Material Safety Data Sheet: 1,4-Dibromobenzene

Identification

Product Name: 1,4-Dibromobenzene
Chemical Formula: C6H4Br2
Synonyms: p-Dibromobenzene, Para-dibromobenzene
CAS Number: 106-37-6
Recommended Use: Laboratory reagent, intermediate in organic synthesis
Supplier Details: Name and address should be verified for each shipment
Emergency Contact: Phone numbers accessible from local distributor
UN Number: 2723
EC Number: 203-397-0

Hazard Identification

GHS Classification: Acute Toxicity (Oral, Dermal, Inhalation) - Category 4; Eye Irritation - Category 2B; Aquatic Acute - Category 2
Signal Word: Warning
Hazard Statements: Harmful if swallowed, inhaled, or in contact with skin. Causes eye irritation. Toxic to aquatic life.
Pictograms: Exclamation mark, environment
Precautionary Statements: Avoid release to the environment. Wear protective gloves and eye protection. Wash thoroughly after handling. Do not eat, drink or smoke while using.
Other Hazards: May form harmful dust and vapors during handling.

Composition / Information on Ingredients

Chemical Name: 1,4-Dibromobenzene
Synonyms: Para-dibromobenzene
CAS Number: 106-37-6
Concentration: ≥99% by weight
Impurities: Minimal; no other constituents contributing to classification as hazardous
Molecular Weight: 235.91 g/mol

First Aid Measures

Inhalation: Remove person to fresh air. Keep comfortable for breathing. Seek medical attention if symptoms develop.
Skin Contact: Remove contaminated clothing. Rinse skin with plenty of water and mild soap. Seek medical advice if irritation develops.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Consult an eye specialist if irritation persists.
Ingestion: Rinse mouth thoroughly. Do not induce vomiting. Get medical attention if uneasy or if large amounts have been swallowed.
Symptoms: May cause nausea, dizziness, sore throat, coughing, skin and eye irritation.

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray
Unsuitable Extinguishing Media: Direct water stream may spread material
Specific Hazards: Combustion produces toxic fumes such as carbon monoxide, carbon dioxide, hydrogen bromide
Protective Equipment: Self-contained breathing apparatus, full protective clothing
Advice for Firefighters: Prevent contaminated water runoff. Cool closed containers exposed to fire with water.
Special Procedures: Fight fire from a safe distance due to risk of explosion with high heat.

Accidental Release Measures

Personal Precautions: Avoid breathing dust or vapors. Use adequate ventilation. Wear protective gloves, clothing, and eye/face protection.
Environmental Precautions: Prevent material from entering drains, waterways, and soil.
Cleanup Methods: Sweep up and place in suitable container for disposal. Avoid generating dust. Clean area thoroughly with water and detergent.
Emergency Procedures: Evacuate unprotected personnel. Inform responsible authorities in the event of environmental contamination.

Handling and Storage

Handling: Avoid contact with skin, eyes, and clothing. Avoid inhalation of dust or vapor. Wash hands thoroughly after handling. Handle in accordance with good industrial hygiene.
Storage Conditions: Store in tightly closed container in a cool, dry, well-ventilated area. Protect from light, moisture, and incompatible substances.
Incompatible Materials: Strong oxidizing agents, strong bases, metals
Special Requirements: Store away from food and drink. Keep out of reach of children and unauthorized personnel.

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific occupational exposure limits established
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended limits
Personal Protective Equipment: Chemical-resistant gloves, safety goggles or face shield, protective clothing, and appropriate respiratory protection for dust
Hygiene Measures: Do not eat, drink, or smoke during use. Wash hands and face after handling. Remove contaminated clothing and wash before reuse.
Environmental Controls: Prevent material from reaching public sewage or natural water sources.

Physical and Chemical Properties

Appearance: White to off-white crystalline solid
Odor: Faint aromatic odor
Odor Threshold: Not available
pH: Not applicable
Melting Point/Freezing Point: 86-88°C
Boiling Point: 220°C
Flash Point: 132°C (closed cup)
Evaporation Rate: Not available
Flammability: Combustible
Vapor Pressure: 0.18 mmHg at 25°C
Vapor Density: 8.1 (air = 1)
Relative Density: 1.95 g/cm³
Solubility: Insoluble in water; soluble in ether, alcohol, benzene
Partition Coefficient (n-octanol/water): log Kow: 4.76
Auto-ignition Temperature: 540°C
Decomposition Temperature: Not determined
Viscosity: Not applicable

Stability and Reactivity

Chemical Stability: Stable under normal ambient and anticipated storage conditions
Possibility of Hazardous Reactions: None under normal conditions; may react with strong oxidizing agents
Conditions to Avoid: Excess heat, incompatible materials, open flame, static discharge
Incompatible Materials: Strong acids, bases, and oxidizers
Hazardous Decomposition Products: Carbon oxides, hydrogen bromide, bromine fumes

Toxicological Information

Acute Toxicity: Harmful if swallowed, inhaled, or in contact with skin
Routes of Exposure: Inhalation, ingestion, dermal, ocular
Symptoms: Nausea, dizziness, irritation of mucous membranes, coughing
Skin Corrosion/Irritation: May cause mild irritation
Serious Eye Damage/Irritation: May cause mild eye irritation
Respiratory or Skin Sensitization: Not expected to cause sensitization
Germ Cell Mutagenicity: Not classified as mutagenic
Carcinogenicity: Not listed by IARC, NTP, OSHA
Reproductive Toxicity: Data insufficient for classification
STOT-single exposure: May cause respiratory irritation
STOT-repeated exposure: No significant data
Aspiration hazard: Not classified as an aspiration hazard

Ecological Information

Ecotoxicity: Toxic to aquatic organisms; may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Not readily biodegradable
Bioaccumulative Potential: Potential for bioaccumulation in aquatic life
Mobility in Soil: Limited; likely to partition to sediments
Other Adverse Effects: May pose hazard to aquatic ecosystems due to persistence and accumulation

Disposal Considerations

Waste Treatment Methods: Dispose of product and container in accordance with local, regional, and national regulations
Disposal Recommendations: Incinerate in approved facility or landfill as hazardous waste based on local laws
Unused Product: Consult waste management authorities about appropriate disposal
Contaminated Packaging: Triple rinse containers before reuse or disposal. Dispose of rinsate as hazardous waste. Do not reuse emptied containers for other purposes.

Transport Information

UN Number: 2723
Proper Shipping Name: 1,4-Dibromobenzene
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Marine Pollutant: Yes
Label Required: Toxic (skull and crossbones), Environment
Special Precautions for User: Avoid release to the environment. Transport in secure, labeled containers.

Regulatory Information

TSCA Status: Listed
EU REACH Status: Regulated; refer to ECHA database
Canada (DSL): Listed
Hazard Category (CERCLA/SARA): Not classified as extremely hazardous
WHMIS Classification: D2B (Toxic Material Causing Other Toxic Effects)
California Prop 65: Not listed
Other National Inventories: Check local regulations for additional reporting and labelling requirements