1,4-Dibromobenzene: A Closer Look at an Underappreciated Chemical
Historical Development
Nobody can talk about 1,4-dibromobenzene without glancing back at the days when chemists stumbled upon ways to modify simple benzene rings. Leopold Gmelin’s early 19th-century work on halogenated aromatics paved the way for more targeted bromination efforts. The drive came from industrial needs—dyes, early photographic chemicals, and flame retardants. Industry scouts quickly learned that two bromines at the para position would open up a batch of new options for synthesis, leading to the routine manufacture of this compound in labs around Europe and North America by the late 1800s. Modern advances pushed purity higher and focused production routes, but this molecule always drew eyes for its blend of stability and reactivity.
Product Overview
You’ll find 1,4-dibromobenzene as a white crystalline solid. Its formula, C6H4Br2, puts two bromine atoms opposite each other on benzene’s six-carbon ring. Most labs and factories keep it in tin-lined steel drums, away from sunlight or high temperatures. Companies supply it under names such as para-dibromobenzene, p-dibromobenzene, and occasionally p-bromobenzene. These synonyms surface across Material Safety Data Sheets and procurement documents. This substance shows off useful melting and boiling points that set it apart from similar compounds, making it attractive for several industrial recipes.
Physical & Chemical Properties
Solid at room temperature, 1,4-dibromobenzene forms colorless to white plates or crystals. You’ll catch a faint, sometimes sweet aromatic odor when working with it. The melting point hovers near 87°C, while it boils at about 220°C. Its density crosses 1.9 g/cm³—heavier than water by a mile, thanks to the bulky bromines hugging the ring. Insoluble in water but blending well with organic solvents like acetone or chloroform, it fits right into organic synthesis protocols. Thermal and chemical stability dominates unless strong nucleophiles or lengthy UV exposure enter the picture.
Technical Specifications & Labeling
Lab shipments of 1,4-dibromobenzene list content purity, usually above 98% for synthetic and analytical uses. Labels flag the substance’s CAS number (106-37-6) and common risk codes. Regulations require clear hazard pictograms—flame signal words for irritant properties, environmental warnings tied to aquatic toxicity, batch numbers, and manufacturing dates for traceability. Data sheets often report trace levels of monochlorinated and tribromo impurities, essential for applications demanding precise reaction yields or low halogen content. The product’s lot analysis, available for audit, helps users select the right grade depending on downstream use.
Preparation Method
Years ago, most chemists reached for direct bromination: mix benzene with bromine and a Lewis acid like iron(III) bromide to guide the reaction. Controlling temperature and bromine equivalents favored the para isomer over ortho or meta versions. Today, multi-ton production follows similar routes but with improved selectivity. Some routes handle monochlorobenzene or p-dichlorobenzene as intermediates, swapping chlorines for bromines in nucleophilic aromatic substitution. While safer and more efficient, production still requires responsible handling of bromine gas—a notorious irritant and environmental burden. Many plants recycle waste streams to limit exposure and emissions, a lesson learned from early gaffes with halogen handling.
Chemical Reactions & Modifications
Chemists value 1,4-dibromobenzene for its versatility. The bromine atoms serve as excellent leaving groups, letting synthetic teams swap them for a host of other atoms. Suzuki and Heck coupling reactions, modern pillars in drug and material manufacture, use this substrate to stitch unique carbon frameworks. You’ll see it feed polymers and specialty dyes through functionalization at both bromine sites. Reductive removal of bromines or further halogenation pushes it into dyes, flame retardants, liquid crystals, and other performance chemicals. In undergraduate chemistry labs, it forms part of practicals on electrophilic aromatic substitution, offering good yield and easy product recovery.
Synonyms & Product Names
Rack up the synonyms: para-dibromobenzene, p-dibromobenzene, 1,4-dibromobenzol, or even just “dibromobenzene” if context allows. Chemical wholesalers and safety professionals rely on the official name—1,4-dibromobenzene—to avoid confusion with its ortho and meta cousins, which show different reactivity and hazards. In research, common shorthand “p-DBB” pops up, especially in discussion of advanced coupling chemistry or polymer formation.
Safety & Operational Standards
Handling 1,4-dibromobenzene calls for vigilance. It irritates the eyes, skin, and respiratory tract. Once airborne as dust or vapor, it poses risks through inhalation, especially with repeated exposure. OSHA and EU REACH guidelines stress gloves, goggles, closed vessels, and fume hood work—no shortcuts for students or professionals. Spilled solid should be swept up with minimal dust raised, and sites must have chemical-specific spill kits. Environmental rules bar disposal down drains, redirecting waste into solvent waste bins or incineration. Training drills help workers handle splits and accidental exposures without delay. Manufacturers keep data on exposure incidents and root cause analysis to tighten protocols and improve emergency response plans.
Application Area
Industrial routines plug 1,4-dibromobenzene into flame retardant manufacture, essential for plastics in electronics and building materials. Dye makers grab it to generate rich hues for textiles. Specialty polymers rely on its dibromo structure as a building block for resins and conductive materials. Some labs use it in pest control, but that practice has waned due to tighter regulations on halogenated organics. It pops up in academic research—chemical education leans on its clarity and manageable hazards during teaching experiments. Its role in liquid crystal research for display screens now draws interest as manufacturers seek alternatives to traditional molecules for higher-performing screens.
Research & Development
Over the past two decades, academic and industrial labs have dug, prodded, and teased apart new uses for 1,4-dibromobenzene. Synthetic teams continue to push palladium and nickel catalyst systems for easier carbon–carbon bond-forming reactions. Material scientists look for better flame retardancy with less environmental persistence, using dibromo units in recyclable or biodegradable smart plastics. Digitized chemical libraries help teams map its reactivity, churning out candidate molecules for medicinal and agrochemical screens. Significant grants fund work to engineer greener bromination methods and safer extraction or purification, realizing both industry and regulators demand lower-waste and safer alternatives.
Toxicity Research
Older studies flagged skin and eye irritation in rodent and cell models when dosed with solid or vapor 1,4-dibromobenzene. Evidence links bioaccumulation in aquatic organisms to chronic toxicity, pressing for strict limits on water release from industrial sites. Epidemiology on long-term human harm stays thin, but expert panels warn against chronic, low-dose exposure in manufacturing. Encouraging recent work tracks metabolic breakdown, revealing rapid glucuronidation and elimination in mammals, but flags concerns if overwhelmed by high or repeated exposure. Regulatory reviews, particularly in the EU, continue to feed new safety thresholds and environmental release policies.
Future Prospects
1,4-Dibromobenzene has more than once shown up in talks about the future of chemical manufacturing. Researchers in sustainable chemistry design organic reactions to work under milder, solvent-free conditions, and 1,4-dibromobenzene gets slotted as a stable halide for experimentation. Efforts line up to lower hazardous waste, boosting catalyst recovery and recycling wherever possible. As flame retardancy requirements outpace legacy additives, chemists eye new structures with better performance and less environmental damage—dibromo aromatics stand as promising alternatives. Regulation always plays catch-up, but focused innovation keeps demand alive. Young researchers experiment with this molecule’s reactivity for new pharmaceuticals and functional polymers. The stakes rise every year: safer workplaces, greener factories, cleverer materials, and all roads pass through molecules like 1,4-dibromobenzene.
A Closer Look at 1,4-Dibromobenzene
1,4-Dibromobenzene catches the attention of more than just chemists. Most folks don’t run into it at the grocery store, but it plays a real role behind the scenes in many industries. Folks know it as a chemical compound with two bromine atoms attached to a benzene ring, and its uses turn up in a handful of practical places.
Everyday Uses Rooted in Chemistry
Manufacturers lean on 1,4-dibromobenzene for its staying power as an intermediate in chemical production. This compound seems simple, but it acts as a building block for making more complex molecules. Speaking from a background in material science, I’ve seen how intermediates like 1,4-dibromobenzene trim down production delays and lower waste in industrial settings. For example, chemical plants combine it with other substances to create active pharmaceutical ingredients and agricultural chemicals. Pairing reliability with predictability in reactions helps keep costs in check and products steady.
Dye makers also find value here. They count on this compound for certain coloring agents. You might not think about where your colored clothing or household items get their hues, but 1,4-dibromobenzene helps provide those bold and stable shades. It basically strengthens certain dyes, keeping colors fresh longer and making fading far less common. The long-lasting color in fabrics or plastics owes something to the steady chemistry of dibromobenzene.
Specialty Polymers and Electronics
Growing up near a small electronics shop, I watched technicians work with printed circuit boards all the time. What I didn’t realize as a kid is that 1,4-dibromobenzene feeds into the production of specialty polymers. Modern electronics often demand plastics that resist heat and wear, which don’t just materialize from thin air. Dibromobenzene serves as a key ingredient in crafting some of these advanced plastics. It brings flame-retardant properties, which cut down the risk of short circuits and fires in everyday gadgets. The stability of circuit boards and cables draws directly from compounds like this one.
Concerns from Experience and Health Studies
Plenty of people voice concerns about chemical compounds like dibromobenzene making their way into the environment and affecting health. Studies note that extended exposure may cause irritation or other health risks, especially for those working directly with it in industrial settings. I’ve spoken with workers at chemical plants who stress the importance of training, access to protective equipment, and restorative break routines. They point out that slick labeling and up-to-date safety protocols matter for everyone on the floor.
Researchers check for impacts on air and water quality too, since harmful molecules tend to travel farther than we expect. Particularly in the era of public awareness about pollution, communities want more transparency about what flows into their air and soil. Regulators in most developed places push manufacturers toward regular safety audits and waste treatment improvements for substances like dibromobenzene.
Responsible Use and Solutions
The story of 1,4-dibromobenzene shows how progress depends on responsible practices. Switching over to greener solvents, adding real-time sensors to monitor exposure, and boosting worker education will make a difference. I saw one company reduce their emissions by bringing in closed-loop systems—these setups recycle chemicals and slash both waste and costs. Being transparent about sourcing and handling processes reassures both consumers and neighboring communities. As a matter of trust and safety, companies do best when they operate above-board and embrace new technology that protects people and places.
1,4-Dibromobenzene plays an important role in modern products, but its future likely depends on a commitment to safety and thoughtful stewardship.
Understanding the Risks of 1,4-Dibromobenzene
1,4-Dibromobenzene shows up in lab settings and sometimes in industrial workplaces. Folks handling this substance deal with an aromatic compound that brings some health challenges. Even a small spill or a bit of dust can set off skin or eye irritation. If someone breathes in vapor or dust, headaches, nausea, or throat problems can follow. People who have worked with this stuff often keep safety rules front and center for good reason.
Personal Protective Equipment Isn’t Optional
Anyone who uses 1,4-dibromobenzene starts with gloves—nitrile or some thick chemical-resistant style does the trick. I’ve seen coworkers get careless with thin gloves and regret it when skin irritation kicks in. Splash-proof goggles shield your eyes from sneaky droplets. A well-fitted lab coat means less chance of stains on street clothes or skin. Closed shoes, not sandals, should always cover feet.
If there’s a chance of dust or fumes, a respirator fitted for organic vapors adds another protection layer. No one enjoys wearing it, but folks who try to skip the mask end up with headaches from vapor exposure. In spaces where air flow drops or the risk of a spill runs high, masks aren’t up for debate.
Work in a Well-Ventilated Area
Fume hoods are more than fancy boxes—they are your first shield against breathing nastiness. Work with 1,4-dibromobenzene inside a hood, not out on an open bench. In stuffy rooms, vapors build up fast. A decent exhaust system or fan pulls fumes outside. Anyone who thinks a window alone can clear the air should watch how quickly fumes collect around an open dish. A colleague once thought a simple fan was enough, but the smell lingered, and so did the cough.
Handling, Storage, and Spills: No Room for Shortcuts
Pour from small containers, don’t free-hand from jugs. Use labeled bottles. Keep containers sealed tight and stored in a dry, cool spot—far from heat or open flames. The chemical doesn’t play well with oxidizers or metal powders, so avoid stacking it near those materials. Lock-up cabinets with a spill tray underneath boss even minor leaks.
Spills call for quick thinking. Soak it up with an absorbent pad, sweep it into a labeled bag, wash the surface well. No vacuum cleaners—those spread the problem instead of fixing it. Anyone who’s swept up a powder spill without gloves remembers the rash that follows. In case a big dose lands on clothing or skin, water and soap come before worry; rinse the spill right out.
Waste Disposal and Training
Local environmental rules say how to throw away waste. Pouring leftovers down the sink only creates bigger troubles—a habit that’s led to fines and environmental issues before. Chemical waste bins keep the workplace and neighbors safe. Inside the lab, regular training updates usually make people roll their eyes, but nothing spells trouble like new staff skipping safety steps. Refresher courses keep old hands sharp and new hires aware.
Caring for Your Crew and Yourself
Safety doesn’t exist on paper. If someone feels dizzy or itchy, reporting it saves time and health. Eye washes and showers should sit close by, not hidden in storage closets—every second counts during an emergency. Everyone has stories about missed safety lessons or forgotten equipment, which show scars or lasting coughs as reminders. Looking out for each other keeps the next mishap from happening.
Trust in Rules and Experience
Lab safety sounds boring until a careless move puts someone in an ER. From labeling bottles to emptying chemical waste bins, every step has shaped by problems faced before. Each guideline comes from real people and real slip-ups. Take them seriously. The right gear and good habits turn a risky task into a smooth routine, and everyone goes home healthy.
The Chemical Formula and What It Means
1,4-Dibromobenzene shows up in textbooks as C6H4Br2. To break that down, the molecule contains six carbon atoms, four hydrogens, and two bromine atoms. It takes the benzene ring—a six-membered carbon ring most people encounter in basic chemistry—and swaps two of the original hydrogens for bromine atoms. Those bromines land opposite each other, at the 1 and 4 positions.
Distinct Structure: Not Just a Science Class Example
Chemists often sketch this molecule as a regular hexagon (the benzene ring), each corner a carbon, with alternating single and double lines inside to represent the delocalized electrons. Add bromine atoms to carbon 1 and carbon 4 on that ring, with the other four corners holding hydrogen atoms. This arrangement gives 1,4-Dibromobenzene its name and unique properties. The two bromine atoms directly across from each other influence how the compound interacts with others. For anyone who’s struggled with aromatic chemistry, visualizing these positions can make a complicated field much less intimidating.
Why the Details Matter: Everyday Impacts of a Basic Compound
Ask anyone working in materials science, and they’ll tell you the little changes—like where a bromine atom lands on a benzene ring—can make or break a whole process. I once worked with a team synthesizing polymers, where using 1,4-Dibromobenzene as a starting material sped up a synthesis route by days. In that case, the visibility of the chemical structure and exact placement of each atom allowed for precise reactions that led to materials with predictable properties. Without that control, results can turn unpredictable or even dangerous.
The same chemical appears in the production of certain dyes and pharmaceuticals. Its clear structure helps scientists build more complex molecules, keeping the process reliable. Fields such as organic electronics lean on the reliability of molecules like 1,4-Dibromobenzene for making organic light-emitting diodes (OLEDs) and similar technologies. People might overlook these molecules, but they stand at the center of real, touchable advances.
Health and Environmental Considerations
It’s not only chemists who care about the nitty-gritty of such chemicals. Despite its usefulness, 1,4-Dibromobenzene carries risks typical of many synthetic organic compounds. The molecule reveals its darker side in toxicity and persistence. Brominated compounds resist breaking down naturally, sticking around in soils and water. Respiratory and skin irritation can show up quickly with exposure, so proper handling turns into a must. Simple fume hoods and protective gloves make a huge difference.
In my experience visiting both academic labs and industrial plants, effective training in chemical safety often hinges on understanding the exact molecules involved. If workers see the exact structure—knowing that two heavy bromines ride on a benzene ring—it seems to click better than simply listing chemical names on a hazard sheet. Discussion of real risks helps move safety from theory to daily practice.
Advancing Safe and Smart Use
Solutions for safer use go beyond regulation. Good labeling, accessible education, and modern engineering controls keep exposure low and environmental impacts minimal. Substituting less persistent or less toxic chemicals where possible reduces the burden. Green chemistry aims for this goal, though sometimes industry still returns to proven compounds like 1,4-Dibromobenzene for specific reasons.
Understanding the structure and formula of 1,4-Dibromobenzene shapes how we use it, work with it safely, and look for better alternatives in the future. It’s never just about the atoms; it’s about what those atoms let us do—and how responsibly we handle the privilege.
Understanding the Chemical Up Close
1,4-Dibromobenzene doesn’t ever pop up in everyday conversation, but for people who work in science labs or industries dealing with organic chemistry, it has a real and direct impact. This compound—used in research, dyes, and sometimes pesticides—brings with it more than technical jargon. It’s a crystalline solid with a strong odor, easy enough to spot, but packed with potential hazards for both humans and the environment. Forgetting about proper storage can turn a routine job into an emergency.
The Real-World Hazards
One misstep with 1,4-dibromobenzene, and the results don’t just affect a small corner of a storeroom. It’s flammable, volatile, and can irritate your skin, eyes, and respiratory tract. The EPA flags its toxicity and risk to aquatic life, which means spills go far beyond personal inconvenience—they threaten water supplies and wildlife. I’ve seen the aftermath of neglected chemicals firsthand: sudden evacuations, expensive cleanup, and, worst of all, injuries that could have been prevented.
Temperature and Containment
Dusty, overheated storerooms don’t mix well with this compound. Consistent, cool temperatures make the difference between a stable powder and an accidental chemical cloud. People think “room temperature” is safe, but rooms heat up, especially in summer months or with poor ventilation. I always go for climate control around organics like these—air conditioning, shaded areas, never near heaters or direct sunlight. A tight, sealed, labeled container stops both evaporation and contamination. Cheap, generic bins might seem tempting, but shatterproof glass or high-grade polyethylene withstand the chemical’s bite far better.
Avoiding Cross-Contamination
I’ve watched chemicals get stored on the same shelf, leading to mystery leaks, unpredictable reactions, or so much more paperwork than anyone wants. For 1,4-dibromobenzene, isolation is as much about chemistry as it is about peace of mind. Keep acids, oxidizers, bases, and even food or drinks away—a sealed, clearly labeled shelf cuts down on mistakes. Spill containment trays become non-negotiable, especially in any place where floor drains hide below shelving. These trays catch accidental leaks before they turn into full-scale spills that require emergency response.
Good Record Keeping
Labels that fade or peel off aren’t just inconvenient; they’re dangerous. Permanent markers, waterproof tape, printed hazard symbols—they all pay for themselves over time. I log every transfer or use in a simple spreadsheet, and others do the same. It helps track aging stock and prevents the “mystery bottle” phenomenon that worries even seasoned chemists. This record keeping isn’t about bureaucracy as much as about safety and quick response in case something leaks or goes missing.
Personal Protective Equipment
Nitrile gloves, goggles, and lab coats might look like overkill to anyone outside the field, but even small skin exposure can bring on irritation or worse. It’s not paranoia; it’s practicing the kind of caution that keeps accidents from turning severe. Ventilated storage cabinets equipped with fume extraction give extra insurance against vapor buildup. No one likes the smell of 1,4-dibromobenzene lingering after a bottle’s been opened, and mitigating exposure is good sense—both for the body and the mind.
Training and Oversight
Accidents usually trace back to gaps in training. Sharing stories, reviewing incident reports, and running practice drills all help keep safety from feeling like a box to check. Bringing new staff up to speed, not just on procedures but the “why” behind them, builds habits that save time and lives. I’ve seen teams grow more confident and vigilant with even short refreshers or walk-throughs of the storage area.
Keeping Eyes Open
Good storage goes beyond ticking items off a checklist. It’s a habit of caution, a culture where people watch out for each other. It only takes one slip for a chemical like 1,4-dibromobenzene to cause trouble, and a few simple habits—climate control, strict labeling, isolation, prompt cleanup, and attentive training—shape safer workspaces. It’s always worth that little extra effort.
Everyday Exposure: Less Common, Not Less Risky
I remember in my college chemistry class, the lab lockers always carried a whiff of strange smells. One day the topic turned to halogenated benzenes—heavy-sounding chemicals most folks never meet outside a textbook. 1,4-Dibromobenzene falls right into that group. Used in organic synthesis, it's part of some dyes and pesticides. You don't pick up a bottle of it at the store, but its presence in specialty manufacturing means it touches more of our surroundings than people realize.
Touch and Inhale: Not Your Usual Allergy Risk
Some chemicals you can touch, smell, and pay no price. 1,4-Dibromobenzene doesn't fit the bill. Research published by the National Library of Medicine highlights that direct skin exposure can cause irritation and possibly burns. It vaporizes faster than you expect at room temperature, and inhalation brings its own troubles—headaches, dizziness, and nausea start to show up before the industrial-strength scent pushes you from the room.
Workers in plants producing this compound often face higher exposure. Studies from the CDC note that these folks report more headaches, eye problems, and even longer-term issues with repeated exposure. Handling needs more than cheap gloves and open windows. I’ve talked to lab technicians who insist on goggles, face shields, and real ventilation—even if it means steamy safety glasses in a hot room.
Not Friendly to Fish and Soil
Chemicals like 1,4-Dibromobenzene rarely stay put. Once spilled or dumped, they seep into soil and waterways. From experience growing up near an industrial site, I saw how even “trace contaminants” can add up. EPA testing shows this compound sticks around in the environment for months. Fish and small aquatic creatures start dying off when levels climb—long before it harms bigger animals, creating a break in the chain of life below the water.
There’s also a risk for crops; uptake through roots can lead to gradual buildup in edible plants. If runoff trickles into garden soils, folks eating homegrown veggies may face low but steady exposure. Not all risks appear right away. Chronic toxicity sometimes takes years to show, and that's a problem families and farmers in affected zones know all too well.
Environmental Regulations: Hard Rules, Patchy Practice
Governments like the U.S. and EU have clear guidelines for industrial use and waste disposal of brominated benzenes. Real-world enforcement drags behind policy, though. I’ve argued with managers reluctant to spring for safer waste treatments, and the economics often determine just how careful companies act. Cost-cutting pushes risky shortcuts, especially where oversight runs thin.
Safer Choices: People and Policy
Pressing for substitute chemicals with lower risk marks progress. In places where 1,4-Dibromobenzene remains essential, workers and communities speak up for better handling, storage, and cleanup measures. Advocacy works—local groups near manufacturing plants have driven policy updates, forcing better filtration and emergency response plans.
More can happen. Public access to chemical inventory and spill records pushes companies to step up. Ongoing research leads to less toxic alternatives and smarter engineering controls. Education—whether in the workplace or the classroom—helps everyone make choices that put health and the environment before convenience.


| Names | |
| Preferred IUPAC name | 1,4-dibromobenzene |
| Other names |
para-Dibromobenzene
p-Dibromobenzene p-Bromobromobenzene |
| Pronunciation | /waɪ.t̬əˌdaɪˌbroʊ.moʊˈbɛn.ziːn/ |
| Identifiers | |
| CAS Number | 106-37-6 |
| Beilstein Reference | 1208738 |
| ChEBI | CHEBI:34694 |
| ChEMBL | CHEMBL135896 |
| ChemSpider | 10715 |
| DrugBank | DB06712 |
| ECHA InfoCard | 03b02baf-1b76-4a9c-8d65-1c55f3c9be64 |
| EC Number | 201-540-4 |
| Gmelin Reference | Gmelin 116206 |
| KEGG | C08398 |
| MeSH | D003971 |
| PubChem CID | 7236 |
| RTECS number | CZ9625000 |
| UNII | 0996C6Y1EZ |
| UN number | UN2516 |
| CompTox Dashboard (EPA) | 'DTXSID8020512' |
| Properties | |
| Chemical formula | C6H4Br2 |
| Molar mass | 235.90 g/mol |
| Appearance | White crystalline solid |
| Odor | penetrating aromatic odor |
| Density | 1.50 g/cm³ |
| Solubility in water | slightly soluble |
| log P | 3.86 |
| Vapor pressure | 0.004 mmHg (25°C) |
| Acidity (pKa) | 31.0 |
| Magnetic susceptibility (χ) | -75.0×10⁻⁶ cm³/mol |
| Refractive index (nD) | 1.613 |
| Viscosity | 1.779 mPa·s (at 25 °C) |
| Dipole moment | 1.262 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 129.3 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | 45.9 kJ/mol |
| Std enthalpy of combustion (ΔcH⦵298) | -3235.8 kJ/mol |
| Hazards | |
| Main hazards | Harmful if swallowed, causes skin irritation, causes serious eye irritation. |
| GHS labelling | GHS02, GHS07 |
| Pictograms | GHS07 |
| Signal word | Warning |
| Hazard statements | H302, H315, H319, H411 |
| Precautionary statements | P261, P264, P270, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P362+P364, P403+P233, P405, P501 |
| NFPA 704 (fire diamond) | 1-2-0 |
| Flash point | 113 °C |
| Autoignition temperature | 540 °C |
| Lethal dose or concentration | LD50 (oral, rat): 2,695 mg/kg |
| LD50 (median dose) | LD50 (median dose): 2000 mg/kg (oral, rat) |
| NIOSH | SN 1220000 |
| PEL (Permissible) | Not established |
| REL (Recommended) | 0.1 ppm |
| IDLH (Immediate danger) | 50 ppm |
| Related compounds | |
| Related compounds |
Bromobenzene
1,2-Dibromobenzene 1,3-Dibromobenzene Chlorobenzene 1,4-Dichlorobenzene 1,4-Diiodobenzene |