MSDS: 1,2-Dibromobenzene

Identification

Chemical Name: 1,2-Dibromobenzene
Synonyms: o-Dibromobenzene, ortho-Dibromobenzene
Chemical Formula: C6H4Br2
CAS Number: 583-53-9
Recommended Use: Organic synthesis, chemical intermediate, laboratory reagent
Supplier: Chemical supply companies; contact details provided on label
Emergency Phone: Refer to local country-specific poison control or supplier

Hazard Identification

Classification: Acute toxicity (oral, dermal, inhalation), Eye irritation, Skin irritation
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, toxic to aquatic life with long-lasting effects
Pictograms: Exclamation mark, environment
Precautionary Statements: Avoid skin contact, wash thoroughly after handling, avoid release to the environment
Potential Health Effects: Short-term overexposure leads to dizziness, headache, respiratory tract irritation, redness or dryness of skin

Composition / Information on Ingredients

Chemical Identity: 1,2-Dibromobenzene
Common Name: ortho-Dibromobenzene
Content: >99% by weight
Impurities: Trace isomers possible; check CoA for specification
Concentration Ranges: Main ingredient only

First Aid Measures

Inhalation: Move person to fresh air, monitor breathing, seek medical attention for persistent symptoms
Skin Contact: Remove contaminated clothing, wash with water and soap for fifteen minutes, seek care if irritation develops
Eye Contact: Rinse cautiously with water for several minutes, do not rub eyes, remove contact lenses if present, continue rinsing, seek medical advice
Ingestion: Rinse mouth, never give anything by mouth to an unconscious person, do not induce vomiting, consult poison center or healthcare provider right away
Most Important Symptoms/Effects: Irritation, coughing, headache, nausea, possible allergic reaction

Fire-Fighting Measures

Suitable Extinguishing Media: Foam, dry chemical, carbon dioxide, water spray in small quantities
Specific Hazards: Emits toxic fumes of hydrogen bromide, phenolic compounds, and carbon oxides when heated
Advice for Firefighters: Wear self-contained breathing apparatus and protective clothing, avoid inhaling vapors, control runoff water
Firefighting Precautions: Move containers from fire area if safe, use water mist to cool exposed containers, prevent contamination of water sources

Accidental Release Measures

Personal Precautions: Ventilate area, keep unnecessary personnel away, avoid breathing vapors and contact with skin or eyes, wear gloves and chemical goggles
Environmental Precautions: Keep product out of sewers and waterways
Methods for Cleanup: Absorb with inert material (sand, vermiculite), place in closed containers for disposal, clean spill area thoroughly
Emergency Procedures: Notify authorities if large spill enters environment

Handling and Storage

Handling: Use only in well-ventilated areas, avoid inhaling vapors or aerosols, prevent spills, wash thoroughly after handling, keep containers tightly closed
Storage: Store in a cool, dry place away from direct sunlight, incompatible substances, and ignition sources, keep in original container, clearly labeled, prevent moisture entry
Specific End Uses: Laboratory and industrial applications, follow supplier directions

Exposure Controls and Personal Protection

Engineering Controls: Use fume hood, provide local exhaust ventilation, implement mechanical ventilation if needed
Personal Protective Equipment - Eye/Face: Wear safety goggles or face shield
Personal Protective Equipment - Skin: Chemical-resistant gloves (nitrile, PVC), lab coat, barrier creams discouraged
Personal Protective Equipment - Respiratory: Use particulate respirator or organic vapor mask if airborne levels exceed recommended limits
Hygiene Measures: Avoid eating, drinking, or smoking in work area, wash hands after handling, launder contaminated clothing before reuse
Environmental Exposure Controls: Prevent release into drains, use spill control procedures, monitor emissions regularly
Recommended Exposure Limits: No workplace exposure limit established, control as hazardous chemical

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Aromatic, somewhat sweet
Odor Threshold: Not established
pH: Not applicable
Melting Point: 21-22°C (70-72°F)
Boiling Point: 220-222°C (428-432°F)
Flash Point: 93°C (closed cup)
Evaporation Rate: Not documented
Flammability: Not highly flammable, can burn under intense heat
Vapor Pressure: 0.15 mmHg at 25°C
Vapor Density: 6.7 (air = 1)
Relative Density: 2.13 g/cm³ at 25°C
Solubility: Negligible in water, soluble in organic solvents like ethanol, ether
Partition Coefficient (log Kow): 3.9
Auto-ignition Temperature: Not tested
Decomposition Temperature: No data
Viscosity: No reliable data

Stability and Reactivity

Chemical Stability: Remains stable under normal storage conditions
Reactivity: Does not react violently under normal temperatures and pressures
Possibility of Hazardous Reactions: Contact with strong oxidizers leads to exothermic reactions
Conditions to Avoid: High temperature, sources of ignition, direct sunlight, contact with incompatible materials like strong bases or oxidizers
Incompatible Materials: Alkali metals, strong bases, strong oxidizing agents, powdered metals
Hazardous Decomposition Products: Hydrogen bromide, bromine fumes, carbon oxides, phenolic compounds

Toxicological Information

Routes of Exposure: Inhalation, ingestion, dermal, ocular
Acute Toxicity: Oral LD50 (rat): 2300 mg/kg; Dermal LD50: not established; Inhalation: no data
Irritation: Causes skin, eye, and respiratory tract irritation
Sensitization: Not reported
Chronic Effects: Long-term or repeated exposure may damage liver or kidneys, no evidence of carcinogenicity in available studies
Mutagenicity: Data unavailable
Carcinogenicity: Not classified by IARC or NTP
Reproductive Effects: Data insufficient for assessment
Target Organ Effects: Prolonged overexposure may impact nervous system, blood, liver

Ecological Information

Ecotoxicity: Very toxic to aquatic invertebrates and fish; long-lasting harmful effects possible
Persistence and Degradability: Slow biodegradation, persists under some conditions
Bioaccumulation: Potential for high bioaccumulation based on log Kow value
Mobility in Soil: Limited mobility, tends to adsorb on soil particles, not likely to leach deeply
Other Adverse Effects: No known ozone depletion, but contributes to long-term ecosystem damage if released unchecked

Disposal Considerations

Waste Treatment Methods: Incinerate under controlled conditions at licensed facility, avoid landfill disposal
Disposal of Contaminated Packaging: Rinse containers with suitable solvent, send for recycling or incinerate, follow local hazardous waste regulations
Precautions: Prevent release to environment, track waste from generation to disposal
Special Instructions: Label waste appropriately, keep in sealed containers until removal

Transport Information

UN Number: 1993 (when shipped as flammable liquid NOS)
UN Proper Shipping Name: Dibromobenzenes, liquid
Transport Hazard Class: 6.1 (toxic substances)
Packing Group: III
Marine Pollutant: Yes
Transport Labels: Toxic, environmentally hazardous
Special Precautions: Secure tightly closed, keep upright, store away from food and feed

Regulatory Information

U.S. Regulations: TSCA listed, SARA 313 reportable, RCRA hazardous waste
EU Regulations: REACH registered, CLP classified as hazardous
Other International Listings: Listed on Canadian DSL, Australian AICS, Japanese ENCS
Restrictions: Regulated for workplace exposure and environmental discharge
Labeling Requirements: Comply with GHS; hazard pictograms and precautionary phrases