MSDS of 1,6-Dichlorohexane

Identification

Product Name: 1,6-Dichlorohexane
Chemical Formula: C6H12Cl2
Chemical Family: Aliphatic chlorinated hydrocarbon
Synonyms: Hexamethylene dichloride, Hexane-1,6-diyl dichloride
CAS Number: 2163-00-0
Intended Use: Laboratory chemicals, intermediates for chemical synthesis
Supplier Details: Manufacturer’s address, phone number, and emergency contact info provided on corporate safety data sheet
Recommended Use Restrictions: Industrial and professional use only, not for food, drug, or home use

Hazard Identification

Classification: Flammable liquid, skin irritant, possible eye irritant, potential environmental hazard
GHS Pictograms: Flame, exclamation mark
Signal Word: Warning
Hazard Statements: Causes skin irritation, may cause respiratory irritation, harmful if swallowed, suspected of causing genetic defects
Precautionary Statements: Avoid breathing vapors, wear protective gloves and eye protection, store in well-ventilated area, do not release to environment
Exposure Routes: Inhalation, skin and eye contact, ingestion
Emergency Overview: Clear, colorless liquid, pungent odor, can impact the central nervous system if inhaled in high concentrations

Composition / Information on Ingredients

Chemical Name: 1,6-Dichlorohexane
Concentration: > 98% by weight
Impurities: Water (<1%), possible trace organic halides
Molecular Weight: 155.06 g/mol
EINECS number: 218-488-2

First Aid Measures

Inhalation: Remove person to fresh air, provide oxygen if breathing is difficult, seek medical attention if symptoms persist
Skin Contact: Wash affected area with plenty of soap and water, remove contaminated clothes, get medical advice for persistent irritation or blistering
Eye Contact: Rinse eyes cautiously with water for at least 15 minutes, lifting upper and lower eyelids occasionally, get prompt medical attention if discomfort continues
Ingestion: Do not induce vomiting, rinse mouth with water, never give anything by mouth to an unconscious person, seek immediate medical advice
Most Important Symptoms: Redness, burning sensation, headache, dizziness, possible shortness of breath or gastrointestinal discomfort
Immediate Medical Care and Special Treatment: Treat symptomatically, monitor for respiratory complications

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide
Unsuitable Extinguishing Media: Direct water jet may spread the fire
Hazardous Combustion Products: Hydrogen chloride, carbon oxides, phosgene under fire conditions
Special Protective Equipment for Firefighters: Self-contained breathing apparatus and full protective clothing
Fire and Explosion Hazards: Vapors can form explosive mixtures in air, containers may rupture due to pressure build-up, runoff to sewer may create fire or explosion hazard
Advice for Firefighters: Keep containers cool with water spray, approach from upwind to avoid vapors

Accidental Release Measures

Personal Precautions: Avoid contact with skin and eyes, ventilate the area, remove ignition sources, use appropriate personal protective equipment
Environmental Precautions: Prevent product from entering drains, waterways, or soil
Spill Containment: Contain spillage, absorb with inert material (sand, earth), avoid generating dust or vapor
Clean-up Procedures: Collect spill in suitable container for safe disposal, clean affected area thoroughly with water and detergent
Emergency Procedures: Evacuate unprotected personnel from spill area, alert emergency services if needed

Handling and Storage

Precautions for Safe Handling: Use only in well-ventilated areas, avoid inhalation of vapors, prevent static discharge, no smoking or open flames in work area
Hygiene Measures: Wash thoroughly after handling, avoid eating, drinking, or smoking in work area, keep work clothing separate
Conditions for Safe Storage: Store in original, tightly closed containers in cool, dry, and well-ventilated place, segregate from incompatible materials such as strong oxidizers and acids
Incompatibility: Strong bases, oxidizing agents, aluminum and other soft metals
Storage Temperature: Store between 2–8°C for maximum stability, protect from direct sunlight

Exposure Controls and Personal Protection

Engineering Controls: Use local exhaust ventilation to maintain airborne concentrations below limits, provide eyewash and safety shower stations
Occupational Exposure Limits: No ACGIH or OSHA established limits; handle as a hazardous chemical
Respiratory Protection: Use NIOSH-approved organic vapor respirator if exposure exceeds limits or if ventilation is inadequate
Skin Protection: Wear adequate chemical-resistant gloves (nitrile or neoprene), long sleeves, and impervious protective clothing
Eye Protection: Use safety goggles or full-face shield
Other Protection: Avoid prolonged or repeated contact, change contaminated clothes immediately, practice good industrial hygiene

Physical and Chemical Properties

Appearance: Clear, colorless liquid
Odor: Sharp, chloroform-like scent
Odor Threshold: Not available
pH (at 20°C): Not applicable
Melting Point/Freezing Point: -36°C
Boiling Point: 216–218°C
Flash Point: 91°C (closed cup)
Evaporation Rate: Not determined
Flammability: Combustible under certain conditions
Vapor Pressure: 0.1 mm Hg at 20°C
Vapor Density: 5.4 (air = 1)
Relative Density: 1.09 at 20°C
Solubility: Insoluble in water, soluble in organic solvents
Partition Coefficient (n-octanol/water): Log Kow estimated at 2.75
Auto-ignition Temperature: 430°C
Decomposition Temperature: Not available
Viscosity: 2.34 mPa·s at 25°C
Molecular Weight: 155.06 g/mol

Stability and Reactivity

Chemical Stability: Stable under standard conditions, may decompose under extreme heat or exposure to light
Reactivity: No hazardous polymerization
Conditions to Avoid: Heat, ignition sources, direct sunlight, exposure to moisture
Incompatible Materials: Strong oxidizing agents, strong bases, alkali metals, aluminum, concentrated acids
Hazardous Decomposition Products: Hydrogen chloride, phosgene gas, carbon monoxide, carbon dioxide
Other Reactivity Information: May form hazardous vapors on reaction with certain metals under high temperature

Toxicological Information

Likely Routes of Exposure: Inhalation, skin, eye contact, ingestion
Acute Toxicity: Oral LD50 (rat): >2,000 mg/kg, Dermal LD50 (rabbit): >2,000 mg/kg
Skin Corrosion/Irritation: Causes moderate to severe irritation
Eye Damage/Irritation: May cause eye redness and watering
Respiratory Sensitization: Possible respiratory irritation at high concentrations
Germ Cell Mutagenicity: Limited data; structurally related substances suspected of mutagenic effects
Carcinogenicity: No clear evidence in animal studies, not listed by IARC, OSHA, or NTP
Reproductive Toxicity: No data available
STOT – Single Exposure: Can cause drowsiness or dizziness
STOT – Repeated Exposure: May cause liver or kidney damage from chronic overexposure
Other Health Effects: Central nervous system effects reported with high vapor concentrations; include headache, nausea, shortness of breath

Ecological Information

Toxicity to Aquatic Life: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Not readily biodegradable, may persist in soil or water for extended periods
Bioaccumulation Potential: Moderate, risk of bioaccumulating in organisms
Mobility in Soil: Low mobility in soil due to hydrophobic nature
Other Ecological Effects: Avoid release into the environment; long-term ecological risks not fully studied

Disposal Considerations

Waste Treatment Methods: Handled as hazardous waste, incineration is a preferred disposal method
Disposal of Product: Dispose of via licensed hazardous waste contractor following local, regional, and national regulations
Disposal of Contaminated Packaging: Rinse empty containers with suitable solvent, recycle or dispose as hazardous waste
Precautions: Avoid discharge into drains or environment, follow all applicable disposal regulations

Transport Information

UN Number: 3082
UN Proper Shipping Name: Environmentally Hazardous Substance, Liquid, N.O.S. (1,6-Dichlorohexane)
Transport Hazard Class: 9 (Miscellaneous hazardous materials)
Packing Group: III
Environmental Hazards: Marine pollutant
Special Precautions for User: Keep container tightly sealed, avoid temperature extremes and sunlight during shipment
Transport Labels: Environmentally hazardous substance label, miscellaneous dangerous goods label required

Regulatory Information

OSHA Compliance: Classified as hazardous under OSHA Hazard Communication Standard (29 CFR 1910.1200)
SARA Title III: Listed under Section 313 for toxic chemical reporting
TSCA Listing: Appears on US TSCA Inventory
DSL/NDSL (Canada): Present
REACH (EU): Registered under REACH Regulation (EC) No 1907/2006
Other International Regulations: Subject to export notification and control in several countries
Other Relevant Legislation: Follow all applicable state and local environmental regulations for handling, storage, and disposal