2O means three carbons, four hydrogens, two bromine atoms, and an oxygen. That exact ratio affects everything—reactivity, storage, and safety handling procedures.
A friend once shared a story from an organic chemistry class: a mix-up between 2-bromopropionyl bromide and a similar-sounding compound led to a failed reaction and a stinky lab. Turns out, even one extra or missing bromine flipped the outcome. That scene plays out daily across thousands of hospitals and warehouses. Precision isn’t some abstract ideal—it keeps experiments, medicines, and products on track.
Chemistry in the Real World: Consequences and Responsibility
The classroom drills formulas for good reason. Take 2-bromopropionyl bromide as the example. It’s a building block in organic chemistry, and people use it to make custom molecules, pharmaceuticals, and agrochemicals. The two bromines in the formula make it reactive for introducing bromine into other molecules—a crucial step for specialized drugs or materials. If the label reads wrong, people risk production errors, wasted money, or even injuries.
Labs and industry rely on clear standards. The formula C3H4Br2O tells teams how much compound to weigh, how to prepare reaction vessels, and which protective gear to choose. On top of that, safety sheets reference these formulas when noting hazards, so everyone in the lab understands the risks. Breathing in vapors or spilling a drop brings dangers that accurate labeling and formula knowledge help reduce.
Bridging Science and Society Through Clear Information
In real life, knowledge gaps about chemicals cause more than minor confusion. A wrong formula on a bottle often sparks chain reactions: supply chain slowdowns, regulatory violations, or even public scares if a chemical leaks. Fact checks, peer-reviewed references, and consistent double-checks help bridge that gap. For example, Material Safety Data Sheets (MSDS) and digital lab inventories have made cross-referencing much easier. That’s how the industry chips away at errors, improves transparency, and keeps the workforce safe.
People in chemistry—students, researchers, or technicians—know that formulas aren’t just textbook trivia. Each one, like C3H4Br2O, comes with a weight of responsibility. Safe storage and transport require a full understanding of what’s in each bottle. Mistakes mean real impacts on timelines, budgets, and health.
Tackling Formula Mistakes: Practical Steps
To prevent formula-related setbacks, teams check batch numbers, review supplier paperwork, and standardize electronic records. Even changing how bottles are labeled—adding scannable QR codes linked to formulas and safety data—has reduced mix-ups in labs I’ve seen. Building these habits into team culture pays off with fewer errors, safer workspaces, and stronger trust down the line.
So, the next time someone asks about the chemical formula of 2-bromopropionyl bromide, the answer—C3H4Br2O—carries more significance than a string of characters. It’s a signal for accuracy, attention, and protecting both people and progress.
Bridging Research and Industry
2-Bromopropionyl bromide doesn't show up in the news like new medicines or electric cars, but folks who spend their lives in laboratories know its value. As someone who has spent time working next to chemists day in and day out, I’ve seen first-hand how important raw chemical building blocks can be. This compound is more than just a mouthful of a name; it quietly supports research in a variety of fields, from drug development to advanced materials.
Driving Pharmaceutical Synthesis
Drug discovery isn’t about luck; it requires reliable reactions and predictable steps. 2-Bromopropionyl bromide offers a brominated acyl group, letting chemists introduce specific structures to drug candidates. Take the work on β-amino acid derivatives, which play a big role in new antibiotics and anti-inflammatory molecules. The compound allows precise addition of functional groups, and its strong reactivity speeds up stages that might otherwise drag on. Medicinal chemists often share stories about how certain steps get jammed up by less effective reagents, but this one stands out for cutting down failure rates in key reactions.
Chemical Intermediates at the Core
Intermediates create the links in the chain for specialty chemicals, and this is where 2-Bromopropionyl bromide shows its muscle. For example, in the field of agrochemicals, a bromine atom in the right spot can deliver potent weed and pest control. Adding propionyl bromides to a chemical toolbox allows for the production of molecules that resist breakdown in field conditions. Chemists in crop science point to better yields and longer shelf lives because of these precise modifications, ultimately helping farmers maintain healthy crops without needing harsher treatments.
Protein Modification and Biomolecule Tools
Modern biotechnology depends on clever chemical reactions. Scientists performing protein modification in the lab rely on compounds that can target specific amino acids. 2-Bromopropionyl bromide reacts readily with thiols and amines, so researchers use it to alter cysteine or lysine residues on enzymes or antibodies. With these modifications, labs turn “dull” proteins into diagnostic agents or molecular probes, fueling breakthroughs in disease detection and mapping out metabolic pathways. My own experience working with protein labeling showed just how tricky it can be to get targeted results, but using reliable reagents like this one cuts down on frustration and wasted material.
Handling and Safety Matter
This chemical doesn’t just walk into a lab without protocol. It carries risks—exposure can burn the skin, eyes, or lungs, and it releases corrosive gases. Every researcher I’ve known uses fume hoods and keeps neutralizing agents nearby. Chemical safety is no joke; too many accidents start with ignoring the warnings on bottles like this. The best labs create checklists and train new staff with hands-on routines, not just safety lectures. Labs working with these reagents often rely on digital records to track usage and monitor incidents, helping avoid repeat problems.
Supporting Responsible Use Through Better Information
The story behind this compound is really a story about responsible innovation. With clear labeling, up-to-date data sheets, and strong internal safety cultures, research organizations turn potential hazards into stepping stones for new discoveries. Collaboration between chemical suppliers, academic labs, and industry partners matters just as much as the molecules being moved around. Open sharing of safety protocols and troubleshooting tips helps the scientific community build trust and stay ahead of changing regulations. Transparency and responsibility make a difference not only in research success but in protecting people and the environment.
Understanding What We’re Dealing With
2-Bromopropionyl bromide shows up in labs as a sharp, strong-smelling liquid. Anyone who’s spent time working with acyl halides knows the sting these chemicals can bring—not just to skin, but also to the respiratory tract. This chemical reacts with water fast, giving off hydrogen bromide gas and making a pretty caustic mess. You don’t want to discover a leak just by following the smell, that’s for sure.
Storing 2-Bromopropionyl Bromide: Getting Specific
A dry, cool place ranks as the best spot for 2-Bromopropionyl bromide. Moisture is trouble here. Every drop of humidity that sneaks into a container can trigger hydrolysis. That means pressure in the bottle, corrosion around the lids, and possible gas leaks. Even small spills can lead to a lab clearing out in a hurry. From experience, folks underestimate how fast things get out of hand with these reactive chemicals.
The right container helps prevent exposure. Glass bottles work, but only with tight PTFE-lined screw caps—not old rubber stoppers or worn plastic lids. Over time, bromide fumes chew up weaker seals, letting in air and letting out fumes. Having handled compromised acid halide bottles before, I’ve seen glass threads clogged with crusty byproducts. That gunk signals your protection has failed, and every breath becomes a gamble.
Temperature: Calm and Consistent
Room temperature can work for some chemicals, but not this one. For long-term storage, a refrigerator dedicated to chemicals—not food—keeps 2-Bromopropionyl bromide at less than 8 °C. Fluctuations encourage decomposition, especially during hot summers or in rooms with poor climate control. People sometimes tuck reactive reagents in back offices or closets for quick access. Over time, those warmer temperatures cook up gas and pressure until a cap pops loose or a jar cracks.
Putting bromides alongside acids or bases causes headaches. Cross-contamination has led to all sorts of emergencies—color changes, hissing bottles, strange odors that force evacuations. Separate shelves for acid halides sit at the top of chemical safety lists for good reason. Metal shelving runs the risk of corrosion if a leak happens, so I always look for sealed plastic or epoxy-lined shelves in chemical storerooms.
Ventilation: It’s Non-Negotiable
A chemical like this calls for a proper ventilated cabinet. Not a kitchen cupboard. Not a drawer. Fume hoods and vented storage both help limit accidental exposure. If a bottle gets knocked over, the fumes should leave the room before anyone breathes them in. Labs using ductless chemical storage units often fit carbon or acid gas filters. Without those, the risk to everyone’s lungs increases.
Preparation for Emergencies
Before storing any strong acyl bromide, make sure spill kits mean more than paper towels and gloves. You’ll want extra absorbent material, full-face respirators, and containers for neutralizing spills. Teams that run monthly drills respond quicker, and their safety record proves it.
Bottom Line: Why Care?
2-Bromopropionyl bromide doesn’t forgive carelessness. Good storage habits do more than keep inventory tidy; they prevent injuries and save money. Long ago, poor storage left us scrambling after a simple jar break. Since then, nothing beats dry shelves, cold rooms, tight seals, and solid protocols. Anyone using or storing this chemical should always treat it with healthy respect and strong procedures.
Respect the Risks: What’s in the Bottle?
2-Bromopropionyl bromide isn’t some mild, everyday chemical. This stuff acts as a strong acylating agent. Crack open the bottle, even for a second, and you’ll hear stories from folks in the lab who’ve learned the hard way: this chemical bites back. The vapor makes your throat scratchy, your eyes water, and if a drop touches your skin, you’ll feel the burn soon enough. The science says it’s nasty on contact and hazardous if inhaled. In the world of hazardous chemicals, you treat this with the same care you give strong acids or lachrymators like thionyl chloride.
Personal Protective Equipment Is Not Up for Debate
Nobody argues about wearing personal protective equipment around 2-bromopropionyl bromide. Standard gear means a properly fitted lab coat, goggles that seal around your eyes, and gloves – not those cheap vinyl ones, but real chemical-resistant gloves. Don’t trust your hands to luck or latex. Splash protection means tying your hair back, rolling down those sleeves, and sometimes pulling on a face shield if you’re pouring or transferring the stuff. If you’ve ever watched a seasoned chemist work, there’s little room for shortcuts. They respect the stuff because stories spread fast: lingering hand burns, ruined glasses, coughing fits that last a week.
Ventilation Counts for Everything
Every chemist has heard the tale of someone opening a bottle outside the fume hood. Once those fumes hit the air, you know it right away, everyone does. These vapors are heavy, and they stay low, potentially causing trouble for anyone in the room. Fume hoods save lives, plain and simple. Those fans? They aren’t just for show. If you don’t feel the airflow at the sash, fix it before breaking open a container. Don’t even set up the glassware on the bench top. If you’re not sure about the hood, ask someone who knows how to check it. I remember an old grad student who did — cut short a reaction when the airflow monitor blinked red, then called in maintenance.
Storage: Out of Sight, Secure, and Upright
No one wants a leaky bottle rolling around in a drawer. Store 2-bromopropionyl bromide in a well-ventilated chemical cabinet, away from moisture and incompatible chemicals like strong bases or oxidizers. These bromine-containing reagents don’t play well with others — even a drop of water or a splash from a cleaning rag can lead to a mess fit for the fire department. On top of that, keep the container tightly closed, label it clearly, and never, ever use an unlabeled bottle you find in a random fridge or cabinet. If you find a sticky cap, clean it up and tell the safety officer. I’ve seen too many accidents start with sticky bottles and crumbling labels.
Spill Response: Plan Before Trouble Hits
No lab wants to scramble if something spills. The right move means everyone on the team thinks out loud before starting any work. Spill kits should sit near the workspace, well-stocked with neutralizing agents, gloves, and absorbent materials. Keep emergency eyewash and showers accessible and know the quickest path. If you do spill, don’t be a hero: alert your lab mates, use the kit, and let your safety officer step in. After all these years in the lab, I’ve seen rushed, panicked reactions turn close calls into serious incidents.
Health First, Productivity Second
Every workplace pushes for speed, but it never pays to gamble with chemicals like 2-bromopropionyl bromide. A little planning, suited-up protection, and some honest patience can save not just your project, but also your health. The facts show it: cutting corners leads to pain, lost time, and regret. Take it from personal experience — you go home feeling better at the end of the day if you put safety first.
The Significance of CAS Numbers in Chemistry
Every chemical compound needs a way to stand out from the crowd. On lab shelves around the world, two bottles might look nearly identical, but the compound inside can be vastly different. Without a precise system, mistakes could mean wasted research or worse, real safety risks. This is where the Chemical Abstracts Service (CAS) number comes into play, and for 2-Bromopropionyl bromide, that identifier is 2114-00-3. Think of a CAS number as a chemical’s fingerprint—a way for scientists, suppliers, and regulators to know exactly what they’re working with, no matter what language they speak or what naming convention they follow.
Why 2-Bromopropionyl Bromide Deserves Attention
Many people never hear about 2-Bromopropionyl bromide outside academic or industrial labs, but it fills important roles in those environments. Its CAS number helps researchers trace its use and comply with regulations. This compound shows up as a building block for pharmaceuticals, agrochemicals, and specialty materials. In my experience around industrial chemists, knowing the exact structure and properties means being able to handle potential hazards, toxicity, and reactivity without guesswork.
Risks and Responsible Handling
A name like 2-Bromopropionyl bromide, paired with its CAS number, quickly flags the need for safe handling. Chemicals with reactive bromine atoms often bring extra hazards. They can cause burns, release toxic vapors, and demand proper storage away from moisture. I’ve seen minor errors in identification lead to mixed containers and almost turn into accidents. Laboratories rely on the CAS number system during audits and training sessions to fix these problems before they start. Lab techs scan a label, spot the 2114-00-3 ID, and instantly know to reach for gloves, goggles, and a fume hood.
Keeping Science Transparent for Everyone
Open information makes the whole system safer. Regulations count on each CAS number to make shipping and storage rules clear. Mistakes in labeling or confusing similar-sounding names can stop a shipment at customs or get a research project shut down by safety inspectors. The CAS registry—run by the American Chemical Society—ensures each chemical tracked has a unique number. This record helps regulators screen ingredients, universities share research, and families understand product safety sheets at home.
Moving Toward Better Safety
Science and industry care more about transparency than ever before. As new chemicals like 2-Bromopropionyl bromide reach the market, oversight groups lean on the CAS system not just for managing risk, but also for promoting collaboration. Online databases open access for academics, environmental groups, and first responders. Public health relies on being able to trace an incident back to the right chemical. That way, medical workers and poison control hotlines offer clear, fast instructions in an emergency.
Finding Solutions Together
Teaching students and young techs to read CAS numbers forms the backbone of chemical education. In my years spent mentoring interns, I’ve seen hands-on training lead to better decisions and safer labs. Building a stronger relationship between academia, government, and the private sector helps everyone work from the same playbook. Quick access to CAS numbers like 2114-00-3 boosts both safety and innovation, letting researchers test more ideas and share their findings without confusion.
| Names | |
| Preferred IUPAC name | 2-bromopropanoyl bromide |
| Other names |
2-Bromopropanoyl bromide
2-Bromopropionic acid bromide alpha-Bromopropionyl bromide Bromo(propionyl)bromide |
| Pronunciation | /tuː-broʊmə-ˈproʊpiəˌnɪl ˈbroʊmaɪd/ |
| Identifiers | |
| CAS Number | 2114-00-3 |
| 3D model (JSmol) | `3D model (JSmol): BrC(C(=O)Br)C` |
| Beilstein Reference | 1209243 |
| ChEBI | CHEBI:85072 |
| ChEMBL | CHEMBL373685 |
| ChemSpider | 20518 |
| DrugBank | DB04114 |
| ECHA InfoCard | 03f03c42-623e-4e9a-a388-7d425bbd2199 |
| EC Number | 211-673-8 |
| Gmelin Reference | Gm. 8338 |
| KEGG | C19133 |
| MeSH | D017962 |
| PubChem CID | 11643 |
| RTECS number | UF8225000 |
| UNII | ZE5577DXD5 |
| UN number | UN2346 |
| CompTox Dashboard (EPA) | DTXSID7020823 |
| Properties | |
| Chemical formula | C3H4Br2O |
| Molar mass | 215.83 g/mol |
| Appearance | Colorless to yellow liquid |
| Odor | Pungent |
| Density | 1.97 g/mL at 25 °C (lit.) |
| Solubility in water | Reacts with water |
| log P | 0.5 |
| Vapor pressure | 5 mmHg (20°C) |
| Acidity (pKa) | -7.1 |
| Basicity (pKb) | pKb = -7.7 |
| Magnetic susceptibility (χ) | -7.03 × 10⁻⁶ cm³/mol |
| Refractive index (nD) | 1.493 |
| Viscosity | 1.792 cP (20°C) |
| Dipole moment | 2.60 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 367.7 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | -247.7 kJ/mol |
| Std enthalpy of combustion (ΔcH⦵298) | -436.3 kJ/mol |
| Hazards | |
| Main hazards | Corrosive, causes burns, toxic if inhaled, harmful if swallowed, reacts violently with water. |
| GHS labelling | GHS02, GHS05, GHS06 |
| Pictograms | GHS06, GHS05 |
| Signal word | Danger |
| Hazard statements | H302, H314, H331, H335 |
| Precautionary statements | P210, P220, P260, P264, P271, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P370+P378, P405, P501 |
| NFPA 704 (fire diamond) | 3-3-0-W |
| Flash point | 82°C |
| Lethal dose or concentration | LD50 oral rat 430 mg/kg |
| LD50 (median dose) | LD50 (median dose): 430 mg/kg (rat, oral) |
| NIOSH | BR8100000 |
| PEL (Permissible) | Not established |
| REL (Recommended) | 0.1 ppm |
| IDLH (Immediate danger) | Unknown |
| Related compounds | |
| Related compounds |
Propionyl bromide
2-Bromopropionic acid Acetyl bromide |
