Material Safety Data Sheet – 2-Bromo-2-Methylpropionic Acid

Identification

Product Name: 2-Bromo-2-Methylpropionic Acid
Chemical Formula: C4H7BrO2
CAS Number: 598-31-2
Synonyms: α-Bromo-α-methylpropionic acid; 2-Bromo-2-methylpropanoic acid
Recommended Use: Laboratory chemicals, research and development
Supplier Information: Seek the supplier or distributor name and contact, usually found on the packaging label or sourcing documentation
Emergency Telephone: Refer to local regulations or supplier's emergency contact number

Hazard Identification

Classification: Corrosive, Causes skin burns and eye damage, Harmful if inhaled or ingested
GHS Label Elements: Danger
Hazard Statements: H314: Causes severe skin burns and eye damage; H302: Harmful if swallowed
Precautionary Statements: Wash thoroughly after handling; Wear protective gloves, clothing, and eye protection; Do not breathe dust or vapor; If inhaled, remove to fresh air
Signal Word: Danger
Pictograms: Corrosive, Exclamation mark
Routes of Exposure: Skin, eye, inhalation, ingestion
Effects of Overexposure: Severe irritation or burns to skin, eyes, respiratory tract, and digestive tract

Composition / Information on Ingredients

Chemical Identity: 2-Bromo-2-Methylpropionic Acid
Concentration: Typically pure, up to 100%
Impurities: Variable depending on manufacturer; minor organic contaminants possible
EC Number: 209-939-2
Molecular Weight: 167.00 g/mol

First Aid Measures

Eye Contact: Rinse immediately with plenty of water for at least 15 minutes, keeping eyelids open; Seek medical attention without delay
Skin Contact: Remove contaminated clothing; Rinse skin with water and soap for at least 15 minutes; Get medical help
Inhalation: Move person to fresh air; If breathing becomes difficult, give oxygen; Contact medical services
Ingestion: Rinse mouth with water, never give anything by mouth to an unconscious person; Do not induce vomiting; Call poison control or a doctor
Most Important Symptoms: Burning pain, redness, ulceration, severe eye injury risk
Immediate Medical Attention: Needed for significant exposure via any route

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: Direct water jet may spread product
Specific Hazards: Releases toxic and corrosive fumes of hydrogen bromide, carbon monoxide, and carbon dioxide under fire conditions
Protective Equipment for Firefighters: Full protective clothing, self-contained breathing apparatus
Firefighting Instructions: Keep containers cool with water spray, prevent release of contaminated fire water

Accidental Release Measures

Personal Precautions: Evacuate area, avoid breathing vapors or dust, wear adequate protective equipment
Environmental Precautions: Prevent spill from entering drains, surface water, or groundwater
Methods for Containment and Cleaning: Use inert absorbent (sand, earth), collect in suitable containers for disposal; Wash spill area thoroughly after material pickup; Ventilate area
Emergency Procedures: Restrict entry to unauthorized personnel, remove ignition sources

Handling and Storage

Safe Handling: Handle in well-ventilated areas or fume hoods, minimize dust and vapor formation; Wear protective gloves, goggles, lab coats, avoid contact with skin and eyes
Storage Conditions: Store tightly closed in a cool, dry, well-ventilated space, away from strong bases and oxidizers; Protect from sunlight and moisture
Incompatibilities: Avoid contact with strong bases, oxidizing agents, reducing agents
Hygiene Practices: Wash hands after use, do not eat, drink, or smoke when working with this material

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established limits for this compound; keep exposure as low as possible
Engineering Controls: Use fume hoods or effective local exhaust ventilation to control airborne concentration
Personal Protective Equipment: Safety goggles, chemical-resistant gloves, laboratory coats, respiratory protection if airborne exposure risk exists
Respiratory Protection: Use NIOSH-approved respirator if exposure limits are exceeded or if irritation occurs
Hand Protection: Nitrile or other chemical-resistant gloves
Eye/Face Protection: Safety goggles or full-face shield
Skin Protection: Laboratory apron or chemical-resistant clothing

Physical and Chemical Properties

Appearance: White or off-white solid
Odor: Slight, characteristic odor
Melting Point: Approximately 62-66°C
Boiling Point: Not available due to decomposition
Solubility: Soluble in water, alcohols, and common organic solvents
pH: Acidic in aqueous solution
Vapor Pressure: Not established
Density: About 1.6 g/cm³
Flash Point: Not applicable
Partition Coefficient: Not established
Auto-Ignition Temperature: Not determined
Decomposition Temperature: Data not available
Viscosity: Not relevant (solid at room temperature)

Stability and Reactivity

Chemical Stability: Shows stability under normal conditions; avoid extremes of temperature and light
Reactivity: Reacts with bases, oxidizers, reducers; generates heat and corrosive vapors
Conditions to Avoid: High temperatures, exposure to light, moisture, incompatibles
Hazardous Decomposition Products: Hydrogen bromide, carbon oxides (CO, CO₂)
Polymerization: Not expected to occur
Incompatible Materials: Strong bases, oxidizing and reducing agents

Toxicological Information

Acute Toxicity: Harmful if swallowed, inhaled, or upon contact with skin or eyes
Chronic Effects: May cause severe irritation, tissue damage upon repeated or prolonged contact
Routes of Exposure: Skin, eyes, inhalation, ingestion
Symptoms: Redness, pain, corneal injury, burns, abdominal discomfort
Carcinogenicity: No data indicating carcinogenic potential
Mutagenicity: No available data
Reproductive Toxicity: No available data
Target Organ Effects: Eyes, skin, respiratory tract
LD50/LC50 Values: Not firmly established for humans; animal studies suggest corrosive effects

Ecological Information

Aquatic Toxicity: Data not extensively available; potentially harmful based on structural analogy to similar organic bromines
Biodegradability: Likely to persist in the environment
Bioaccumulative Potential: Possible, based on solubility and persistence
Mobility in Soil: Moderate mobility expected; water solubility suggests some potential to reach ground and surface waters
Other Adverse Effects: Can cause long-term adverse effects in aquatic settings; avoid discharges to the environment

Disposal Considerations

Waste Disposal Methods: Collect and dispose of as hazardous waste in accordance with local, regional, and national regulations
Contaminated Packaging: Treat emptied containers as hazardous, do not reuse, dispose of through licensed hazardous waste contractor
Recommended Disposal: Incineration in approved facility with proper controls
Environmental Precautions: Prevent product and contaminated materials from entering sewers, soil, or natural water bodies

Transport Information

UN Number: 3261
Shipping Name: Corrosive solid, acidic, organic, n.o.s. (contains 2-Bromo-2-methylpropionic acid)
Transport Hazard Class: 8 (Corrosive)
Packing Group: II (medium hazard)
Labels: Corrosive
Special Precautions: Secure tightly, mark container with proper shipping name and UN number, keep away from incompatible materials and food items
Additional Transport Requirements: Notify carrier of corrosive hazard, follow local and international transport regulations

Regulatory Information

Inventory Listings: Present on compliant chemical inventories (e.g., TSCA, EINECS, DSL/NDSL, as required)
SARA Title III: Not considered an extremely hazardous substance or listed in Section 313
OSHA Status: Classified as hazardous
WHMIS Classification: Corrosive material
EU Classification: Corrosive, Harmonized Classification; GHS/CLP compliant
Labeling Compliance: Must use appropriate hazard and precautionary statements on all packaging
Other Relevant Regulation: Comply with specific country and regional requirements regarding storage, labeling, workplace exposure, and environment