Material Safety Data Sheet: 1-Chlorododecane

Identification

Product Name: 1-Chlorododecane
Chemical Family: Alkyl halides
Chemical Formula: C12H25Cl
CAS Number: 112-52-7
Synonyms: Dodecyl chloride
Recommended Use: Intermediate in organic synthesis, chemical research, specialty surfactants
Supplier: Chemical manufacturer contact—Always have emergency phone details at hand
Emergency Telephone: Local poison center, fire department, company hotline

Hazard Identification

Classification: Flammable Liquids (Category 4), Skin Irritant (Category 2), Eye Irritant (Category 2), Acute Toxicity Oral (Category 4)
Label Elements: Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, may be harmful if swallowed or inhaled, can cause respiratory tract irritation
Precautionary Statements: Wear gloves and eye protection, avoid breathing vapors, wash hands thoroughly after handling, do not eat, drink, or smoke while using
Pictograms: Exclamation mark, health hazard
Target Organs: Respiratory system, skin, eyes
Other Hazards: May form flammable vapor-air mixtures, environmental hazard due to persistence in aquatic systems

Composition / Information on Ingredients

Chemical Name: 1-Chlorododecane
Percentage: > 98% by weight
Impurities: Mixtures could contain lesser homologs or dodecane
Other Components: No significant non-hazardous ingredients identified in commercial product

First Aid Measures

Inhalation: Remove exposed person to fresh air, keep at rest, provide oxygen if breathing difficulties develop. Seek medical attention if symptoms persist.
Skin Contact: Wash affected area with soap and water. Remove contaminated clothing and wash before reuse. Seek medical advice for persistent irritation.
Eye Contact: Rinse eyes cautiously with water for at least 15 minutes, lifting eyelids occasionally. Remove contact lenses if present and easy to do. Seek medical attention if irritation develops.
Ingestion: Do not induce vomiting. Rinse mouth with water, never give anything by mouth to an unconscious person. Get medical help immediately.
Most Important Symptoms and Effects: May include reddening of skin, eye redness, throat irritation, headache, nausea, dizziness. Prolonged exposure can lead to central nervous system depression.
Notes for Medical Personnel: Provide symptomatic and supportive care. Monitor respiratory and cardiac function. Treat as hydrocarbon exposure.

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray (fog), foam, dry chemical, carbon dioxide. Avoid high-pressure water jets that spread the material.
Specific Hazards: May produce hydrogen chloride and phosgene gas under fire conditions. Combustible vapor formation possible.
Protective Equipment for Firefighters: Self-contained breathing apparatus and full protective gear.
Special Procedures: Withdraw personnel to safe distance. Cool containers with water spray even after fire is out. Avoid running off contaminated water.

Accidental Release Measures

Personal Precautions: Use protective gloves, safety goggles, impervious clothing. Ensure adequate ventilation.
Evacuation Procedures: Remove non-essential personnel. Isolate area and restrict access.
Environmental Precautions: Prevent entry into waterways, sewers, and soil. Notify relevant authorities if environment is contaminated.
Containment: Absorb spills with inert material such as sand or earth. Use spark-proof tools.
Cleanup Methods: Sweep up and place in sealable containers for proper disposal. Wash spill area with detergent and water.
Disposal: Dispose of spilled material in accordance with local, regional, national regulations.

Handling and Storage

Handling: Avoid direct contact with skin and eyes. Do not eat, drink, or smoke in work area. Maintain good industrial hygiene. Prevent vapor formation in enclosed areas.
Measures for Safe Handling: Ground and bond containers for liquid transfer. Avoid release to environment.
Storage: Store in tightly sealed containers in cool, well-ventilated, dry location. Keep away from direct sunlight, heat sources, and open flames. Segregate from strong oxidizers and acids.
Incompatible Materials: Avoid storage with strong oxidizers, acids, bases, or materials that can promote decomposition.
Other Recommendations: Store in original container; label properly. Limit leaky containers in storage areas.

Exposure Controls and Personal Protection

Occupational Exposure Limits: No official limits established, handle with general industrial hygiene standards.
Engineering Controls: Use fume hood or local exhaust ventilation. Maintain eyewash stations and emergency showers nearby.
Protective Equipment: Chemical-resistant gloves (nitrile, neoprene), safety goggles, lab coat or apron. Respiratory protection if local ventilation is inadequate.
Hygiene Measures: Wash hands, face and exposed skin after handling. Do not reuse contaminated clothing—clean thoroughly.
Environmental Controls: Avoid release into environment, use containment systems for major operations.

Physical and Chemical Properties

Appearance: Clear, colorless to pale yellow liquid
Odor: Slightly sweet, chloroalkane odor
Odor Threshold: Not determined
pH: Not applicable
Melting Point: About -8°C
Boiling Point: 263–265°C
Flash Point: 113°C (closed cup)
Evaporation Rate: Data not available
Flammability: Combustible
Vapor Pressure: Extremely low at room temperature
Vapor Density: Heavier than air
Solubility: Insoluble in water; soluble in organic solvents
Partition Coefficient (n-octanol/water): High log Kow, estimated >6
Autoignition Temperature: 300°C
Decomposition Temperature: Not defined; can decompose under strong heating
Viscosity: Moderate to high

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions.
Reactivity: Not reactive under normal conditions, can form hazardous products at high temperatures.
Possible Hazardous Reactions: Violent reaction with strong oxidizers, possible decomposition by strong bases or acids.
Hazardous Decomposition Products: Hydrogen chloride, phosgene, chlorine, carbon oxides.
Conditions to Avoid: Heat, open flame, spark sources, excessive light.
Incompatible Materials: Strong oxidizing agents, aluminum, potassium, sodium.

Toxicological Information

Likely Routes of Exposure: Inhalation, skin and eye contact, accidental ingestion.
Acute Toxicity: Oral LD50 (rat) estimated around 3000 mg/kg. Inhalation and skin absorption data limited.
Skin Corrosion/Irritation: Causes irritation on contact.
Eye Damage/Irritation: Causes moderate to severe eye irritation.
Sensitization: Not expected to cause skin sensitization.
Repeated Dose Toxicity: Chronic overexposure may impact liver, kidneys, central nervous system.
Carcinogenicity: Not classified as carcinogen by IARC, NTP, or OSHA.
Mutagenicity: Not reported to be mutagenic.
Reproductive Toxicity: No evidence found in literature.
Symptoms: Drowsiness, dizziness, irritation, nausea, headache, dry skin.

Ecological Information

Ecotoxicity: Toxic to aquatic organisms, may cause long-term adverse effects in aquatic environments.
Persistence and Degradability: Not readily biodegradable, tends to persist in water, soil, and sediment.
Bioaccumulative Potential: High due to strong lipophilicity (log Kow >6); potential for accumulation in aquatic life.
Mobility in Soil: Low mobility; likely to adsorb onto soil and sediment.
Other Adverse Effects: No evidence of ozone depletion or global warming potential but accumulates in aquatic food chains.

Disposal Considerations

Disposal Methods: Dispose as hazardous waste by incineration in approved facility. Recycling or recovery not recommended.
Waste Code: As per local and national regulations for chlorinated organic solvents.
Contaminated Packaging: Triple-rinse and dispose via licensed waste contractor.
Precautions: Do not dispose to drains, watercourses, or open environment. Notify authorities for significant spills.

Transport Information

UN Number: 3082
UN Proper Shipping Name: Environmentally hazardous substance, liquid, n.o.s. (contains 1-chlorododecane)
Transport Hazard Class: 9 (Miscellaneous dangerous substances and articles)
Packing Group: III
Labels: Environmental hazard
Marine Pollutant: Yes
Special Precautions: Avoid leakage, use sealed containers. Comply with all national and international transport regulations.
Transport in Bulk: Check with carrier for approved bulk shipment

Regulatory Information

U.S. Regulations: Subject to reporting under CERCLA and SARA Title III for environmental releases; not a specific TSCA-listed compound but covered by chemical inventory laws.
International Regulations: Not listed in Annex I of Regulation (EC) No 850/2004 (POPs Regulation)
Labeling Requirements: Comply with OSHA hazard communication standards; GHS and CLP labeling needed.
Restrictions: Not permitted for direct food or pharmaceutical uses.
Other Regulatory Listings: DSL/NDSL (Canada), EINECS/ELINCS (EU), AICS (Australia), ENCS (Japan)—check national inventories.
Health and Safety Laws: Subject to workplace exposure laws, waste, and spill reporting.