Material Safety Data Sheet: 1-Bromo-3-Methylbutane

Identification

Product Name: 1-Bromo-3-methylbutane Chemical Formula: C5H11Br Synonyms: Isoamyl bromide CAS Number: 107-82-4 Recommended Use: Laboratory organic synthesis, pharmaceuticals, chemical research Supplier: [Contact details of manufacturer or distributor] Emergency Contact: [24-hour emergency phone number]

Hazard Identification

Hazard Classification: Flammable liquid, skin irritant, causes eye irritation, suspected of causing respiratory irritation GHS Label Elements: Signal word: Warning; Hazard pictograms: flame, exclamation mark Hazard Statements: May cause skin and eye irritation, may cause respiratory irritation, flammable liquid and vapor Precautionary Statements: Avoid contact with eyes, skin, and clothing; keep away from heat, sparks, and open flames; use only in well-ventilated areas Target Organs: Skin, eyes, respiratory system Potential Health Effects: Inhalation may irritate respiratory tract; skin absorption possible, skin and eye irritation common after exposure NFPA Ratings: Health: 2; Flammability: 2; Reactivity: 0

Composition / Information on Ingredients

Chemical Name: 1-Bromo-3-methylbutane CAS Number: 107-82-4 Concentration: 98-100% Impurities: May contain trace amounts of other alkyl bromides (<2%) Other Additives: None normally present

First Aid Measures

Eye Contact: Rinse immediately with plenty of clean water for at least 15 minutes, keep eyelids open, seek immediate medical help Skin Contact: Remove contaminated clothing, wash affected area with soap and water, consult medical assistance if irritation persists Inhalation: Move person to fresh air, if breathing is difficult seek medical attention, apply artificial respiration if necessary Ingestion: Do not induce vomiting, rinse mouth thoroughly, get medical advice promptly Most Important Symptoms/Effects: Redness, burning sensation in eyes, skin; coughing, throat discomfort when inhaled

Fire-Fighting Measures

Suitable Extinguishing Media: Foam, dry chemical, carbon dioxide, water spray (mist, not jet) Unsuitable Extinguishing Media: Direct water jet Specific Hazards Arising from Chemical: Vapors are heavier than air, may travel to ignition source and flash back, combustion generates toxic fumes including hydrogen bromide and carbon oxides Protective Equipment: Wear self-contained breathing apparatus and protective suit Special Firefighting Procedures: Cool containers with water spray, avoid runoff entering drains or waterways, stay upwind and evacuate area if large fire

Accidental Release Measures

Personal Precautions: Evacuate area, ensure adequate ventilation, avoid breathing vapors, wear appropriate personal protective equipment (PPE) including gloves, goggles, chemical-resistant clothing Environmental Precautions: Prevent further leakage or spillage if safe, do not release into drains or surface water Methods for Containment and Cleanup: Absorb with inert material such as sand or vermiculite, place in suitable closed containers for disposal, wash spill area with detergent and water Small Spills: Absorb and collect with non-combustible absorbent material Large Spills: Dike to prevent spread, collect mechanically, ventilate area thoroughly

Handling and Storage

Safe Handling: Use only in well-ventilated locations, avoid breathing vapors, prevent contact with skin and eyes, keep away from all ignition sources, use spark-proof tools and equipment Storage Conditions: Store in tightly closed containers in a cool, dry, well-ventilated area away from direct sunlight, incompatible substances (strong oxidizers, acids, bases), and ignition sources Incompatibilities: Avoid strong oxidizing agents, strong acids, and strong bases Storage Temperature: Recommended below 25°C Special Precautions: Keep container upright and tightly sealed to prevent leaks, ensure proper labeling

Exposure Controls and Personal Protection

Exposure Limits: No established occupational exposure limits; handle as hazardous via effective engineering controls Engineering Controls: Local exhaust ventilation or fume hood usage strongly suggested Personal Protective Equipment: Gloves: Chemical-resistant recommended (nitrile, neoprene) Eye Protection: Safety goggles or face shield Skin Protection: Lab coat, apron, chemical-resistant shoes Respiratory Protection: If ventilation is inadequate, use suitable respirator with organic vapor cartridge Hygiene Measures: Do not eat, drink, or smoke during handling, wash hands after use, remove contaminated clothing immediately

Physical and Chemical Properties

Appearance: Colorless to pale yellow, clear liquid Odor: Pungent, sweetish odor Melting Point: -90°C Boiling Point: 118-120°C Flash Point: 34°C (closed cup) Autoignition Temperature: 250°C Explosive Limits: No data available Vapor Pressure: 20 mmHg at 20°C Vapor Density: 4.7 (air = 1) Density: 1.19 g/cm³ at 20°C Solubility: Insoluble in water, soluble in most organic solvents Partition Coefficient (n-octanol/water): 2.85 Viscosity: Low, flows easily Molecular Weight: 151.05 g/mol

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions Conditions to Avoid: Excess heat, open flames, static discharge, strong light Materials to Avoid: Strong oxidizers, acids, bases, reducing agents Decomposition Products: Hydrogen bromide, carbon monoxide, carbon dioxide Hazardous Reactions: Potential formation of toxic gases if involved in fire Polymerization: Will not occur under normal conditions

Toxicological Information

Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion Acute Effects: Skin and eye irritation, respiratory tract irritation, headache, dizziness, nausea from inhalation Chronic Effects: Prolonged or repeated exposure may cause dermatitis, possible damage to nervous system in high exposures Toxicity Data: LD50 (oral, rat): 3150 mg/kg; LD50 (dermal, rabbit): not available; LC50 (inhalation, rat): not available Carcinogenicity: No specific classification by IARC, NTP, or OSHA Mutagenicity: No available data Sensitization: No information indicating sensitizing potential

Ecological Information

Aquatic Toxicity: Harmful to aquatic life, may cause long-term adverse effects in the aquatic environment Persistence and Degradability: Not readily biodegradable, may persist in soil and water Bioaccumulation Potential: Moderate bioaccumulation based on partition coefficient Mobility in Soil: Not highly mobile, tends to bind to organic material Other Adverse Effects: Avoid release to the environment to prevent contamination of water sources

Disposal Considerations

Waste Disposal: Manage as hazardous waste, use licensed chemical waste disposal contractor Container Disposal: Do not reuse empty containers, triple-rinse and deliver containers to approved drum reconditioner or disposer Environmental Impact: Prevent entry into sewers or natural waters, incinerate in accordance with local, regional, and national regulations Regulatory Requirements: Comply with hazardous waste regulations appropriate to local and federal standards

Transport Information

UN Number: UN 2342 Proper Shipping Name: 1-Bromo-3-methylbutane Transport Hazard Class: 3 (Flammable liquids) Packing Group: III Labels Required: Flammable liquid Marine Pollutant: Yes Special Precautions: Secure tightly sealed drums upright, segregate from oxidizing materials

Regulatory Information

OSHA: Hazardous chemical, subject to Hazard Communication Standards TSCA Inventory: Listed SARA Title III: Not classified as extremely hazardous, but included for reporting under Section 311/312 California Proposition 65: Not listed as a carcinogen or reproductive toxin EU Regulations: REACH registered, classified under EC No 1272/2008 as flammable liquid and irritant WHMIS (Canada): Class B2 (Flammable), D2B (Toxic) Other Regulatory Status: Handle according to all applicable regulations, ensuring appropriate training for personnel