MSDS: Β-Bromoethyl-Benzene

Identification

Product Name: Β-Bromoethyl-Benzene
Synonyms: 2-Phenylethyl bromide, Benzene, (2-bromoethyl)-
CAS Number: 103-63-9
Recommended Use: Used as an intermediate in organic synthesis, especially for pharmaceutical and fine chemical production
Supplier Information: Manufacturer and supplier details should be available on container label or receipt
Contact in Emergency: Local emergency response/fire department, company safety officer, poison control center

Hazard Identification

Classification: Harmful if inhaled or swallowed, causes skin and eye irritation, may cause respiratory irritation
Hazard Statements: H302 (harmful if swallowed), H315 (causes skin irritation), H319 (causes serious eye irritation), H335 (may cause respiratory irritation)
Signal Word: Warning
Pictograms: Exclamation mark (irritant), health hazard symbol
Precautionary Statements: Wash hands thoroughly after handling, wear protective gloves and safety goggles, use in well-ventilated area
Potential Health Effects: Headache, dizziness, nausea, local skin redness, coughing, possible drowsiness, potential for central nervous system depression

Composition / Information on Ingredients

Chemical Name: Β-Bromoethyl-Benzene
Chemical Formula: C8H9Br
Molecular Weight: 185.06 g/mol
Purity: ≥98%, impurities may cause additional hazards
Impurities: Trace benzene derivatives, unreacted starting materials—consider their hazards if present
Mixture/Single Substance: Single substance

First Aid Measures

Inhalation: Move affected person to fresh air promptly. Keep at rest. Maintain airway and breathing. Seek medical attention if respiratory symptoms develop.
Skin Contact: Remove any contaminated clothing, rinse skin with plenty of water (minimum 15 minutes). Get prompt medical attention for irritation or persistent symptoms.
Eye Contact: Rinse with clean water for 15 minutes, lifting eyelids occasionally. Remove contact lenses if present and easy to do.
Ingestion: Do not induce vomiting. Rinse mouth with water. Never give anything by mouth if person is unconscious. Seek medical advice right away.
Most Important Symptoms: Irritation to eyes, skin, respiratory tract; headache, nausea if inhaled
Note for Physician: Treat symptomatically, observe for delayed effects

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, foam, water spray (do not use direct water jets)
Specific Hazards: May release toxic fumes (hydrogen bromide, carbon oxides, phenyl radicals) under fire conditions
Protective Equipment for Firefighters: Self-contained breathing apparatus and full protective clothing needed
Firefighting Actions: Move containers from fire if safe. Cool closed drums exposed to flames with water spray. Prevent contaminated extinguishing water from entering drains.
Combustion Products: Hydrogen bromide, carbon monoxide, carbon dioxide, brominated hydrocarbons

Accidental Release Measures

Personal Precautions: Evacuate area, restrict access, avoid breathing fumes, prevent skin and eye contact
Protective Equipment: Chemical-resistant gloves, goggles, lab coat, appropriate respirator for vapors if needed
Emergency Procedures: Ventilate area, remove all sources of ignition, avoid generating vapor or dust
Environmental Precautions: Prevent leakage or seepage into soil, watercourses, drains. Notify regulatory agencies if contamination occurs.
Cleanup Methods: Absorb with inert materials (sand, diatomite), collect in tightly closed container for disposal. Clean area thoroughly after pickup.

Handling and Storage

Handling: Handle in chemical fume hood, minimize emission of vapors, avoid skin and eye contact. Keep containers closed and upright. Use tools and equipment that don’t generate sparks.
Hygienic Measures: Wash hands and face after work, do not eat, drink, or smoke in work areas. Remove contaminated clothing promptly.
Storage: Store in cool (2–8°C), dry, well-ventilated area, away from strong bases, acids, oxidizing agents, and sources of ignition. Keep container tightly sealed.
Incompatibilities: Avoid contact with strong oxidizers, alkali metals, strong bases and acids.

Exposure Controls and Personal Protection

Exposure Limits: No specific regulatory limits, but minimize exposure as much as possible by using engineering controls
Engineering Measures: Fume hood, local exhaust ventilation, use closed processes
Personal Protective Equipment: Chemical-resistant gloves (nitrile recommended), safety goggles with side-shields, flame-resistant lab coat, suitable respiratory protection if ventilation inadequate
General Safety Practices: Don’t touch face after handling, avoid inhaling or swallowing material, keep away from food and beverages
Environmental Controls: Use spill trays, proper waste disposal containers, routine workplace air monitoring

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Mild aromatic, sometimes pungent
Odor Threshold: Not available
pH: Not applicable
Melting Point/Freezing Point: -39°C
Boiling Point: 220–222°C
Flash Point: 108°C (closed cup)
Evaporation Rate: Not determined
Flammability: Combustible
Vapor Pressure: 0.02 mmHg at 25°C
Vapor Density: Greater than air
Relative Density: 1.368 g/cm³ at 20°C
Solubility: Insoluble in water, soluble in organic solvents (ether, benzene, chloroform)
Partition Coefficient (n-octanol/water): log Kow about 3.6
Auto-Ignition Temperature: 540°C
Decomposition Temperature: Not established
Viscosity: Not available

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions, sensitive to strong light, air, acids, and bases
Conditions to Avoid: Extreme heat, direct sunlight, sparks, open flame, incompatible substances
Incompatible Materials: Strong oxidizing agents, alkali metals, nitric acid, strong bases
Hazardous Decomposition Products: Hydrogen bromide, carbon monoxide, carbon dioxide, benzylic compounds
Hazardous Reactions: May undergo vigorous reaction with strong bases, may corrode some metals in moist environments

Toxicological Information

Acute Toxicity, Oral: LD50 (rat) around 1,000 mg/kg
Acute Toxicity, Dermal: Data limited; expected to cause irritation based on structure
Acute Toxicity, Inhalation: Effects can include coughing, respiratory tract irritation
Skin Corrosion/Irritation: Likely to cause with prolonged exposure
Serious Eye Damage/Irritation: Locally irritating; flushing eyes is critical
Respiratory Sensitization: Short exposure irritates throat and lungs
Carcinogenicity: No classification by IARC or NTP, based on available data
Mutagenicity: Data lacking, avoid contact
Reproductive Toxicity: Not adequately studied
Repeated Dose Toxicity: Possible damage to central nervous system with repeated high exposure

Ecological Information

Ecotoxicity: Harmful to aquatic life with long-lasting effects; avoid release to water systems
Persistence and Degradability: Not readily biodegradable, tends to persist in environment
Bioaccumulative Potential: Likely to bioaccumulate, based on log Kow
Mobility in Soil: Low mobility due to low solubility, but may leach depending on conditions
Other Adverse Effects: Avoid uncontrolled environmental release; inform relevant authorities if contamination occurs

Disposal Considerations

Disposal Methods: Treat as hazardous chemical waste; use approved incineration facility if available
Container Disposal: Triple rinse with compatible solvent, puncture and dispose following local regulations
Precautions: Do not pour into drains, waterways, or soil. Collect spilled material and waste in clearly labeled, leak-proof containers for licensed disposal
Regulatory Requirements: Comply with federal, state, and local environmental control regulations

Transport Information

UN Number: 1993
UN Proper Shipping Name: Flammable Liquid, N.O.S. (contains Β-Bromoethyl-Benzene)
Transport Hazard Class: 3 (flammable liquid)
Packing Group: III
Special Precautions: Avoid transport with oxidizers or foodstuffs, secure upright position, label containers appropriately
Hazard Label: Flammable liquid symbol required
Marine Pollutant: Yes

Regulatory Information

TSCA Status: Listed
EINECS Number: 203-134-7
OSHA Hazards: Harmful by inhalation, skin contact—regulated under chemical safety standards
SARA Title III: Section 311/312 (acute health hazard)
WHMIS Classification: D2B (Toxic material causing other toxic effects)
Reportable Quantity: Check local and federal guidance for reporting thresholds