Material Safety Data Sheet (MSDS) for 2-Bromopropionic Acid

Identification

Chemical Name: 2-Bromopropionic acid
Synonyms: Propanoic acid, 2-bromo-; α-Bromopropionic acid
Product Number: Catalog-specific
Recommended Use: Chemical synthesis, laboratory reagent
Manufacturer Information: Supplier address, city, contact phone, emergency contact
Molecular Formula: C3H5BrO2
Molecular Weight: 152.98 g/mol
CAS Number: 598-72-1

Hazard Identification

GHS Classification: Acute toxicity (oral, dermal), skin corrosion/irritation, serious eye damage/irritation
Hazard Statements: Harmful if swallowed or in contact with skin. Causes skin burns and eye damage.
Pictograms: GHS05 (Corrosive), GHS07 (Exclamation mark)
Signal Word: Danger
Precautionary Statements: Wear protective gloves and eye protection. Avoid breathing dust or vapors. Wash hands thoroughly after handling.
Potential Health Effects: Direct skin or eye contact leads to burns, severe irritation, redness. Ingestion can cause nausea, abdominal pain.

Composition / Information on Ingredients

Chemical Name: 2-Bromopropionic acid
Concentration: 98–100%
CAS Number: 598-72-1
Other Ingredients: None identified

First Aid Measures

Eye Contact: Rinse carefully with running water for at least 15 minutes. Remove contact lenses if easy. Seek medical attention.
Skin Contact: Rinse skin with water or shower. Remove contaminated clothing. Get medical help.
Inhalation: Move person to fresh air. Keep at rest in a position comfortable for breathing. Call a physician if symptoms do not subside.
Ingestion: Rinse mouth. Do not induce vomiting. Never give anything by mouth to an unconscious person. Seek medical care immediately.
Most Important Symptoms: Chemical burns, respiratory irritation, persistent pain or vision changes.

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, alcohol-resistant foam, carbon dioxide, dry chemical
Specific Hazards: Toxic and irritating gases like hydrogen bromide, carbon oxides
Protective Equipment: Use self-contained breathing apparatus and protective clothing
Firefighting Instructions: Stay upwind. Cool containers exposed to fire with water spray. Evacuate area if large fire.

Accidental Release Measures

Personal Precautions: Use chemical-resistant gloves, eye protection, lab coat. Ensure adequate ventilation. Do not breathe vapors.
Environmental Precautions: Prevent from entering drains or water sources.
Cleanup Methods: Soak up with inert absorbent like sand. Place in chemical waste container. Wash area with plenty of water.

Handling and Storage

Safe Handling: Use only in fume hood or well-ventilated space. Avoid direct contact or inhalation. Handle away from sources of ignition or heat.
Storage Conditions: Store tightly closed in cool, dry, well-ventilated area away from incompatible materials. Use corrosion-resistant containers.
Incompatibilities: Bases, strong oxidizing agents, reducing agents, metals

Exposure Controls and Personal Protection

Engineering Controls: Use chemical fume hood, safety showers, eyewash fountains.
Exposure Limits: No established workplace exposure limits for this material
Personal Protection: Chemical-resistant gloves (nitrile or neoprene), safety goggles or face shield, protective clothing such as lab coat
Respiratory Protection: Respirator with organic vapor/acid gas cartridge if ventilation inadequate
Hygiene Measures: Wash hands before breaks and at end of work. Remove contaminated clothes.

Physical and Chemical Properties

Appearance: Clear to pale yellow liquid or crystals
Odor: Pungent, strong
pH: Acidic, less than 2 (aqueous solution)
Melting Point: 48–51°C
Boiling Point: 189°C
Flash Point: Not determined
Solubility: Miscible with water
Density: 1.68 g/cm³
Vapor Pressure: Not available
Partition Coefficient: Not available

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions.
Conditions to Avoid: Heat, flames, moisture, incompatible chemicals
Hazardous Decomposition Products: Hydrogen bromide, carbon oxides, irritating fumes
Reactivity: Reacts with bases and strong oxidizers.

Toxicological Information

Acute Toxicity (oral, rat): LD50 >200 mg/kg
Routes of Exposure: Skin contact, inhalation, ingestion, eye contact
Symptoms: Burns, severe irritation, abdominal pain, cough, shortness of breath
Chronic Toxicity: Prolonged exposure may cause organ damage, sensitization, or allergic reaction
Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic by regulatory agencies
Additional Effects: May aggravate pre-existing skin, eye, or respiratory conditions

Ecological Information

Toxicity to Aquatic Life: May cause harmful effects to aquatic organisms
Persistence and Degradability: Data not fully available; presumed to degrade slowly in the environment
Bioaccumulation Potential: Low potential based on structure
Mobility in Soil: Likely to leach into soil and groundwater if spilled
Other Adverse Effects: Avoid release to environment; not classified as persistent organic pollutant

Disposal Considerations

Product Disposal: Dispose of in accordance with local, national, and international regulations. Consult licensed waste disposal company.
Contaminated Packaging: Clean containers thoroughly before recycling or disposal; treat as hazardous waste
Special Precautions: Avoid release into sewage, surface waters, or soil.

Transport Information

UN Number: 3265
UN Proper Shipping Name: Corrosive liquid, acidic, organic, n.o.s. (2-Bromopropionic acid)
Transport Hazard Class: 8 (Corrosive Substances)
Packing Group: II
Transport Labels Required: Corrosive (Class 8 label)
Environmental Hazards: Avoid spills into waterways

Regulatory Information

OSHA: Corrosive, regulated as hazardous chemical
EPA: May be regulated as hazardous waste
TSCA: Listed in inventory
REACH: Registered as substance of very high concern
SARA Title III: Not listed for Section 302 or 313
California Proposition 65: Not listed
Other Regulatory Info: Handle according to relevant local, regional, and national laws. Consult safety authorities for updates.