1-Chlorobutane Material Safety Data Sheet (MSDS)

Identification

Product Name: 1-Chlorobutane
Chemical Formula: C4H9Cl
Synonyms: Butyl chloride, n-Butyl chloride
CAS Number: 109-69-3
Recommended Use: Organic solvent, chemical intermediate
Manufacturer: Chemical suppliers and laboratory distributors
Contact for Emergency: Local poison control or emergency response units

Hazard Identification

GHS Classification: Flammable liquids (Category 3), Acute toxicity - oral (Category 4), Skin irritation (Category 2), Eye irritation (Category 2A), Specific target organ toxicity - single exposure (Category 3, narcotic effects)
Hazard Statements: Flammable liquid and vapor, Harmful if inhaled or swallowed, Causes skin and eye irritation, May cause drowsiness or dizziness
Precautionary Statements: Keep away from open flames, hot surfaces, store in tightly closed containers, use personal protective equipment
Pictograms: Flame, Exclamation mark
Signal Word: Warning

Composition / Information on Ingredients

Chemical Name: 1-Chlorobutane
Common Name: n-Butyl chloride
Concentration: >99%
CAS Number: 109-69-3
Impurities: Trace levels of related butyl compounds or water possible depending on manufacturing process

First Aid Measures

Inhalation: Move individual to fresh air, keep warm and at rest, seek medical advice if breathing difficulties persist
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with water for several minutes, seek medical attention if irritation develops
Eye Contact: Rinse immediately with clean water for 15 minutes, hold eyelids open, contact medical professional if symptoms remain
Ingestion: Rinse mouth, do not induce vomiting, offer water to rinse mouth out, obtain urgent medical care
Symptoms: Coughing, irritation of respiratory tract, drowsiness, headache, skin redness, eye discomfort

Fire-Fighting Measures

Suitable Extinguishing Media: Foam, dry chemical powder, carbon dioxide, water spray for cooling only
Unsuitable Extinguishing Media: Strong water jets may spread flames
Special Hazards: Vapors may form explosive mixtures with air, dense vapors travel along ground and can flash back
Hazardous Combustion Products: Hydrogen chloride, carbon monoxide, carbon dioxide
Special Protective Equipment for Firefighters: Self-contained breathing apparatus and full protective gear recommended
Additional Advice: Cool exposed containers with water spray, stay upwind and avoid smoke inhalation

Accidental Release Measures

Personal Precautions: Evacuate unnecessary personnel, ventilate area, avoid sources of ignition, use protective clothing including gloves and goggles
Environmental Precautions: Prevent further leakage, keep out of drains, sewers, surface and ground water
Methods for Cleanup: Absorb with inert material (sand, earth), collect and place in approved containers for disposal, ventilate spill area
Reference to Other Sections: Refer to personal protection and disposal sections for further guidance

Handling and Storage

Safe Handling Advice: Use only in well-ventilated areas, prevent vapor accumulation, ground all equipment, avoid breathing vapors and skin contact, don’t handle near flames or sparks
Hygiene Measures: Wash hands after handling, no eating or drinking during use
Storage Conditions: Keep in tightly closed original containers, store in a cool, dry, and well-ventilated location away from heat and direct sunlight
Incompatible Materials: Strong oxidants, alkali metals, strong bases, aluminum
Storage Class: Flammable liquids

Exposure Controls and Personal Protection

Engineering Controls: Local exhaust or general ventilation to maintain exposure below occupational limits
Exposure Limits: OSHA TWA (not established for 1-chlorobutane; recommend keeping as low as possible), consult local regulations
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), splash-proof safety goggles, flame-retardant clothing, chemical-resistant footwear
Respiratory Protection: Use organic vapor respirators if ventilation is inadequate
Workplace Controls: Emergency eyewash stations and safety showers on site

Physical and Chemical Properties

Appearance: Clear, colorless liquid
Odor: Sharp, sweet ether-like
Odor Threshold: Approximately 1.2 ppm
pH: Not applicable
Melting Point: -123°C
Boiling Point: 78°C
Flash Point: 6°C (43°F)
Evaporation Rate: Moderate compared to ether
Flammability: Easily ignited by heat, sparks, open flames
Explosion Limits: Lower: 1.4%, Upper: 8.1% (in air)
Vapor Pressure: 50 mmHg at 20°C
Vapor Density: 2.9 (air = 1)
Density: 0.88 g/cm³ at 20°C
Solubility in Water: Slight (0.1 g/100 mL at 20°C)
Partition Coefficient (Log Kow): 2.48
Auto-Ignition Temperature: 245°C
Decomposition Temperature: Not specified
Viscosity: 0.41 mPa·s at 20°C

Stability and Reactivity

Chemical Stability: Stable at room temperature under recommended storage and handling procedures
Conditions to Avoid: Heat, sparks, open flames, electrostatic discharge, exposure to moisture
Incompatible Materials: Oxidizers, strong bases, alkali metals, some plastics and rubbers
Hazardous Decomposition Products: Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide
Hazardous Polymerization: Not expected to occur

Toxicological Information

Acute Toxicity: Oral LD50 (rat): 2,500 mg/kg; Dermal LD50 (rat): >2,000 mg/kg; Inhalation LC50 (rat, 4h): 17,100 mg/m³
Potential Health Effects: Short-term: Irritation of skin, eyes, respiratory tract, headache, dizziness
Chronic Exposure: Prolonged or repeated contact may damage liver, kidneys, and central nervous system
Carcinogenicity: Not classified as carcinogen by IARC, NTP, or OSHA
Sensitization: Not expected to cause skin sensitization
Mutagenicity: Limited data, not classified as mutagen
Reproductive Effects: Animal studies inconclusive, no definitive reproductive toxicity

Ecological Information

Ecotoxicity: Harmful to aquatic life, LC50 (fish, 96h): 80 mg/L (rainbow trout)
Persistence and Degradability: Readily biodegradable in soil and water under aerobic conditions
Bioaccumulation Potential: Moderate (Log Kow 2.48), potential for accumulation in aquatic organisms
Mobility in Soil: Mobile in soil, may volatilize from surface water
Other Adverse Effects: Ozone depletion potential: Not considered significant

Disposal Considerations

Waste Treatment Methods: Incinerate under controlled conditions in compliance with local, state, and national regulations
Disposal of Containers: Triple-rinse containers, puncture and deliver to hazardous waste facility
Precautions for Disposal: Do not release into sewers, waterways, or soil; ensure waste handlers wear proper protective gear
Regulatory Waste Codes: U056 (EPA hazardous waste code for 1-chlorobutane)

Transport Information

UN Number: UN1127
Proper Shipping Name: Butyl chlorides
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: II (medium danger)
Labels Required: Flammable liquid
Marine Pollutant: Not classified as marine pollutant
Special Precautions: Ship only in approved containers, segregate from incompatible substances
Domestic and International Regulations: DOT, IMDG, IATA compliant shipping required

Regulatory Information

TSCA Inventory: Listed
EINECS Number: 203-691-9
REACH Status: Registered or pre-registered, subject to restrictions in some jurisdictions
OSHA Hazards: Flammable liquid, harmful by inhalation, skin and eye irritant
SARA Title III Sections 302/304: Not listed as extremely hazardous
SARA Title III Section 313: Not subject to reporting
California Proposition 65: Not listed
Other National Regulations: Check local and national chemical inventories and workplace safety rules