1,3-Dibromopropane MSDS Information

Identification

Product Name: 1,3-Dibromopropane
Chemical Formula: C3H6Br2
CAS Number: 109-64-8
Synonyms: Trimethylene dibromide
Recommended Use: Laboratory chemical, used in organic synthesis
Manufacturer: Refer to supplier label for contact information
Emergency Phone Number: Refer to local supplier details

Hazard Identification

GHS Classification: Acute Toxicity (Oral & Inhalation), Eye Irritation, Skin Irritation
Signal Word: Danger
Hazard Statements: Toxic if swallowed, causes skin and eye irritation, harmful if inhaled
Pictograms: Skull and crossbones, exclamation mark
Precautions: Avoid breathing vapors, prevent contact with skin and eyes, wash thoroughly after handling, keep container tightly closed
Hazards Not Otherwise Classified: May behave as a narcotic at high concentrations

Composition / Information on Ingredients

Chemical Identity: 1,3-Dibromopropane
Concentration: >99%
Impurities: Trace organics may occur
Molecular Weight: 201.89 g/mol

First Aid Measures

Inhalation: Move to fresh air, get medical attention if symptoms develop, provide respirations if breathing stops
Skin Contact: Remove contaminated clothing, immediately flush skin with plenty of water for at least 15 minutes, seek medical help
Eye Contact: Rinse thoroughly with water for 15 minutes, hold eyelids open, get medical attention
Ingestion: Do not induce vomiting, rinse mouth with water, never give anything by mouth to an unconscious person, seek immediate medical aid
Major Symptoms: Irritation to mucosa, dizziness, headache, nausea
Note To Physician: Treat symptomatically and provide supportive care

Fire-Fighting Measures

Flammability: Not highly flammable but can burn under strong ignition
Extinguishing Media: Use carbon dioxide, dry chemical powder, water spray, alcohol-resistant foam
Special Hazards: Produces toxic fumes of hydrogen bromide and carbon oxides in fire
Protective Equipment: Wear self-contained breathing apparatus, full protective clothing
Advice For Firefighters: Cool containers with water spray, avoid inhaling vapors, evacuate area if necessary

Accidental Release Measures

Personal Precautions: Wear appropriate protective equipment, ventilate area well, keep away from ignition sources
Environmental Precautions: Prevent further leakage or spillage if safe, do not let product enter drains or watercourses
Emergency Procedures: Evacuate area, isolate hazard
Methods For Clean-up: Absorb with inert material (sand, earth, vermiculite), collect in closed containers for disposal, wash spill site after pickup

Handling and Storage

Safe Handling: Use in a well-ventilated area, avoid contact with eyes, skin, and clothing, avoid inhaling vapors
Hygiene Practices: Wash hands after handling, remove contaminated clothing and wash before reuse
Storage Conditions: Store in a tightly closed container in a cool, dry, well-ventilated location, keep away from incompatible materials such as strong bases and oxidizers
Storage Temperature: Keep below 25°C, avoid direct sunlight

Exposure Controls and Personal Protection

Engineering Controls: Use local exhaust ventilation to maintain vapor concentrations below occupational limits
Personal Protection: Chemical-resistant gloves (nitrile, neoprene), safety goggles or face shield, laboratory coat, respiratory protection if exposure limits are exceeded
Exposure Limits: No ACGIH TLV or OSHA PEL established
Environmental Exposure Control: Prevent leakages and routine releases into sewers or water systems

Physical and Chemical Properties

Appearance: Clear, colorless to pale yellow liquid
Odor: Penetrating, similar to bromine compounds
Boiling Point: 196 - 198°C
Melting Point: -37°C
Flash Point: 88°C (closed cup)
Explosive Limits: Not determined
Vapor Pressure: 0.38 mmHg @ 25°C
Vapor Density: 7 (Air = 1)
Solubility: Practically insoluble in water, miscible with organic solvents
Density: 2.17 g/cm³ @ 20°C
Partition Coefficient: log Kow: 2.2
pH: Not applicable

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling conditions
Hazardous Reactions: Reacts violently with strong bases, oxidizers
Polymerization: Will not occur
Conditions To Avoid: Heat, flames, moisture, incompatible materials
Decomposition Products: Hydrogen bromide, carbon oxides

Toxicological Information

Acute Toxicity: LD50 (oral, rat): 161 mg/kg
Inhalation Effects: May cause respiratory tract irritation, drowsiness, headache
Skin Corrosion/Irritation: Causes irritation and possibly burns
Eye Damage/Irritation: Causes severe irritation
Chronic Effects: May damage internal organs on prolonged exposure, risk of central nervous system effects
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Reproductive Toxicity: Data not sufficient, animal tests indicate possible effects
Sensitization: Not reported

Ecological Information

Toxicity: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Persistence/Degradability: Not rapidly biodegradable, persistent in water and soil
Bioaccumulation: Moderate potential (based on log Kow)
Mobility in Soil: Expected low due to low water solubility
Other Adverse Effects: Avoid uncontrolled releases to the environment

Disposal Considerations

Waste Disposal Method: Dispose of in accordance with local, regional, and national regulations, use a licensed chemical waste contractor
Contaminated Packaging: Containers must be triply rinsed and then destroyed or sent for controlled incineration
Special Precautions: Do not allow product or rinse water to enter drains, sewers, or watercourses

Transport Information

UN Number: UN 2689
UN Proper Shipping Name: 1,3-Dibromopropane
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Marine Pollutant: Yes
Special Transport Precautions: Protect from physical damage, secure during transport, avoid exposure to heat and incompatible goods

Regulatory Information

OSHA Classification: Hazardous chemical according to OSHA Hazard Communication Standard
TSCA Inventory: Listed
REACH Status: Not fully registered, pre-registered status only
SARA Title III: Not a listed Extremely Hazardous Substance, not subject to Section 313
Other Regulatory Listings: Subject to regulation by various international agencies, refer to local requirements