MSDS for 1-Bromo-4-Chlorobutane

Identification

Product Name: 1-Bromo-4-Chlorobutane
Chemical Formula: C4H8BrCl
Synonyms: 4-Chlorobutyl bromide, 1-Chloro-4-bromobutane
CAS Number: 6940-78-9
Manufacturer: Chemical companies specializing in halogenated organics
Recommended Use: Laboratory chemicals, organic synthesis
Emergency Contact: Emergency numbers are usually provided by manufacturers, relevant local poison control contacts

Hazard Identification

Classification: Acute toxicity (oral, dermal), Skin irritation, Eye irritation
Signal Word: Warning
Hazard Statements: Harmful if swallowed, toxic if inhaled, causes skin and eye irritation, may cause respiratory tract irritation
Precautionary Statements: Do not breathe dust or vapors, wash hands thoroughly after handling, use in a well-ventilated area, avoid release to the environment, wear protective gloves and eye/face protection
GHS Pictograms: Skull and crossbones, Exclamation mark

Composition / Information on Ingredients

Chemical: 1-Bromo-4-Chlorobutane
Concentration: ≥98% by weight
Impurities: Trace amounts of related halogenated butanes may be present/introduced during production
Other Information: Chemical exists as a clear, colorless to pale yellow liquid, halogenated hydrocarbon

First Aid Measures

Inhalation: Remove affected person to fresh air, keep at rest, call poison control or seek emergency medical attention if symptoms appear such as coughing, headache, or shortness of breath
Skin Contact: Immediately wash with plenty of soap and water for at least 15 minutes, remove contaminated clothing, seek medical attention if irritation develops
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, get immediate medical attention if irritation persists
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical advice or call poison control immediately
Most Important Symptoms: Burning sensation, cough, nausea, headache, skin redness, eye watering and redness

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, alcohol-resistant foam; do not use straight water streams due to risk of spreading
Unsuitable Extinguishing Media: Water may not be effective
Specific Hazards: May produce toxic gases such as hydrogen chloride, hydrogen bromide, and carbon oxides during combustion
Special Protective Equipment for Firefighters: Firefighters should wear self-contained breathing apparatus and full protective gear
Explosion Data: Vapors may form explosive mixtures with air; containers may rupture under fire conditions

Accidental Release Measures

Personal Precautions: Wear chemical-resistant gloves and goggles, use respiratory protection if ventilation is not adequate, remove all sources of ignition
Environmental Precautions: Prevent further leakage or spillage if safe to do so, do not allow to enter drains, groundwater, or soil
Methods for Cleaning Up: Absorb spill with inert material such as sand or vermiculite, collect in tightly closed containers for proper disposal, ventilate area, wash spill site after material pick-up
Small Spills: Mop up or collect with non-sparking tools
Large Spills: Contain run-off, consult environmental response teams or authorities

Handling and Storage

Handling: Wear appropriate personal protective equipment including lab coats, goggles, and impervious gloves, use only in a chemical fume hood or well-ventilated area, avoid ingestion and inhalation, avoid contact with skin, eyes, and clothing, keep away from heat, sparks, and open flame
Storage: Store in a tightly closed container, keep in a dry, cool, well-ventilated area, segregate from incompatible materials such as strong oxidizers, bases and acids, label storage area for hazardous chemicals, keep away from direct sunlight and ignition sources
Special Considerations: Regularly check containers for signs of leaking or corrosion, store at recommended temperatures to avoid degradation of the product

Exposure Controls and Personal Protection

Engineering Controls: Use in certified chemical fume hoods, install local exhaust ventilation at sources of vapor or mist
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene recommended), safety goggles or face shield, flame resistant lab coat, closed-toe shoes
Respiratory Protection: Use approved respirator equipment if exposure limits are exceeded or ventilation is inadequate
Occupational Exposure Limit: No established OSHA/ACGIH limits; exposure should be kept as low as reasonably achievable
Hygiene Measures: Wash thoroughly after handling, avoid touching face with contaminated gloves, do not eat, drink, or smoke in chemical use areas

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Sharp, irritating odor
Melting Point: -65°C
Boiling Point: 165-167°C
Flash Point: 57°C (closed cup, approximate)
Autoignition Temperature: Data not widely reported, but likely above 200°C
Solubility: Insoluble in water, miscible with most organic solvents
Density: 1.47 g/cm³ at 25°C
pH: Not applicable (neutral compound)
Vapor Pressure: Relatively low at room temperature
Vapor Density: Heavier than air
Partition Coefficient: Log Kow not widely published, but will favor partitioning into organic phases

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Reacts vigorously with strong oxidizers, bases, or reducing agents
Hazardous Decomposition Products: Produces hydrogen chloride, hydrogen bromide, and carbon oxides when heated to decomposition
Conditions to Avoid: Exposure to heat, flames, sources of ignition, contact with incompatible chemicals
Incompatible Materials: Strong alkalis, strong acids, oxidants, reducing agents, finely powdered metals

Toxicological Information

Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin, causes moderate to severe irritation to skin and eyes
Skin/Eye Irritation: Direct contact results in irritation, redness, and possibly chemical burns
Inhalation Effects: Inhalation of vapors can lead to airway irritation, lung inflammation, dizziness, and headache
Ingestion Effects: May cause gastrointestinal distress, nausea, vomiting
Chronic Exposure: Frequent or prolonged contact may damage the liver and kidneys, repeated skin exposure leads to dermatitis
Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic by IARC, NTP, or OSHA
Sensitization: Skin and respiratory sensitization not reported in literature at low exposures, but potential cannot be ruled out without further data

Ecological Information

Ecotoxicity: Expected to be toxic to aquatic life based on structure and related halogenated solvents
Persistence and Degradability: Relatively persistent, breaks down slowly in the environment, hydrolysis can be slow
Bioaccumulative Potential: May bioaccumulate in aquatic organisms, log Kow suggests some potential for partitioning into biota
Mobility in Soil: Low water solubility limits movement through soil, tends to remain in sediment and organic matter
Other Adverse Effects: Can contribute to ozone depletion and indirect greenhouse gas effects if released in large quantities

Disposal Considerations

Disposal Methods: Dispose of material and contaminated container in accordance with local, regional, and national regulations, incinerate in a chemical incinerator equipped with flue gas scrubber, avoid discharge to the environment
Prohibited Disposal: Do not pour into drains, surface water, or soil
Empty Containers: Should be triple-rinsed, labels removed before recycling or disposal, puncture and destroy to avoid unauthorized reuse

Transport Information

UN Number: 2810
UN Proper Shipping Name: Toxic Liquid, Organic, N.O.S. (contains 1-Bromo-4-Chlorobutane)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Hazard Labels: Toxic
Marine Pollutant: Yes
Special Precautions: Keep separated from incompatible substances, avoid rough handling and heat during transport, use tightly sealed original containers

Regulatory Information

TSCA Status: Listed in the United States Toxic Substances Control Act Inventory
REACH Registration: Pre-registered – check for updates on European Chemicals Agency resources
SARA Title III: Contains hazardous substances as per Section 313 (reportable depending on quantity)
OSHA Hazard Communication: Classified as hazardous chemical
WHMIS Classification: D1B (Toxic material causing immediate and serious toxic effects), D2B (Material causing other toxic effects)
Other Regulations: Subject to appropriate workplace labeling, storage requirements, and health and safety rules as established by national and regional authorities