Material Safety Data Sheet for 1,5-Dichloropentane

Identification

Chemical Name: 1,5-Dichloropentane
Synonyms: Pentamethylene dichloride, Pentane-1,5-dichloride
CAS Number: 111-44-4
Recommended Use: Chemical intermediate, solvent, laboratory reagent
Supplier Details: Manufacturer’s or supplier's name, address, and contact information required for full compliance
Emergency Phone Number: Local emergency contact provided by supplier

Hazard Identification

GHS Classification: Skin Irritant (Category 2), Eye Irritant (Category 2A), Specific Target Organ Toxicity (Single/Repeated Exposure, Category 3)
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation; harmful if inhaled or swallowed; may cause respiratory irritation
Precautionary Statements: Wear protective gloves and eye protection, avoid breathing vapor, use only outdoors or in a well-ventilated area, wash thoroughly after handling, avoid release to the environment
Pictograms: Exclamation mark, Health hazard
Route of Exposure: Inhalation, skin and eye contact, ingestion
Potential Health Effects: Skin redness and irritation, coughing, sore throat, possible headache, eye watering or burning sensation, nausea, and at high exposures depressant effects on central nervous system

Composition / Information on Ingredients

Substance: 1,5-Dichloropentane
Chemical Formula: C5H10Cl2
Concentration: ≥ 99% by weight
Impurities: 1-chloropentane (trace), pentanol isomers (trace), water (≤ 0.1%)

First Aid Measures

Inhalation: Move person to fresh air quickly; keep warm and at rest; seek medical advice if symptoms appear
Skin Contact: Rinse skin immediately with enough water and remove contaminated clothing; wash with soap and plenty of water; medical attention required for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, lift eyelids to ensure thorough flushing, seek medical attention promptly
Ingestion: Rinse mouth thoroughly with water; do not induce vomiting; call poison control and receive medical attention as soon as possible
Symptoms: Skin and eye irritation, headache, dizziness, drowsiness, nausea

Fire-Fighting Measures

Extinguishing Media: Carbon dioxide, dry chemical powder, foam, use fine water spray for cooling only
Unsuitable Extinguishing Media: Direct water jet may spread fire
Specific Hazards: Vapors can form explosive mixtures with air; hazardous decomposition includes hydrogen chloride, phosgene, carbon monoxide, carbon dioxide
Protective Equipment: Wear self-contained breathing apparatus and full protective clothing
Advice for Firefighters: Cool containers with plenty of water; evacuate area if heavy vapor or decomposition fumes develop; prevent runoff from entering waterways

Accidental Release Measures

Personal Precautions: Wear chemical splash goggles, impervious gloves, suitable protective clothing; avoid breathing vapors; ventilate area
Environmental Precautions: Prevent spills from entering drains or surface water; use containment methods to minimize environmental impact
Methods for Cleaning Up: Absorb with inert material (sand, earth, vermiculite), collect in suitable, labeled containers for disposal; clean area with water and detergent after material removal; dispose of all waste according to local regulations

Handling and Storage

Handling Precautions: Use only in well-ventilated areas or under a chemical fume hood; avoid contact with skin, eyes, and clothing; do not breathe vapors or mists; wash hands thoroughly after handling
Storage Conditions: Store in tightly closed, corrosion-resistant container in cool, dry, well-ventilated area away from incompatible materials (oxidizers, acids, bases); protect from moisture and direct sunlight; segregate from food and feedstuffs
Incompatibilities: Strong oxidizing agents, strong acids, strong bases, reducing agents

Exposure Controls and Personal Protection

Occupational Exposure Limits: No national exposure limits established; control exposure through process enclosure or local exhaust ventilation
Personal Protective Equipment: Safety goggles or face shield; chemical-resistant gloves (nitrile, neoprene); full-length lab coat or coveralls; use respiratory protection if exposure limits are exceeded or if ventilation is inadequate
Engineering Controls: Provide general ventilation and local exhaust; emergency eye wash and safety shower station available in the work area

Physical and Chemical Properties

Appearance: Colorless, oily liquid
Odor: Sweet, faint, chloroform-like
pH: Not applicable (neutral in pure state)
Boiling Point: 205°C (401°F)
Freezing Point: -46°C (-51°F)
Flash Point: 92°C (198°F) (closed cup)
Vapor Pressure: 0.42 mmHg at 25°C
Vapor Density: 4.5 (air = 1)
Solubility in Water: Insoluble (<1 mg/L at 20°C)
Specific Gravity: 1.108 at 20°C
Partition Coefficient (log Kow): 3.17
Viscosity: 2.12 mPa·s at 25°C
Evaporation Rate: Not readily available

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions; decomposes at elevated temperature
Hazardous Reactions: Reacts with strong oxidizing agents, acids, and bases, forming toxic gases
Decomposition Products: Hydrogen chloride, carbon monoxide, carbon dioxide, phosgene under fire conditions
Conditions to Avoid: Excess heat, sources of ignition, incompatible substances, direct sunlight, moisture

Toxicological Information

Likely Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Acute Toxicity: Oral (rat) LD50 732 mg/kg; dermal (rabbit) LD50 >2000 mg/kg; inhalation (rat) LC50 4 hours estimate: 16 mg/L
Skin Corrosion/Irritation: Causes mild to moderate irritation
Eye Damage/Irritation: Causes moderate eye irritation
Respiratory/Skin Sensitization: No reliable data showing sensitizing effects
Carcinogenicity: No components classified as carcinogenic by IARC, NTP, OSHA
Other Effects: Prolonged or repeated contact may defat the skin; high vapor concentrations may cause neurological symptoms

Ecological Information

Toxicity to Aquatic Life: LC50 (96hr, fish): 18 mg/L, EC50 (48hr, daphnia): 13 mg/L
Persistence and Degradability: Moderate persistence in environment, slowly biodegradable
Bioaccumulative Potential: Moderate, based on log Kow value
Mobility in Soil: Low mobility due to low water solubility; may volatilize from soil and surface water
Other Adverse Effects: No evidence of significant long-term hazards, but harmful to aquatic organisms at elevated concentrations

Disposal Considerations

Waste Treatment Methods: Do not discharge to sewer system; dispose of material through licensed waste contractor
Contaminated Packaging: Empty containers must be thoroughly rinsed and sent to an approved facility; do not reuse packaging for food or drink
Disposal Precautions: Follow all municipal or state environmental regulations regarding chemical disposal; incinerate in an approved chemical incinerator

Transport Information

UN Number: UN 1992
UN Proper Shipping Name: Flammable liquid, toxic, n.o.s. (1,5-Dichloropentane)
Transport Hazard Class: 3 (flammable), 6.1 (toxic)
Packing Group: III
Environmental Hazards: Not classified as marine pollutant
Special Precautions: Secure tightly closed containers; transport in upright position; do not transport with foodstuff or animal feed

Regulatory Information

OSHA (US): Hazardous chemical as defined by OSHA Hazard Communication Standard
SARA Title III: Section 311/312 hazard categories: Immediate health hazard
TSCA: Listed on the US Toxic Substances Control Act inventory
REACH (EU): Registration required for importation into European Union; safety data available on ECHA portal
Other Regulations: Subject to workplace safety, labeling, and environmental protection regulations; consult national and local requirements for storage, handling, and use