MSDS for 1,4-Dibromobutane

Identification

Product Name: 1,4-Dibromobutane
Chemical Formula: C4H8Br2
Synonyms: Tetramethylene dibromide, 1,4-Butylene dibromide
CAS Number: 110-52-1
Recommended Use: Intermediate for organic synthesis, laboratory chemical
Restrictions on Use: Not intended for drug, food, or household use
Supplier: Supplier contact information and emergency phone number provided on request

Hazard Identification

GHS Classification: Acute Toxicity (Oral, Dermal, Inhalation), Skin Irritation, Eye Irritation
Signal Word: Danger
Hazard Statements: Harmful if swallowed, in contact with skin, or if inhaled; causes skin and eye irritation; may cause respiratory irritation
Pictograms: Exclamation mark, Health hazard
Precautionary Statements: Wear protective gloves, protective clothing, eye protection; wash hands thoroughly after handling; avoid breathing vapors or mist; use only outdoors or in a well-ventilated area
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Target Organs: Eyes, skin, respiratory system, gastrointestinal tract

Composition / Information on Ingredients

Chemical Identity: 1,4-Dibromobutane
Concentration: ≥ 98%
Impurities: May contain trace amounts of related halogenated butanes
Additives: None declared
Molecular Weight: 215.92 g/mol

First Aid Measures

Inhalation: Move affected person to fresh air; keep comfortable for breathing; seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing; wash skin thoroughly with soap and water; seek medical assistance if irritation develops
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and easy; continue rinsing; seek immediate medical attention
Ingestion: Rinse mouth; do not induce vomiting; seek medical advice immediately

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, alcohol-resistant foam
Unsuitable Extinguishing Media: Do not use water jet
Hazards from Combustion: Releases hydrogen bromide, carbon monoxide, carbon dioxide
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear
Special Precautions: Cool fire-exposed containers with water spray to prevent pressure buildup

Accidental Release Measures

Personal Precautions: Evacuate unnecessary personnel; avoid breathing vapors or mist; ensure adequate ventilation; use protective equipment
Environmental Precautions: Prevent entry into drains, sewers, or water bodies; notify authorities in event of significant spillage
Containment Methods: Stop leak if safe to do so; absorb spill with inert material (sand, earth, vermiculite)
Cleanup Procedures: Scoop up material and place into suitable, labeled waste container; decontaminate area with detergent and water; ventilate area after cleanup

Handling and Storage

Handling: Handle in a chemical fume hood; avoid contact with eyes, skin, and clothing; keep away from sources of ignition; avoid breathing vapors
Storage: Store in a tightly closed container, in a cool, dry, well-ventilated area; segregate from oxidizers, acids, and alkalis; keep away from direct sunlight and heat; store at recommended temperature stated by supplier
Hygiene Measures: Wash hands before eating, drinking, or using the restroom; remove contaminated clothing and wash before reuse

Exposure Controls and Personal Protection

Occupational Exposure Limits: Not established for 1,4-dibromobutane; keep exposures as low as reasonably achievable
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended limits
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), safety goggles or face shield, lab coat or chemical apron; use appropriate respiratory protection if ventilation is inadequate
Environmental Controls: Use containment to avoid environmental release; follow all relevant regulations regarding emissions

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Mild, sweetish
Odor Threshold: Not determined
pH: Not applicable
Melting Point: -5 °C
Boiling Point: 194-197 °C
Flash Point: 87 °C (closed cup)
Evaporation Rate: Not available
Flammability: Combustible under certain conditions
Explosive Limits: Not determined
Vapor Pressure: 0.55 mmHg at 25 °C
Vapor Density: 7.5 (air = 1)
Relative Density: 1.957 (water = 1)
Solubility: Insoluble in water; miscible with most organic solvents
Partition Coefficient (n-octanol/water): log Kow 2.4
Auto-ignition Temperature: Not available
Decomposition Temperature: Not established
Viscosity: Not available

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Possible Hazardous Reactions: May react with strong oxidizing agents, strong bases
Conditions to Avoid: Heat, flames, sparks, incompatible substances
Incompatible Materials: Strong oxidizers, strong alkalis, finely powdered metals
Hazardous Decomposition Products: Hydrogen bromide, carbon monoxide, carbon dioxide

Toxicological Information

Acute Toxicity: Oral LD50 (rat) ~445 mg/kg; Dermal LD50 (rabbit) > 2000 mg/kg; data show inhalation causes respiratory tract irritation
Skin Corrosion/Irritation: Irritates skin upon contact; prolonged exposure may cause dermatitis
Serious Eye Damage/Irritation: Causes irritation and potential corneal injury
Respiratory Sensitization: No data
Skin Sensitization: Not a known skin sensitizer
Germ Cell Mutagenicity: Limited data, not enough evidence for classification
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, or OSHA
Reproductive Toxicity: No specific data available
Specific Target Organ Toxicity-Single Exposure: May cause respiratory irritation, drowsiness, or dizziness
Specific Target Organ Toxicity-Repeated Exposure: Prolonged inhalation or contact may affect liver and kidneys in animal studies
Aspiration Hazard: Not classified

Ecological Information

Toxicity to Aquatic Life: Harmful to aquatic organisms; data for daphnia and fish indicate moderate acute toxicity
Persistence and Degradability: Slowly biodegradable in the environment; tends to persist in soil and sediment
Bioaccumulative Potential: May bioaccumulate in aquatic organisms; log Kow suggests potential for accumulation
Mobility in Soil: Low mobility in soil due to low water solubility
Other Adverse Effects: Avoid uncontrolled release to the environment

Disposal Considerations

Waste Treatment Methods: Incinerate in a chemical incinerator equipped with afterburner and scrubber, or dispose of in accordance with local, regional, or national regulations
Contaminated Packaging: Dispose of containers in accordance with official regulations; do not reuse empty containers
Special Precautions: Do not pour into drains, watercourses, or onto soil; keep chemicals apart from food and animal feed waste streams

Transport Information

UN Number: 2341
UN Proper Shipping Name: 1,4-Dibromobutane
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Marine Pollutant: Not classified, but harmful to aquatic life
Special Precautions for User: Follow DOT, IATA, and IMDG codes for transport; keep containers upright and sealed, away from incompatible goods
Hazard Label: Toxic

Regulatory Information

Safety, Health, and Environmental Regulations: Subject to TSCA in the United States; listed under EINECS/ELINCS for Europe
SARA Title III Sections 302/304: Not listed
SARA Title III Section 313: Not subject
California Proposition 65: Not listed
International Inventories: Listed in major chemical inventories (TSCA, EINECS, DSL, etc.)
Other Regulations: Work according to all local, national, and international regulations for handling hazardous materials