Material Safety Data Sheet: 1-Bromoheptane

Identification

Chemical Name: 1-Bromoheptane
Synonyms: n-Heptyl bromide
CAS Number: 629-04-9
Recommended Use: Organic synthesis, intermediate in pharmaceutical and chemical industries
Supplier: Refer to packaging label or purchasing documents for supplier information
Emergency Contact: Refer to local emergency numbers or chemical safety hotline

Hazard Identification

Classification: Flammable liquid, acute toxicity (oral, dermal, inhalation), skin and eye irritant
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, harmful if swallowed, may cause respiratory irritation, flammable liquid and vapor
Pictograms: Health hazard, exclamation mark, flame
Precautionary Statements: Avoid breathing vapors, wear protective gear, keep away from sparks and open flames, wash hands thoroughly after use, do not eat or drink when using this product
Potential Health Effects: Short-term exposure can cause irritation to skin, eyes, and respiratory tract; ingestion or inhalation may cause central nervous system depression, gastrointestinal upset, and pulmonary symptoms

Composition / Information on Ingredients

Chemical identity: 1-Bromoheptane
Concentration: ≥98%
Impurities: Trace amounts of heptanol, heptene, or related hydrocarbons (typically <2%)
Decomposition Products: Hydrogen bromide, bromine compounds, carbon oxides during combustion or extreme heating

First Aid Measures

Inhalation: Remove person to fresh air, provide oxygen if breathing becomes labored, medical attention if symptoms persist
Skin Contact: Wash exposed area with plenty of water and mild soap, remove contaminated clothing and shoes, seek medical attention for persistent irritation
Eye Contact: Rinse eyes cautiously with water for several minutes, remove contact lenses if present, continue rinsing, immediate medical attention recommended
Ingestion: Rinse mouth with water, do not induce vomiting, seek immediate medical care
Most Important Symptoms: Burning sensation, redness, coughing, shortness of breath, headache
Notes to Physician: Provide symptomatic treatment, monitor for respiratory symptoms or systemic effects

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical, foam, water spray (to cool containers only)
Unsuitable Media: Do not use direct stream of water, may spread fire
Fire Hazards: Vapors are heavier than air, may accumulate in low areas and ignite explosively, exposure to fire can release toxic hydrogen bromide and carbon oxides
Special Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective gear
Special Precautions: Evacuate area, fight fire from safe distance, use water spray to cool containers, prevent fire-fighting runoff from entering drains or waterways

Accidental Release Measures

Personal Precautions: Evacuate non-essential personnel, ventilate area, avoid contact with spilled material, use appropriate personal protective equipment
Environmental Precautions: Prevent release into drains, surface waters, or soil, inform authorities in event of significant spill
Clean-up Methods: Absorb liquid with inert material (sand, earth), collect into suitable container for disposal, ventilate contaminated area, wash residual spill with water and detergent

Handling and Storage

Handling: Work in well-ventilated areas, ground and bond containers to prevent static buildup, avoid inhalation and skin contact, do not smoke or use open flame near product
Storage: Store in tightly sealed original container, keep away from heat, sparks, and direct sunlight, separate from oxidizers, acids, and sources of ignition, store in cool, dry location with secondary containment

Exposure Controls and Personal Protection

Engineering Controls: Use local exhaust ventilation, process enclosures, and explosion-proof equipment in areas where vapors may accumulate
Personal Protective Equipment (PPE): Chemical-resistant gloves (e.g., nitrile), safety goggles or face shield, flame-resistant lab coat, impervious boots, suitable respiratory protection if airborne concentrations exceed occupational exposure limits
Exposure Limits: No specific threshold limit value (TLV) established, use as low as reasonably achievable approach due to irritation potential
Hygiene Measures: Wash hands and face thoroughly before breaks and after handling, remove and wash contaminated clothing before reuse

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Mild, sweet odor
Molecular Formula: C7H15Br
Molecular Weight: 179.10 g/mol
Melting Point: -66°C
Boiling Point: 180–181°C
Flash Point: 68–72°C (closed cup)
Density: 1.164–1.172 g/cm³ at 20°C
Solubility: Insoluble in water, soluble in common organic solvents
Vapor Pressure: 2.5 mmHg at 25°C
Auto-ignition Temperature: Data not specified, handle away from direct ignition sources
Partition Coefficient (log Kow): Approximately 4.2

Stability and Reactivity

Stability: Stable under recommended storage and handling conditions
Incompatible Materials: Strong oxidizers, acids, alkali metals, reducing agents
Hazardous Decomposition Products: Releases hydrogen bromide, bromine, and carbon oxides under fire conditions
Reactivity: Reacts with strong bases, may undergo halogen exchange or elimination reactions under extreme conditions
Hazardous Polymerization: Will not occur under normal processing

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin; causes local irritation and possible systemic effects such as drowsiness, nausea, and headache
Skin and Eye Irritation: Irritating to skin and eyes; prolonged exposure may lead to dryness or chemical burns
Sensitization: No reliable data on sensitizing effects
Chronic Effects: Repeated or prolonged exposure may cause damage to the central nervous system and liver; no evidence for carcinogenic, mutagenic, or reproductive toxicity in available literature
Specific Target Organ Toxicity: May cause transient central nervous system depression at high concentrations

Ecological Information

Aquatic Toxicity: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Not readily biodegradable, persists in soil and water
Bioaccumulative Potential: High potential, log Kow indicates potential to bioaccumulate in aquatic organisms
Mobility in Soil: Low mobility due to hydrophobic properties, may bind to organic matter
Other Adverse Effects: Discharge to the environment should be avoided; follow best practices for containment and disposal

Disposal Considerations

Waste Treatment Methods: Collect and dispose of in accordance with national, regional, and local regulations, incineration in licensed facility preferred
Disposal of Containers: Triple rinse containers, puncture or cut to prevent re-use, send to legal hazardous waste facility
Special Precautions: Do not allow product to reach sewage system or natural water sources, handle waste under certified personnel supervision

Transport Information

UN Number: 2810
UN Proper Shipping Name: Toxic liquid, organic, n.o.s. (1-Bromoheptane)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Marine Pollutant: Yes
Special Precautions for Transport: Keep container tightly closed, ensure package is undamaged, secure containers for transport, follow all applicable road, rail, air, and sea regulations

Regulatory Information

International Inventories: Listed on TSCA (US), EINECS/ELINCS (EU), DSL (Canada), AICS (Australia)
SARA Title III (Sections 302/304/311/312/313): Not listed as an extremely hazardous substance; subject to reporting for hazardous chemicals
California Proposition 65: No component listed as known to cause cancer or reproductive toxicity
Workplace Exposure Standard: No established OSHA PEL or ACGIH TLV; recommend industrial hygiene monitoring
Other Regulations: Subject to chemical hygiene plans and local occupational health requirements, consult regional authorities for specific restrictions and requirements
Labeling Requirements: GHS compliant labeling required for all containers