Material Safety Data Sheet for 1-Bromohexadecane

1. Identification

Product Name: 1-Bromohexadecane
Chemical Formula: C₁₆H₃₃Br
Synonyms: Hexadecyl bromide, n-Hexadecyl bromide
CAS Number: 112-86-7
Recommended Use: Intermediate for organic synthesis, used in chemical research and production
Manufacturer/Supplier: Details available on manufacturer’s label or supply chain documentation
Emergency Contact Number: Refer to local/regional poison control or safety hotlines.

2. Hazard Identification

Classification: Causes skin and eye irritation; may cause respiratory tract irritation; aquatic toxicity possible
Pictogram: Exclamation mark, Environment symbol
Signal Word: Warning
Hazard Statements: H315: Causes skin irritation; H319: Causes serious eye irritation; H335: May cause respiratory irritation; H411: Toxic to aquatic life with long lasting effects
Precautionary Statements: Avoid breathing vapors, mist, or spray; Wear protective gloves and eyewear; Wash thoroughly after handling; Avoid release to environment.

3. Composition / Information on Ingredients

Chemical Name: 1-Bromohexadecane
Concentration: >98% (by weight)
CAS Number: 112-86-7
Hazardous Components: No other significant hazardous components reported in high purity material.

4. First Aid Measures

Inhalation: Remove person to fresh air, keep at rest; seek medical attention if symptoms persist.
Skin Contact: Wash skin promptly with soap and water, remove contaminated clothing and wash before reuse; seek medical help if irritation develops.
Eye Contact: Rinse cautiously with water for at least 15 minutes, remove contact lenses if present and easy to do, continue rinsing and get medical attention without delay.
Ingestion: Rinse mouth; do not induce vomiting unless directed by medical personnel; seek immediate medical advice.

5. Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam, sand; avoid direct water jet.
Special Hazards: Thermal decomposition produces hydrogen bromide, bromine fumes, and irritating gases.
Protective Equipment: Firefighters require self-contained breathing apparatus and chemical protective gear.
Specific Procedures: Move containers from area if safe; cool exposed containers with water spray.

6. Accidental Release Measures

Personal Precautions: Use proper personal protective gear (gloves, goggles, lab coat); avoid breathing vapors.
Environmental Precautions: Prevent further leakage or spillage if safe; do not allow material to enter drains, sewers, or watercourses.
Methods for Cleanup: Absorb with inert sand or earth, collect in tightly sealed containers for disposal; ventilate spill area well.

7. Handling and Storage

Handling: Avoid contact with skin, eyes, and clothing; use with adequate ventilation or fume hood; keep away from sources of ignition or heat.
Storage: Store in tightly closed containers in a cool, dry, and well-ventilated place, away from incompatible substances and direct sunlight; recommended temperature: between 2°C and 8°C.

8. Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limits established for 1-bromohexadecane at national or international level.
Engineering Controls: Laboratory fume hood strongly advised; mechanical exhaust as needed to control vapor build-up.
Personal Protection: Chemical splash goggles, compatible gloves (nitrile or neoprene), laboratory coats, and, where exposure risk is significant, respiratory protection conforming to recognized standards.
Hygiene Measures: Wash hands after handling, do not eat, drink, or smoke in work areas, remove contaminated clothing and wash before reuse.

9. Physical and Chemical Properties

Appearance: Colorless to pale yellow oily liquid
Odor: Faint, characteristic organic odor
Boiling Point: 349°C (660°F) at 760 mmHg
Melting Point: 20°C (68°F)
Flash Point: >110°C (230°F) (closed cup)
Vapor Pressure: Negligible at room temperature
Solubility: Insoluble in water; soluble in chloroform, alcohol, and most organic solvents
Density: 1.045–1.055 g/cm³ at 25°C
Viscosity: High (oily) at ambient temperatures
pH: Not applicable (non-aqueous)

10. Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions.
Reactivity: Strong alkalis and strong oxidizers react vigorously; may form explosive mixtures with oxidizers.
Hazardous Decomposition Products: Hydrogen bromide, bromine, carbon oxides form during thermal decomposition or combustion.
Conditions to Avoid: Open flames, sources of heat, exposure to moisture.

11. Toxicological Information

Acute Toxicity: Data limited; estimated low to moderate acute toxicity.
Routes of Exposure: Skin, eye contact, inhalation, ingestion.
Symptoms: Irritation of skin, eyes, and respiratory tract; possible headache, dizziness, or nausea if inhaled in amounts sufficient to cause discomfort.
Chronic Effects: Data unavailable for chronic exposure; long-chain alkyl bromides generally poorly absorbed through skin, but repeated exposure increases irritation risk.
Carcinogenicity, Mutagenicity, Teratogenicity: No long-term studies in humans; available animal data insufficient for hazard assignment.
Sensitization: Not expected to be a skin sensitizer.

12. Ecological Information

Ecotoxicity: Toxic to aquatic organisms; may cause long-term adverse effects in the aquatic environment.
Persistence and Degradability: Low biodegradability predicted; breaks down slowly under environmental conditions.
Bioaccumulation: May bioaccumulate due to strong lipophilicity (Log Kow > 6).
Mobility in Soil: Expected to be immobile due to low water solubility and high partition coefficient.
Other Adverse Effects: Avoid discharge to natural waters; significant spills can damage aquatic ecosystems.

13. Disposal Considerations

Waste Handling: Dispose of in accordance with local, regional, national, and international regulations.
Unused Material: Send to licensed hazardous waste disposal facility.
Contaminated Packaging: Treat as hazardous waste, rinse containers thoroughly before disposal or recycling if permitted.
Precautions: Do not discharge to sewers, surface waters, or groundwaters; ensure containment to prevent environmental release.

14. Transport Information

UN Number: UN3082
Proper Shipping Name: Environmentally hazardous substance, liquid, n.o.s. (1-Bromohexadecane)
Transport Hazard Class: 9 (Miscellaneous dangerous goods)
Packing Group: III
Special Precautions: Use compliant, correctly labeled containers; secure loads during transit.
Marine Pollutant: Yes

15. Regulatory Information

Global Inventories: Listed in TSCA (United States), EINECS (EU), DSL (Canada), AICS (Australia), and similar inventories worldwide.
Hazard Codes: Xi (Irritant), N (Dangerous for the environment)
Labeling Requirements: Hazard pictograms, risk phrases R38 (irritating to skin), R51/53 (toxic to aquatic organisms, may cause long-term adverse effects), and safety phrases S24/25 (avoid contact with skin and eyes), S61 (avoid release to the environment).
Regulatory Restrictions: Handle in accordance with all relevant local and international chemical safety, hazard communication, and environmental protection regulations.
Other Notifications: Safety assessment available from supplier or competent local authority.